QUANTITATIVE PHYTOCHEMICAL DETERMINATIONS AND IN-VITRO CYTOTOXIC ACTIVITY OF MEDICINAL PLANTS

The present study evaluates in-vitro cytotoxic activity of active extracts of medicinal plants. It evaluates anti-cancer activity of most active extracts of I. pes-caprae and C. roseus. This study focuses on the total phenol content and the total flavanoid content of the plant and searches into its medicinal potency based on the total phenol and total flavanoid content. The anti-cancer activity of the extract is found to be more significant than one another. The cytotoxic activity of Ipomoea pes-caprae and C. roseus showed better results. Methanol extracts of aerial and root of Ipomoea pes-caprae possess maximum anticancer activity is found to be 61.77% and 65.55%. Chloroform extract of Catharanthus roseus root was also active against MCF- 7 cells by exhibiting 64.34% of activity. These plants may be a source of new antibiotic compounds.These findings enriches our knowledge of the chemical constituents that are responsible for the medicinal uses of the plant and the anti-cancer potential of selected plants