7,081 research outputs found

    Should Sixth Grade be in Elementary or Middle School? An Analysis of Grade Configuration and Student Behavior

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    Using administrative data on public school students in North Carolina, we find that sixth grade students attending middle schools are much more likely to be cited for discipline problems than those attending elementary school. That difference remains after adjusting for the socioeconomic and demographic characteristics of the students and their schools. Furthermore, the higher infraction rates recorded by sixth graders who are placed in middle school persist at least through ninth grade. A plausible explanation is that sixth graders are at an especially impressionable age; in middle school, the exposure to older peers and the relative freedom from supervision have deleterious consequences.

    The density of critical percolation clusters touching the boundaries of strips and squares

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    We consider the density of two-dimensional critical percolation clusters, constrained to touch one or both boundaries, in infinite strips, half-infinite strips, and squares, as well as several related quantities for the infinite strip. Our theoretical results follow from conformal field theory, and are compared with high-precision numerical simulation. For example, we show that the density of clusters touching both boundaries of an infinite strip of unit width (i.e. crossing clusters) is proportional to (sinπy)5/48{[cos(πy/2)]1/3+[sin(πy/2)]1/31}(\sin \pi y)^{-5/48}\{[\cos(\pi y/2)]^{1/3} +[\sin (\pi y/2)]^{1/3}-1\}. We also determine numerically contours for the density of clusters crossing squares and long rectangles with open boundaries on the sides, and compare with theory for the density along an edge.Comment: 11 pages, 6 figures. Minor revision

    Neuronal Cell Model and Methods of Use Thereof

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    We previously described a novel in vitro model of a non-productive herpes simplex virus type 1 (HSV-1) infection in neurally-differentiated (ND)-PC12 cells that allows for inducible virus replication upon forskolin and heat stress (HS) treatment. In this research, we further characterized the model with respect to HSV-2 strain 333. We found that: (i) ND-PC12 cells are non-permissive to HSV-2 replication; (ii) HSV-2 can establish a quiescent infection, like HSV-1, in ND-PC12 cells with the transient use of acycloguanosine (ACV); however unlike HSV-1, anti-viral conditions are not obligatory to establish and maintain a quiescent state; (iii) the quiescent state is maintained in the presence of Vero cell cocultivation indicating that such cultures are free of infectious virus; and (iv) a high percentage of quiescently infected (QIF)-PC 12 cell cultures (80-100%) produce HSV-2 in response to forskolin and HS (43° C., 3 h) treatment for as long as 4 weeks post infection. These findings indicate that ND-PC12 cells can harbor HSV-2 in a cryptic and non-productive state that is reversible. This model has appealing features for studying gene expression during the establishment, maintenance and reactivation phases of the HSV-2 quiescent state in cell culture. Journal of Neuro Virology (2000) 6, 296-302

    Neuronal Cell Model and Methods of Use Therefor

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    The present invention provides, inter alia, a PC12 cell quiescently infected with a neurotropic virus. Preferred quiescently-infected neural cells are those wherein the neurotropic virus is a neurotropic herpes virus. Methods related to these and other materials are also provided

    Anchored Critical Percolation Clusters and 2-D Electrostatics

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    We consider the densities of clusters, at the percolation point of a two-dimensional system, which are anchored in various ways to an edge. These quantities are calculated by use of conformal field theory and computer simulations. We find that they are given by simple functions of the potentials of 2-D electrostatic dipoles, and that a kind of superposition {\it cum} factorization applies. Our results broaden this connection, already known from previous studies, and we present evidence that it is more generally valid. An exact result similar to the Kirkwood superposition approximation emerges.Comment: 4 pages, 1 (color) figure. More numerics, minor corrections, references adde
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