THROES: a caTalogue of HeRschel Observations of Evolved Stars. I. PACS range spectroscopy

This is the first of a series of papers presenting the THROES (A caTalogue of HeRschel Observations of Evolved Stars) project, intended to provide a comprehensive overview of the spectroscopic results obtained in the far-infrared (55-670 microns) with the Her- schel space observatory on low-to-intermediate mass evolved stars in our Galaxy. Here we introduce the catalogue of interactively reprocessed PACS (Photoconductor Array Camera and Spectrometer) spectra covering the 55-200 microns range for 114 stars in this category for which PACS range spectroscopic data is available in the Herschel Science Archive (HSA). Our sample includes objects spanning a range of evolutionary stages, from the asymptotic giant branch to the planetary nebula phase, displaying a wide variety of chemical and physical properties. The THROES/PACS catalogue is accessible via a dedicated web-based inter- face (https://throes.cab.inta-csic.es/) and includes not only the science-ready Herschel spectroscopic data for each source, but also complementary photometric and spectroscopic data from other infrared observatories, namely IRAS (Infrared Astronomical Satellite), ISO (Infrared Space Observatory) or AKARI, at overlapping wavelengths. Our goal is to create a legacy-value Herschel dataset that can be used by the scientific community in the future to deepen our knowledge and understanding of these latest stages of the evolution of low-to-intermediate mass stars.Comment: 38 page

Rhinolithiasis as cause of oronasal fistula

Rhinolithiasis is a disease caused by deposition of organic and inorganic compounds in the nasal cavity, leading to unilateral nasal obstruction, fetid rhinorrhea, epistaxis, and it may cause complications. The authors present a case of rhinolithiasis with oronasal fistula and literature review.A Rinolitíase é uma doença na qual ocorre a deposição de compostos orgânicos e inorgânicos em torno de um núcleo na cavidade nasal, causando rinorréia, obstrução nasal unilateral, odor fétido, epistaxe, podendo haver complicações. Os autores apresentam um caso de rinolitíase com fístula oronasal e revisão de literatura.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Setor de RinologiaUNIFESP, EPM, Setor de RinologiaSciEL

Hybrid confinement of optical and mechanical modes in a bullseye optomechanical resonator

Optomechanical cavities have proven to be an exceptional tool to explore fundamental and technological aspects of the interaction between mechanical and optical waves. Such interactions strongly benefit from cavities with large optomechanical coupling, high mechanical and optical quality factors, and mechanical frequencies larger than the optical mode linewidth, the so called resolved sideband limit. Here we demonstrate a novel optomechanical cavity based on a disk with a radial mechanical bandgap. This design confines light and mechanical waves through distinct physical mechanisms which allows for independent control of the mechanical and optical properties. Our device design is not limited by unique material properties and could be easily adapted to allow large optomechanical coupling and high mechanical quality factors with other promising materials. Finally, our demonstration is based on devices fabricated on a commercial silicon photonics facility, demonstrating that our approach can be easily scalable.Comment: 16 pages, 11 figure

Lattice model of ionic liquid confined by metal electrodes

We study, using Monte Carlo simulations, the density profiles and differential capacitance of ionic liquids confined by metal electrodes. To compute the electrostatic energy, we use the recently developed approach based on periodic Green’s functions. The method also allows us to easily calculate the induced charge on the electrodes permitting an efficient implementation of simulations in a constant electrostatic potential ensemble. To speed up the simulations further, we model the ionic liquid as a lattice Coulomb gas and precalculate the interaction potential between the ions. We show that the lattice model captures the transition between camel-shaped and bell-shaped capacitance curves—the latter characteristic of ionic liquids (strong coupling limit) and the former of electrolytes (weak coupling). We observe the appearance of a second peak in the differential capacitance at ≈0.5 V for 2:1 ionic liquids, as the packing fraction is increased. Finally, we show that ionic size asymmetry decreases substantially the capacitance maximum, when all other parameters are kept fixed

