La Bridoire – Pont-aqueduc dit « mur des Sarrasins »

La commune de La Bridoire est située dans l’avant-pays savoyard, au sud du lac d’Aiguebelette. Dans l’Antiquité, elle relevait de la cité de Vienne. À la sortie du bourg, de part et d’autre de la RD 203, se trouvent les vestiges du « mur des Sarrasins », identifiés comme ceux d’un pont-aqueduc. À l’est (fig. 1), subsistent deux murs de pierre, l’un ayant une forme de marche d’escalier, long de 15 m, au sommet duquel on distingue des départs d’arches, et l’autre, plus petit, long de 3 m pour u..

Impact of multiple disturbances on microbiological quality of urban and peri-urban lakes

10 p.International audienceThis project will focus on global changes impact on the microbiological quality of urban and peri-urban lakes in Ile-de-France (France). The goal is to better understand the impact of anthropogenic pressures and changes of land use on bacterial populations in urban lakes, to identify indicators of quality and ecological status and to better evaluate the ecology of emerging waterborne pathogens such as nontuberculous mycobacteria. The study will include an annual survey of forty eight lakes and a monthly monitoring of the Créteil Lake to assess the temporal and spatial variations of bacterial communities, faecal contamination indicators and nontuberculous mycobacteria. A supplementary study will be undertaken to identify the favorable habitats of mycobacteria in urban lakes

The Measurement of the Stratum Corneum Reservoir. A Predictive Method for In Vivo Percutaneous Absorption Studies: Influence of Application Time

The relation existing in vivo between the reservoir function of the stratum corneum following a 30-mm application time and the total percutaneous absorption of molecules applied for a longer time was studied on hairless rats. One thousand nanomoles of 4 radiolabeled molecules (theophylline, nicotinic acid, acetyl salicylic acid, benzoic acid) were applied on 1 cm2 of back skin for 0.5, 2, 4 and 6 h. The total recovery in excreta and the whole animal body were measured 4 days later in order to determine the level of absorption. A direct proportionality (r = 0.99) between the total percutaneous absorption of these compounds and the duration of their application was observed. This suggests that a constant flux of penetration does exist in vivo. The reservoir function of the stratum corneum was measured by successive stripping of the treated area. Following a 30-mm application, a strict correlation (r = 0.99) between the total amounts of molecules penetrated in 4 days and the amounts found in the reservoir of the horny layer was demonstrated.All together these findings show that the simple knowledge of the reservoir effect of the stratum corneum for a molecule applied for 30 mm allows the predictive assessment of its total penetration resulting from various times of application

Évolution des modèles d’élevage de porcs en Europe et impacts sur les performances technico-économiques

L’évolution de la production porcine depuis 2000 est caractérisée par une concentration structurelle très forte dans certains pays. Elle se traduit par une progression rapide des performances techniques du fait, au-delà du progrès génétique, de la disparition des élevages les moins efficaces, de la spécialisation des exploitations, de la modernisation des bâtiments et de l’amélioration consécutive de la situation sanitaire, des conditions de travail du personnel et de vie des animaux. Cette évolution se traduit aussi par une intensification de l’élevage de porcs qui rencontre une opposition croissante dans la société.The evolution of pig production since 2000 is characterized by a structural concentration which is very strong in some countries. In addition to the genetic progress, it results in a rapid increase in technical performance because of the disappearance of the least efficient farms, specialization of farms, modernization of buildings and the resulting improvement in health status, conditions of working for staff and of life for animals. This trend also leads to the intensification of pig farming which meets a growing opposition in society