Profile of aerobic fitness and muscle power of athletes on the Brazilian National Paralympic Five-a-side Football Team

We aimed to profile the aerobic fitness and muscle power of five-a-side football athletes on the Brazilian National Paralympic Team. The sample consisted of 12 male Paralympic athletes on the Brazilian National five-a-side football team, including 3 sighted goalkeepers and 9 blind (B1 category) outfield players. The results were: peak oxygen uptake (VO2 peak), 51.8 ± 5.8 ml/kg/min; maximum speed, 17.1 ± 1.4 km/h and VO2 ventilatory threshold (VT), 40.2 ± 6.5 ml/kg/min The peak torque values (Nm) of the right and left legs were 241 ± 48 and 234 ± 45 for 60° extension, 127 ± 17 and 123 ± 16 for 60° flexion, 170 ± 29 and 162 ± 28 for 180° extension, 113 ± 13 and 109 ± 13 for 180° flexion, 130 ± 20 and 129 ± 23 for 300° extension, and 118 ± 17 and 115 ± 18 for 300° flexion, respectively. The five-a-side football players on the Brazilian National Paralympics Team exhibited physiologically normal responses to physical training related to the observed physical capacities as shown by the aerobic fitness and muscle power results observed. These results suggest that blind individuals can improve their physical capacity regardless of their visual impairment

In vivo comparative study of the effects of using the enamel matrix derivative and/or photobiomodulation on the repair of bone defects

The repair of bone defects has been the subject of many studies that have shown inconclusive results as to what is the best bone substitute. Bone defects (Ø 2 mm) were induced on the tibia of seventy-two rats, which were distributed into the following

Experimental Gastric Carcinogenesis in Cebus apella Nonhuman Primates

The evolution of gastric carcinogenesis remains largely unknown. We established two gastric carcinogenesis models in New-World nonhuman primates. In the first model, ACP03 gastric cancer cell line was inoculated in 18 animals. In the second model, we treated 6 animals with N-methyl-nitrosourea (MNU). Animals with gastric cancer were also treated with Canova immunomodulator. Clinical, hematologic, and biochemical, including C-reactive protein, folic acid, and homocysteine, analyses were performed in this study. MYC expression and copy number was also evaluated. We observed that all animals inoculated with ACP03 developed gastric cancer on the 9th day though on the 14th day presented total tumor remission. In the second model, all animals developed pre-neoplastic lesions and five died of drug intoxication before the development of cancer. The last surviving MNU-treated animal developed intestinal-type gastric adenocarcinoma observed by endoscopy on the 940th day. The level of C-reactive protein level and homocysteine concentration increased while the level of folic acid decreased with the presence of tumors in ACP03-inoculated animals and MNU treatment. ACP03 inoculation also led to anemia and leukocytosis. The hematologic and biochemical results corroborate those observed in patients with gastric cancer, supporting that our in vivo models are potentially useful to study this neoplasia. In cell line inoculated animals, we detected MYC immunoreactivity, mRNA overexpression, and amplification, as previously observed in vitro. In MNU-treated animals, mRNA expression and MYC copy number increased during the sequential steps of intestinal-type gastric carcinogenesis and immunoreactivity was only observed in intestinal metaplasia and gastric cancer. Thus, MYC deregulation supports the gastric carcinogenesis process. Canova immunomodulator restored several hematologic measurements and therefore, can be applied during/after chemotherapy to increase the tolerability and duration of anticancer treatments

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others