Hosting Policy Fellows: a guide for Higher Education Institutions

Policy Fellowships, where academics and policy professionals spend time in each other’s organisations to exchange knowledge, are becoming a far more visible and common method of supporting academic-policy engagement. From 2020-22 CAPE adapted the model pioneered by the Cambridge Centre for Science and Policy (CSaP) to run a pilot collaborative Policy Fellowship programme, whereby policy professionals spent time in CAPE universities meeting academics and research services staff. Based upon our experience, our new guide Hosting Policy Fellows: a guide for Higher Education Institutions shares knowledge, processes, and procedures of setting up and delivering a Policy Fellowship programme alongside indications of resourcing and timelines. It also provides templates that universities can use. Our aim is to support HEIs who wish to run, formalise, or get involved in existing Policy Fellowship programmes as part of their wider academic-policy engagement strategies

Analytics for characterising and measuring the naturalness of online personae

Currently 40 % of the world’s population, around 3 billion users, are online using cyberspace for everything from work to pleasure. While there are numerous benefits accompanying this medium, the Internet is not without its perils. In this case study article, we focus specifically on the challenge of fake (or unnatural) online identities, such as those used to defraud people and organisations, with the aim of exploring an approach to detect them

The assessment of left ventricular diastolic function: guidance and recommendations from the British Society of Echocardiography

Impairment of left ventricular (LV) diastolic function is common amongst those with left heart disease and is associated with significant morbidity. Given that, in simple terms, the ventricle can only eject the volume with which it fills and that approximately one half of hospitalisations for heart failure (HF) are in those with normal/’preserved’ left ventricular ejection fraction (HFpEF) (Bianco et al. in JACC Cardiovasc Imaging. 13:258–271, 2020. 10.1016/j.jcmg.2018.12.035), where abnormalities of ventricular filling are the cause of symptoms, it is clear that the assessment of left ventricular diastolic function (LVDF) is crucial for understanding global cardiac function and for identifying the wider effects of disease processes. Invasive methods of measuring LV relaxation and filling pressures are considered the gold-standard for investigating diastolic function. However, the high temporal resolution of trans-thoracic echocardiography (TTE) with widely validated and reproducible measures available at the patient’s bedside and without the need for invasive procedures involving ionising radiation have established echocardiography as the primary imaging modality. The comprehensive assessment of LVDF is therefore a fundamental element of the standard TTE (Robinson et al. in Echo Res Pract7:G59–G93, 2020. 10.1530/ERP-20-0026). However, the echocardiographic assessment of diastolic function is complex. In the broadest and most basic terms, ventricular diastole comprises an early filling phase when blood is drawn, by suction, into the ventricle as it rapidly recoils and lengthens following the preceding systolic contraction and shortening. This is followed in late diastole by distension of the compliant LV when atrial contraction actively contributes to ventricular filling. When LVDF is normal, ventricular filling is achieved at low pressure both at rest and during exertion. However, this basic description merely summarises the complex physiology that enables the diastolic process and defines it according to the mechanical method by which the ventricles fill, overlooking the myocardial function, properties of chamber compliance and pressure differentials that determine the capacity for LV filling. Unlike ventricular systolic function where single parameters are utilised to define myocardial performance (LV ejection fraction (LVEF) and Global Longitudinal Strain (GLS)), the assessment of diastolic function relies on the interpretation of multiple myocardial and blood-flow velocity parameters, along with left atrial (LA) size and function, in order to diagnose the presence and degree of impairment. The echocardiographic assessment of diastolic function is therefore multifaceted and complex, requiring an algorithmic approach that incorporates parameters of myocardial relaxation/recoil, chamber compliance and function under variable loading conditions and the intra-cavity pressures under which these processes occur. This guideline outlines a structured approach to the assessment of diastolic function and includes recommendations for the assessment of LV relaxation and filling pressures. Non-routine echocardiographic measures are described alongside guidance for application in specific circumstances. Provocative methods for revealing increased filling pressure on exertion are described and novel and emerging modalities considered. For rapid access to the core recommendations of the diastolic guideline, a quick-reference guide (additional file 1) accompanies the main guideline document. This describes in very brief detail the diastolic investigation in each patient group and includes all algorithms and core reference tables

Alien Registration- Robinson, Sadie (Bangor, Penobscot County)

https://digitalmaine.com/alien_docs/11112/thumbnail.jp

Alien Registration- Robinson, Sadie (Bangor, Penobscot County)

https://digitalmaine.com/alien_docs/11112/thumbnail.jp

Dick, the horse that kept the Sabbath.

Mode of access: Internet