Effect of low-cost white reflecting sling application on efficacy of phototherapy in healthy term neonates with non-hemolytic jaundice: A randomized controlled trial

Objective: The objective of this study was to evaluate the efficacy of white reflecting material (slings) hung from the sides of compact fluorescent lamp (CFL) phototherapy equipment in reducing the duration of phototherapy in healthy term neonates with non-hemolytic jaundice. Design: Randomized controlled trial. Setting: Postnatal ward of a tertiary level neonatal unit. Participants and Intervention: Healthy term neonates with non-hemolytic jaundice between 24 h and 14 days of age were randomly assigned to receive single surface phototherapy with (n=50) or without slings (n=50). Outcome Measure: Primary outcome was rate of reduction of serum bilirubin levels and secondary outcome was duration of phototherapy (hour) required. Results: Birth weight (2780±360 vs. 2790±260 g), gestation (38.22±1.0 vs. 38.08±0.90 week), and initial serum total bilirubin (17.36±1.06 vs. 16.96±1.20 mg/dL) were comparable between the two groups. There was a significant difference in the duration of phototherapy (mean ± standard deviation [SD]) between the sling (53.28±21.02 h) and no sling (62.88±20.22 h) groups (p=0.02). The irradiance of phototherapy equipment (μW/cm2/nm, mean±SD) was higher in sling group compared to no sling group (24.17±0.13 vs. 22.11±0.21). Conclusion: Hanging of white reflective sling on sides of CFL phototherapy equipment resulted in marginal increase in irradiance and reduction in the duration of phototherapy

Lipid profile abnormalities & 10 yr risk of CVD assessment among adult in North East India: A cross-sectional study

Background & objectives: In India, lifestyle changes have contributed to increase in the number of people suffering from lipid profile abnormalities, which is a major risk factor for coronary artery diseases. The present study was aimed to estimate the prevalence of lipid profile abnormalities and 10 yr risk of cardiovascular disease (CVD) among the adult population in west Tripura district and to study the association of lipid profile abnormalities and increased CVD risk with sociodemography, body mass index (BMI), hypertension, random blood sugar (RBS) and haemoglobin level. Methods: This cross-sectional study was conducted amongst 445 adults of 20 to 60 yr of age from a randomly selected block in west Tripura district. The 10 yr risk of CVD was estimated using the Framingham Risk Assessment Tool. Results: The study revealed that overall 83.4 per cent adult population had lipid profile abnormalities, with 22.2, 42 and 70.3 per cent of participants having hypercholesterolaemia, hypertriglyceridaemia and low high-density lipoprotein level, respectively. Gender (P=0.02) and BMI (P<0.001) were the significant determinants of dyslipidaemia. Only 3.8 per cent of participants had intermediate or high risk of CVD, with all of them being males. Gender, age, occupation and RBS were significantly associated with increased CVD risk. Interpretation & conclusions: The study revealed a high burden of lipid profile abnormalities in the study population, with males having more risk of CVD. Hence, periodic screening of lipid profile abnormalities and risk of CVD should be incorporated at the primary care level to combat the CVD epidemic in India