2,315 research outputs found
Book Reviews
Reviews of the following books: A Manual for Field Workers by Edward D. Ives; The Blaine House: Home of Maine\u27s Governors by H. Draper Hunt; Maine Bibliographies: A Bibliographical Guide by Elizabeth Ring; Maine During the Colonial Period: A Bibliographical Guide by Charles E. Clar
Identification of body fat tissues in MRI data
In recent years non-invasive medical diagnostic techniques have been used widely in medical investigations. Among the various imaging modalities available, Magnetic Resonance Imaging is very attractive as it produces multi-slice images where the contrast between various types of body tissues such as muscle, ligaments and fat is well defined. The aim of this paper is to describe the implementation of an unsupervised image analysis algorithm able to identify the body fat tissues from a sequence of MR images encoded in DICOM format. The developed algorithm consists of three main steps. The first step pre-processes the MR images in order to reduce the level of noise. The second step extracts the image areas representing fat tissues by using an unsupervised clustering algorithm. Finally, image refinements are applied to reclassify the pixels adjacent to the initial fat estimate and to eliminate outliers. The experimental data indicates that the proposed implementation returns accurate results and furthermore is robust to noise and to greyscale in-homogeneity
Underwater acoustics research at the Woods Hole Oceanographic Institution, 1930-1960
Author Posting. © Acoustical Society of America, 2016. This article is posted here by permission of Acoustical Society of America for personal use, not for redistribution. The definitive version was published in Proceedings of Meetings on Acoustics 23 (2016): 070013, doi:10.1121/2.0000214.The Woods Hole Oceanographic Institution (WHOI) was founded in 1930, and throughout its
history has had a strong involvement in research into the science and applications of sound in the
ocean. In terms of a brief history, three eras stand out: (1) pre-WWII, (2) WWII, and (3) the
postwar years. This manuscript will focus on the history of the most influential and colorful, individuals
and stories that arose during the war years. Provided are personal reminiscences, technical report details,
and photos illustrating the achievements, and importance, in underwater sound research at WHOI during
that time.This work was supported by
ONR Grant N00014-14-1-0040/N00014-16-1-2361
Results of 1/4-Scale Experiments. Vapor Simulant And Liquid Jet A Tests
A quarter-scale engineering model of the center wing tank (CWT) of a 747-100 was constructed. This engineering model replicated the compartmentalization, passageways, and venting to the atmosphere. The model was designed to scale the fluid dynamical and combustion aspects of the explosion, not the structural failure of the beams or spars. The effect of structural failure on combustion was examined by using model beams and spars with deliberately engineered weak connections to the main tank structure. The model was filled with a simulant fuel (a mixture of propane and hydrogen) and ignited with a hot wire. The simulant fuel was chosen on the basis of laboratory testing to model the combustion characteristics (pressure rise and flame speed) of Jet A vapor created by a Jet A liquid layer at 50C at an altitude of 13.8 kft.
A series of experiments was carried out in this model in order to: (a) investigate combustion in a CWT geometry; and (b) provide guidance to the TWA 800 crash investigation. The results of the experiments were observed with high-speed film, video, and still cameras, fast and slow pressure sensors, thermocouples, photodetectors, and motion sensors. A special pseudo-schlieren system was used to visualize flame propagation within the tank. This report describes the test program, facility, instrumentation, the first 30 experiments, comparisons between experiments, and performance of the instrumentation; then examines the significance of these results to the TWA 800 crash investigation.
The key results of this study are:
Flame Motion: The motion of flame was dominated by the effects of turbulence created by jetting through the passageways and vent stringers. A very rapid combustion event (lasting 10 to 20 ms) occurred once the flame traveled outside of the ignition bay and interacted with the turbulent flow. Most of the gas within the tank was burned during this rapid event.
Compartments: The combustion time decreased with an increasing number of compartments (bays) within the tank. With six bays, combustion took only 100 to 150 ms to be completed from the time of ignition until the end of the rapid combustion phase. The total combustion event was three to four times shorter with compartments than without.
