An Overview of the Kauffman Firm Survey: Results From 2009 Business Activities

Highlights findings from longitudinal data on new businesses' performance since 2004 as well as new firms founded in 2009, including trends in customer payment problems and loan denials, financial injections, and sources of comparative advantage

Casting a Wide Net: Online Activities of Small and New Businesses in the United States

Examines trends in businesses' use of Web sites and e-mail, online sales, and outcomes of such online activities by industry, age and size of firm, and owners' race/ethnicity, gender, location, and education

An Overview of the Kauffman Firm Survey: Results From 2010 Business Activities

Examines longitudinal data on new businesses' survival and performance since 2004 as well as new firms founded in 2010, including trends in slow or lost sales, predictability of business conditions, credit availability, and product or service innovation

The New Contact Binary GSC 2414-0797

Original article can be found at: http://www.konkoly.hu/ibvs/GSC 2414-0797 has a contact binary star type light curve, a 0.4 magnitude brightness variation with a period 0.3406 days.Peer reviewe

An Overview of the Kauffman Firm Survey: Results From the 2004-2007 Data

Based on surveys conducted over four years, provides an overview of trends among U.S. firms established in 2004 and the business and owner characteristics associated with survival and growth, including level of innovation, structure, and financing

An Overview of the Kauffman Firm Survey: Results From the 2004-2008 Data

Presents findings from longitudinal data on new businesses founded in 2004, including financing structure; products, services, and innovations; and characteristics of the owners. Examines indicators of growth and survival and effects of the recession

A Hox regulatory network of hindbrain segmentation is conserved to the base of vertebrates

A defining feature governing head patterning of jawed vertebrates is a highly conserved gene regulatory network that integrates hindbrain segmentation with segmentally restricted domains of Hox gene expression. Although non-vertebrate chordates display nested domains of axial Hox expression, they lack hindbrain segmentation. The sea lamprey, a jawless fish, can provide unique insights into vertebrate origins owing to its phylogenetic position at the base of the vertebrate tree. It has been suggested that lamprey may represent an intermediate state where nested Hox expression has not been coupled to the process of hindbrain segmentation. However, little is known about the regulatory network underlying Hox expression in lamprey or its relationship to hindbrain segmentation. Here, using a novel tool that allows cross-species comparisons of regulatory elements between jawed and jawless vertebrates, we report deep conservation of both upstream regulators and segmental activity of enhancer elements across these distant species. Regulatory regions from diverse gnathostomes drive segmental reporter expression in the lamprey hindbrain and require the same transcriptional inputs (for example, Kreisler (also known as Mafba), Krox20 (also known as Egr2a)) in both lamprey and zebrafish. We find that lamprey hox genes display dynamic segmentally restricted domains of expression; we also isolated a conserved exonic hox2 enhancer from lamprey that drives segmental expression in rhombomeres 2 and 4. Our results show that coupling of Hox gene expression to segmentation of the hindbrain is an ancient trait with origin at the base of vertebrates that probably led to the formation of rhombomeric compartments with an underlying Hox code