Different Paths of Development of Two Information Systems Communities: A Comparative Study Based on Peer Interviews

Information Systems (IS) is not a homogeneous discipline. Rather, it is comprised of various communities that are characterized by different perspectives and methods. With regard to the ongoing discussion about the profile of the discipline, this is a remarkable phenomenon. More specifically, it recommends analyzing the characteristic features of the various IS communities and explaining the diverse paths of development they took. Furthermore, it implies the question whether—and how—the current diversity could be overcome in order to foster a more focused competition as well as a more coherent presentation of research results on an international scale. This article contributes to such an investigation. It is focused on a comparison of the international English-speaking community predominantly (in particular in its early days) shaped by North-American IS researchers, which plays a leading role in the international scene, and the IS discipline in German-speaking countries (”Wirtschaftsinformatik” or WI, in Austria, Germany, and Switzerland), which constitutes the largest IS community outside North America that maintains its own approach. The focus of this article is mainly on describing the communities’ characteristics as the outcome of a social construction that is chiefly influenced by those individuals who participated in this construction. Against this background, eight scholars from North America and six scholars from German-speaking countries were interviewed at length. All were chosen as witnesses of and important contributors to the development of their discipline. As a result of this reconstruction, the article presents a rich picture of the communities’ history and characteristics as experienced and reported by the interviewees. The results obtained from this project indicate that neither of the two conceptions (IS or WI) can serve as an ideal model. Instead, a more intensive international exchange among the various research communities, including the Scandinavian and British scholars, should contribute to further develop the field into a more mature and satisfactory state

Interactive decision support in hepatic surgery

BACKGROUND: Hepatic surgery is characterized by complicated operations with a significant peri- and postoperative risk for the patient. We developed a web-based, high-granular research database for comprehensive documentation of all relevant variables to evaluate new surgical techniques. METHODS: To integrate this research system into the clinical setting, we designed an interactive decision support component. The objective is to provide relevant information for the surgeon and the patient to assess preoperatively the risk of a specific surgical procedure. Based on five established predictors of patient outcomes, the risk assessment tool searches for similar cases in the database and aggregates the information to estimate the risk for an individual patient. RESULTS: The physician can verify the analysis and exclude manually non-matching cases according to his expertise. The analysis is visualized by means of a Kaplan-Meier plot. To evaluate the decision support component we analyzed data on 165 patients diagnosed with hepatocellular carcinoma (period 1996–2000). The similarity search provides a two-peak distribution indicating there are groups of similar patients and singular cases which are quite different to the average. The results of the risk estimation are consistent with the observed survival data, but must be interpreted with caution because of the limited number of matching reference cases. CONCLUSION: Critical issues for the decision support system are clinical integration, a transparent and reliable knowledge base and user feedback

Liver resection or combined chemoembolization and radiofrequency ablation improve survival in patients with hepatocellular carcinoma

Background/ Aims: To evaluate the long-term outcome of surgical and non-surgical local treatments of patients with hepatocellular carcinoma (HCC). Methods: We stratified a cohort of 278 HCC patients using six independent predictors of survival according to the Vienna survival model for HCC (VISUM- HCC). Results: Prior to therapy, 224 HCC patients presented with VISUM stage 1 (median survival 18 months) while 29 patients were classified as VISUM stage 2 (median survival 4 months) and 25 patients as VISUM stage 3 (median survival 3 months). A highly significant (p < 0.001) improved survival time was observed in VISUM stage 1 patients treated with liver resection ( n = 52; median survival 37 months) or chemoembolization (TACE) and subsequent radiofrequency ablation ( RFA) ( n = 44; median survival 45 months) as compared to patients receiving chemoembolization alone (n = 107; median survival 13 months) or patients treated by tamoxifen only (n = 21; median survival 6 months). Chemoembolization alone significantly (p <= 0.004) improved survival time in VISUM stage 1 - 2 patients but not (p = 0.341) in VISUM stage 3 patients in comparison to those treated by tamoxifen. Conclusion: Both liver resection or combined chemoembolization and RFA improve markedly the survival of patients with HCC

Global Entrepreneurship Monitor Unternehmensgründungen im weltweiten Vergleich: Länderbericht Deutschland 2021/22

Der Länderbericht Deutschland im Rahmen des Global Entrepreneurship Monitors gibt seit 1999 jährlich Auskunft über die Gründungsaktivitäten, -motive und -einstellungen in der deutschen Bevölkerung. Er wird vom deutschen Team des GEM unter Leitung von Prof. Rolf Sternberg herausgegeben.The country report of Germany of the Global Entrepreneurship Monitor (GEM) provides a yearly analysis of entrepreneurship activities, motives, and attitudes in the German population, since 1999. It is published by the German team of the GEM under the lead of Prof. Rolf Sternberg

A proposal to exploit galaxy-21cm synergies to shed light on the Epoch of Reionization

This white paper outlines the benefits of synergizing WFIRST, Subaru Hyper Suprime-Cam or other &gt;25m-class telescopes galaxy observations with SKA 21cm measurements to constrain the nature of reionization (ionization history and topology) and its sources. <p/

Global Entrepreneurship Monitor Unternehmensgründungen im weltweiten Vergleich: Länderbericht Deutschland 2020/21

Der Länderbericht Deutschland im Rahmen des Global Entrepreneurship Monitors gibt seit 1999 jährlich Auskunft über die Gründungsaktivitäten, -motive und -einstellungen in der deutschen Bevölkerung. Er wird vom deutschen Team des GEM unter Leitung von Prof. Rolf Sternberg herausgegeben.The country report of Germany of the Global Entrepreneurship Monitor (GEM) provides a yearly analysis of entrepreneurship activities, motives, and attitudes in the German population, since 1999. It is published by the German team of the GEM under the lead of Prof. Rolf Sternberg