Venting: Venting to the outside of the tank through the model vent stringers had a negligible effect on the combustion progress or on the peak pressure reached at the end of the burn.
Ignition Location: Variation of the ignition location produced distinctive pressure loads on the structural components.
Liquid Fuel: Lofting of a cold liquid fuel layer was produced by the combustion-induced gas motion. Although this spray of liquid eventually ignited and burned, it did not contribute to the pressure loading.
Structural Failure: Structural failure resulted in flame acceleration, decreasing the overall combustion time.
TWA 800 Investigation: The pressure loads were sufficiently high, up to 4 bar, and the combustion events were sufficiently short, that the forward portion (spanwise beam 3, front spar) of the CWT structure would fail as a direct consequence of the explosion. A combination of pressure loads was produced in some tests consistent with the TWA 800 wreckage. Replica tests, structural modeling, and sensitivity studies on fuel concentration are needed before any conclusions can be drawn about probable ignition locations.
Cargo Bay: Tests with a simplified model of a half-full cargo bay indicated that repeated pressure waves with an amplitude of 1 bar or less are produced when an explosion scenario similar to TWA 800 is tested.
Future Testing: Future studies should include replica tests, tests with Jet A vapor and warm liquid Jet A layers, and sensitivity tests to examine ignition location, fuel concentration, and vent area perturbations.
Summary: Explosion tests in a 747-100 CWT model reveal that a very complex pattern of combustion occurs due the interaction of the flame and the flow-generated turbulence. A wide range of structural load patterns occur, depending on the location of the ignition source. Some of these load patterns are consistent with damage believed to be associated with the initial explosion event in TWA 800. Sensitivity of the loading to the ignition location indicates that narrowing down the ignition location in TWA 800 may be possible. However, the complexity of the combustion and structural failure processes in the actual center wing tank mandates extremely careful consideration of the uncertainties that enter into this process
Characterisation of the Muscle Protein Synthetic Response to Resistance Exercise in Healthy Adults: A Systematic Review and Exploratory Meta-Analysis
Background and Objective: The rate of skeletal muscle protein synthesis (MPS) is the principal driving force underpinning the muscular adaptive response to resistance exercise (RE). This study aims to consolidate the literature, characterise MPS response to RE, and assess the impact of key covariates. Methods: Five electronic databases (PubMed (Medline), Web of Science, Embase, Sport Discus, and Cochrane Library) were searched for controlled trials that assessed the MPS response to RE in healthy, adult humans, postabsorptive state. Individual study and random-effects meta-analysis arewere used to inform the effects of RE and covariates on MPS. Results from 79 controlled trials with 237 participants were analysed. Results: Analysis of the pooled effects revealed robust increases in MPS following RE (weighted mean difference (WMD): 0.032% h−1, 95% CI: [0.024, 0.041] % h−1, I2 = 92%, k = 37, P<0.001). However, the magnitude of the increase in MPS was lower in older adults (>50 y: WMD: 0.015% h−1, 95% CI: [0.007, 0.022] % h−1, I2 = 76%, k = 12, P=0.002) compared to younger adults (<35 y: WMD: 0.041% h−1, 95% CI: [0.030, 0.052] % h−1, I2 = 88%, k = 25, P<0.001). Individual studies have reported that the temporal proximity of the RE, muscle group, muscle protein fraction, RE training experience, and the loading parameters of the RE (i.e., intensity, workload, and effort) appeared to affect the MPS response to RE, whereas sex or type of muscle contraction does not. Conclusion: A single bout of RE can sustain measurable increases in postabsorptive MPS soon after RE cessation and up to 48 h post-RE. However, there is substantial heterogeneity in the magnitude and time course of the MPS response between trials, which appears to be influenced by participants’ age and/or the loading parameters of the RE itself.Funder: Marigot Ltd; FundRef: https://doi.org/10.13039/10.13039/501100000821; Grant(s): IP_2019_087
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