Endoscopic endonasal ligation of the esphenopalatine artery for severe epistaxis

Introduction: Severe epistaxis, usually associated to hypertension and blood dyscrasia, may benefit from surgery when the conservative treatment fails. Aim: to evaluate the results of endoscopic endonasal ligation of the sphenopalatine artery for non-responsive severe epistaxis. Study design: Clinical prospective. Material and Method: chart review of twelve patients submitted to endoscopic endonasal ligation of the sphenopalatine artery regarding clinical aspects, predisposing factors and complications of the procedure. Results: the mean age was 50.9 years, and the male:female: ratio was 2:1. Hypertension was presented in 33% and hematologic disorders in 16.6% of the patients. One patient, 8.3%, presented a new bleeding episode after the surgery. Discussion: the endoscopic endonasal ligation of the sphenopalatine artery, proved to be a safe surgical method and presented 8.3% of bleeding after the procedure in our study. Conclusion: avoiding the complications of previous surgical treatments for severe epistaxis, the endoscopic endonasal ligation of the sphenopalatine artery is an effective technique affordable for otolaryngologists with practice in endoscopic endonasal surgery.Introdução: A epistaxe severa, geralmente associada a fatores predisponentes como hipertensão arterial sistêmica e coagulopatia, é uma doença desafiadora, e pode necessitar de uma abordagem cirúrgica nos casos que não respondem ao tratamento conservador, como cauterização e tamponamento nasal. Objetivo: avaliar os resultados da ligadura endoscópica endonasal da artéria esfenopalatina no tratamento da epistaxe severa refratária à abordagem terapêutica conservadora. Forma de estudo: Clínico prospectivo. Material e Método: foram avaliados doze casos de pacientes submetidos à ligadura endoscópica endonasal da artéria esfenopalatina no tratamento da epistaxe severa não responsiva ao tratamento conservador, observando-se a história clínica, os fatores predisponentes, a evolução e as complicações deste procedimento. Resultados: a idade média foi de 50,9 anos, e a distribuição por sexo foi de 33% do sexo feminino e 67% do sexo masculino; 33% apresentaram HAS e 16,6% coagulopatia (hepatopatia) como fatores predisponentes. Um paciente (8,3%) apresentou ressangramento após o procedimento cirúrgico. Discussão: a ligadura endoscópica endonasal da artéria esfenopalatina representa uma abordagem segura e garante um controle satisfatório do sangramento, com índice de ressangramento de 8,3% entre os nossos casos. Conclusão: a ligadura endoscópica endonasal da artéria esfenopalatina representa uma opção cirúrgica adequada, pois não apresenta as complicações das técnicas anteriores, atinge um controle satisfatório do sangramento e pode ser realizada por otorrinolaringologistas habituados à cirurgia endoscópica nasal.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Setor de RinologiaUNIFESP, EPM, Setor de RinologiaSciEL

A transcriptomic approach to the metabolism of tetrapyrrolic photosensitizers in a marine annelid

Funding Information: Funding: The authors also acknowledge DPGM (the Portuguese General Directorate for Marine Policy) for funding the MARVEN project (ref. FA_05_2017_007). The Portuguese Foundation for Science and Technology (FCT) funded project WormALL (PTDC/BTA-BTA/28650/2017), which includes the contract attributed to M.D. and the fellowship attributed to A.P.R. UCIBIO and LAQV are financed by national funds from FCT, UID/Multi/04378/2020 and UID/QUI/50006/2020, respectively. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.The past decade has seen growing interest in marine natural pigments for biotechnological applications. One of the most abundant classes of biological pigments is the tetrapyrroles, which are prized targets due their photodynamic properties; porphyrins are the best known examples of this group. Many animal porphyrinoids and other tetrapyrroles are produced through heme metabolic pathways, the best known of which are the bile pigments biliverdin and bilirubin. Eulalia is a marine Polychaeta characterized by its bright green coloration resulting from a remarkably wide range of greenish and yellowish tetrapyrroles, some of which have promising photodynamic properties. The present study combined metabolomics based on HPLC-DAD with RNA-seq transcriptomics to investigate the molecular pathways of porphyrinoid metabolism by comparing the worm’s proboscis and epidermis, which display distinct pigmentation patterns. The results showed that pigments are endogenous and seemingly heme-derived. The worm possesses homologs in both organs for genes encoding enzymes involved in heme metabolism such as ALAD, FECH, UROS, and PPOX. However, the findings also indicate that variants of the canonical enzymes of the heme biosynthesis pathway can be species-and organ-specific. These differences between molecular networks contribute to explain not only the differential pigmentation patterns between organs, but also the worm’s variety of novel endogenous tetrapyrrolic compounds.publishersversionpublishe

Accidental and late parasitological diagnosis of Leishmania sp. in a dog from a low disease transmission area of Brazil: a case report

