Evolution of time preference by natural selection

We reexamine Rogers’ (1994) analysis of the biological basis of the rate of time preference. Although his basic insight concerning the derivation of the felicity function holds up, the functional form he uses does not generate the evolutionary equilibrium behavior. Moreover, Rogers relies upon an interior solution for a particular kind of intergenerational transfer. We show such interior solutions do not generally arise. Hence Rogers most striking prediction, namely that the real interest rate should be about 2% per annum, does not follow

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy

Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings. This case report highlights the risk of Torsade de Pointes, a life-threatening cardiac arrhythmia, in a heroin-dependent patient receiving methadone substitution therapy who was prescribed itraconazole for vaginal thrush. The patient presented to the accident and emergency department for chest discomfort and an episode of syncope following two doses of itraconazole (200 mg). Electrocardiogram monitoring at the accident and emergency department showed prolonged rate-corrected QT interval leading to Torsade de Pointes. The patient was admitted for cardiac monitoring, and electrocardiogram returned to normal upon discontinuation of methadone. Implication. This cardiac arrhythmia was most likely as a result of a drug interaction between methadone and itraconazole because the patient presented with no other risk factors. Conclusion. Given the benefits of methadone as a substitution treatment for heroin-dependent individuals, the association between methadone and cardiac arrhythmias is of great concern. Physicians treating heroin-dependent patients on methadone substitution therapy should therefore be cautious of the potential risk of drug interactions that may lead to fatal cardiac arrhythmias

Is friction responsible for the reduction of fusion rates far below the Coulomb barrier?

The fusion of two interacting heavy ions traditionally has been interpreted in terms of the penetration of the projectile into the target. Observed rates well below the Coulomb barrier are considerably lower than estimates obtained from penetration factors. One approach in the analysis of the data invokes coupling to non-elastic channels in the scattering as the source of the depletion. Another is to analyze those data in terms of tunneling in semi-classical models, with the observed depletion being taken as evidence of a ``friction'' under the barrier. A complementary approach is to consider such tunneling in terms of a fully quantal model. We investigate tunneling with both one-dimensional and three-dimensional models in a fully quantal approach to investigate possible sources for such a friction. We find that the observed phenomenon may not be explained by friction. However, we find that under certain conditions tunneling may be enhanced or diminished by up to 50%, which finds analogy with observation, without the invocation of a friction under the barrier.Comment: 18 pages, 15 figures embedde

Last scattering, relic gravitons and the circular polarization of the CMB

The tensor contribution to the $V$-mode polarization induced by a magnetized plasma at last scattering vanishes exactly. Conversely a polarized background of relic gravitons cannot generate a $V$-mode polarization. The reported results suggest that, in the magnetized $\Lambda$CDM paradigm, the dominant source of circular dichroism stems from the large-scale fluctuations of the spatial curvature.Comment: 8 pages, no figure

Incoherent single pion electroproduction on the deuteron with polarization effects

Incoherent pion electroproduction on the deuteron is studied from threshold up to the second resonance region with special emphasis on the influence of final state interaction, in particular on polarization observables. The elementary $\gamma N\to\pi N$ amplitude is taken from the MAID-2003 model. Final state interaction is included by considering complete rescattering in the final $NN$ and $\pi N$ subsystems. Their influence on the structure functions governing the semi-exclusive differential cross section, where besides the scattered electron only the produced pion is detected, is investigated in detail. For charged pion-production the effect of $NN$-rescattering is moderate whereas $\pi N$-rescattering is almost negligible, except very close to threshold. $NN$-rescattering appears much stronger in neutral pion production for which the primary mechanism is the elimination of a significant spurious coherent contribution in the impulse approximation. Sizeable effects are also found in some of the polarization structure functions for beam and/or target polarizations.Comment: 20 pages including 14 figure

Six Pillars of Social Policy: The State of Pensions and Health Care in Canada

William B.P. Robson, a co-author with David Slater of a series of papers on pension issues, has written an ambitious survey of the state of Canadian economic policy in the areas of pensions and health care. He argues that it is appropriate to tackle both issues in the same paper because they are both major spending programs strongly related to the life cycle of Canadians, and face challenges arising from the aging of the population. Robson notes that the pension debate uses the metaphor of three pillars to describe a comprehensive pension system: a safety net to guard against destitution in old age; a mandatory employment-related system to provide basic replacement income; and a voluntary system supported by provisions that reduce the double-taxation of saving. The main elements of public policy related to pensions in Canada cover these pillars. He recognizes that all three of the pillars cannot be directly applied to health care, but he argues that the three-pillar metaphor is still a fruitful perspective because it facilitates constructive responses to the pressures confronting Canada’s health system and illuminates interactions between the pension and health systems. Hence his title “six pillars of social policy”. Based on his examination of Canada’s pension and health-care systems, Robson makes a number of recommendations. First, he advocates more prefunding in both the pension and health areas to cover the future cost of the aging baby-boom cohort. Second, he recommends a gradual increase in the normal age of eligibility for pension benefits. Third, he recommends the creation of a second pillar, a mandatory contribution scheme in the health area as a way to avoid the development of a means-tested system that would exacerbate the disincentives to work and save. Fourth, he puts forward the idea of a new type of saving vehicle that provides tax-relief on distributions rather than on contributions so that Canadians can avoid the high marginal effective tax rates associated with means-tested programs.Health, Health Care, Health-care, Healthcare, Canada, Pensions, CPP, Retirement, Mandatory Contribution, Aging, Ageing

Parity of charged pions

This paper discusses the parity of charged pions. It is shown that the original determination of the parity of the negatively charged pion using the capture of negatively charged pions in deuterium to form two neutrons is not conclusive if the pion has

Incoherent pion photoproduction on the deuteron with polarization observables I: Formal expressions

Formal expressions are developed for the general five-fold differential cross section of incoherent $\pi$-photoproduction on the deuteron including beam and target polarization. The polarization observables of the cross section are described by various beam, target and beam-target asymmetries for polarized photons and/or polarized deuterons. They are given as bilinear hermitean forms in the reaction matrix elements divided by the unpolarized cross section. In addition, the corresponding observables for the semi-exclusive reaction $\vec d(\vec \gamma,\pi)NN$ are also given.Comment: 11 pages, 1 figur

Reply to ``Comment on ``Lateral Casimir Force beyond the Proximity Force Approximation'' ''

We reply to the comment arXiv:quant-ph/0702060 on our letter arXiv:quant-ph/0603120 [Phys. Rev. Lett. 96, 100402 (2006)]Comment: 1 pag