Canine Leishmaniasis diagnosis must be fast and accurate since dogs are urban reservoirs of the disease and earlier therapeutic intervention is more clinically effective. However, this still represents a challenge, particularly in low transmission areas. The present report describes the difficulties of clinical suspicion and the late diagnosis of a dog infected with Leishmania sp

Topsy-Turvy Neo-Developmentalism: An Analysis of the Current Brazilian Model of Development*

A B S T R AC T | The paper discusses the similarities and differences between neo-developmentalism and neo-extractivism. The evaluation compares Brazil with nine other Latin American countries and is based on a framework that considers both economic policies and their outcomes. On the policy side, it looks at income, monetary, international trade, industrial and mineral resource policies; on the outcome side, it observes the composition of both exports and the Gross Domestic Product. In the end, we argue that neo-developmentalism and neo-extractivism are actually variations of the same development route and may face similar challenges in the long term. Neodesarrolismo al revés: un análisis del actual modelo brasileño de desarrollo R E S U M E N | El artículo analiza las similitudes y diferencias entre el neodesarrollismo y el neoextractivismo. Esta revisión compara Brasil con otros nueve países de América Latina y utiliza como base un modelo que considera las políticas económicas y sus resultados. Por el lado de la política, considera la política económica, industrial, de comercio internacional, ingresos y recursos minerales. Por el lado de los resultados, observa la composición de las exportaciones y el PIB. Por último, se argumenta que el neodesarrollismo y neoextractivismo en realidad son variaciones de la misma vía de desarrollo y tienden a enfrentar los mismos desafíos en el largo plazo. PA L A B R A S C L AV E | Neodesarrollismo, neoextractivismo, desarrollo, América Latina. Neodesenvolvimento ao contrário: uma análise do atual modelo brasileiro de desenvolvimento R E S U M O | Este artigo analisa as semelhanças e as diferenças entre o neodesenvolvimentismo e o neoextrativismo. Esta revisão compara o Brasil com outros nove países da América Latina e utiliza como base um modelo que considera as políticas econômicas e seus resultados. No que se refere à política, considera as políticas de renda, monetária, de comércio internacional, industrial e de recursos minerais. Quanto aos resultados, observa a composição das exportações e o PIB. Por último, argumenta-se que o neodesenvolvimentismo e o neoextrativismo em realidade são variações da mesma via de desenvolvimento e tendem a enfrentar os mesmos desafios em longo prazo

Topsy-Turvy Neo-Developmentalism: An Analysis of the Current Brazilian Model of Development*

A B S T R AC T | The paper discusses the similarities and differences between neo-developmentalism and neo-extractivism. The evaluation compares Brazil with nine other Latin American countries and is based on a framework that considers both economic policies and their outcomes. On the policy side, it looks at income, monetary, international trade, industrial and mineral resource policies; on the outcome side, it observes the composition of both exports and the Gross Domestic Product. In the end, we argue that neo-developmentalism and neo-extractivism are actually variations of the same development route and may face similar challenges in the long term. Neodesarrolismo al revés: un análisis del actual modelo brasileño de desarrollo R E S U M E N | El artículo analiza las similitudes y diferencias entre el neodesarrollismo y el neoextractivismo. Esta revisión compara Brasil con otros nueve países de América Latina y utiliza como base un modelo que considera las políticas económicas y sus resultados. Por el lado de la política, considera la política económica, industrial, de comercio internacional, ingresos y recursos minerales. Por el lado de los resultados, observa la composición de las exportaciones y el PIB. Por último, se argumenta que el neodesarrollismo y neoextractivismo en realidad son variaciones de la misma vía de desarrollo y tienden a enfrentar los mismos desafíos en el largo plazo. PA L A B R A S C L AV E | Neodesarrollismo, neoextractivismo, desarrollo, América Latina. Neodesenvolvimento ao contrário: uma análise do atual modelo brasileiro de desenvolvimento R E S U M O | Este artigo analisa as semelhanças e as diferenças entre o neodesenvolvimentismo e o neoextrativismo. Esta revisão compara o Brasil com outros nove países da América Latina e utiliza como base um modelo que considera as políticas econômicas e seus resultados. No que se refere à política, considera as políticas de renda, monetária, de comércio internacional, industrial e de recursos minerais. Quanto aos resultados, observa a composição das exportações e o PIB. Por último, argumenta-se que o neodesenvolvimentismo e o neoextrativismo em realidade são variações da mesma via de desenvolvimento e tendem a enfrentar os mesmos desafios em longo prazo