Group algebras and enveloping algebras with nonmatrix and semigroup identities

Let K be a field of positive characteristic p, let R be either a group algebra K[G] or a restricted enveloping algebra u(L), and let I be the augmentation ideal of R. We first characterize those R for which I satisfies a polynomial identity not satisfied by the algebra of all 2-by-2 matrices over K. Then we examine those R for which I satisfies a semigroup identity (that is, a polynomial identity which can be written as the difference of two monomials).Comment: 11 pages. Written in LaTeX2

A Presence of P____ and W__th

This body of work examines the involvement of association as it relates to our cultural interpretations of natural phenomena. Flowers and animals, both real and imagined, have been used as symbols for human morality since the beginning of human history. Two sources with which I drew inspiration from are medieval bestiaries and the Victorian practice of flower language. By combining elements from these references, I aim to pair this idea about the human need for classification with my own considerations about my identity. In combination, I also aim to highlight the responsibility that is intrinsic to curiosity. When faced with a mystery or something that does not give its information freely, what impulse will follow a desire for knowledge? In what way and through which criteria will something find itself classified? In what way does a flower become good or evil

Isolated States of America: The Impact of State Borders on Mobility and Regional Labor Market Adjustments

I document a new empirical pattern of internal mobility in the United States. Namely, county-to-county migration and commuting drop off discretely at state borders. People are three times as likely to move to a county 15 miles away, but in the same state, than to move to an equally distant county in a different state. These gaps remain even among neighboring counties or counties in the same commuting zone. This pattern is not explained by differences in county characteristics, is not driven by any particular demographic group, and is not explained by pecuniary costs such as differences in state occupational licensing, taxes, or transfer program generosity. However, county-to-county social connectedness (as measured by the number of Facebook linkages) follows a similar pattern. Although the patterns in social networks would be consistent with information frictions, nonpecuniary psychic costs, or behavioral biases such as a sate identity or home bias, the data suggest that state identity and home bias play an outsized role. This empirical pattern has real economic impacts. Building on existing methods, I show that employment in border counties adjusts more slowly after local economic shocks relative to interior counties. These counties also exhibit less in-migration and in-commuting, suggesting the lack of mobility leads to slower labor market adjustment

Accessibility and Perceived Value of Pre-Admission Clinical Contact Hours: Physical Therapy Clinician Perspectives

Purpose: This study analyzes the accessibility and perceived value of contact hours prior to a student\u27s acceptance to a professional physical therapy (PT) program from clinicians\u27 perspective. There is limited research regarding the effectiveness of pre-admission clinical contact hours in PT. The results may help the conversation on whether contact hours should be a requirement prior to acceptance into a program, and the impact the requirement may have on practicing clinicians. Methods: This study utilized an electronic survey sent to the chairpersons or Directors of Clinical Education of 1-2 accredited programs in each state (n=48) that has a PT program, asking them to distribute the survey to all clinical faculty affiliated with their respective programs. Follow up emails were sent to encourage participation. Survey items gathered information related to pre-admission clinical contact hour experiences and perceptions of usefulness, and limited participant demographic information. Results: Clinician respondents represented 34 states; 64% of the clinicians practiced in communities less than 250,000 people. Of the 553 respondents, 77% were female, and 42% of all respondents practiced in an outpatient orthopedic (hospital-based or private practice) setting. A majority of respondents (n=510; 95%) believed that pre-admission clinical contact hours were beneficial for students. The main benefits for students were getting a better understanding of the profession and determining career choice (n=284; 55%) and gaining experience/exposure to the profession (n=139; 27%). Clinicians cited their roles when working with pre-admission students as educating and answering questions (n=396; 75%), and ensuring students observe a variety of physical therapy settings and patient diagnoses (n=80; 15%). Some (n=29; 5%) believe contact hours were not beneficial stating, I feel it is another hoop to jump through for most students, and It takes up other clinical time that [professional PT] students could be benefitting from. Overall, clinicians believe that a quality contact experience is the result of exposure to a variety of PT settings and patients (n= 377; 36%) along with interacting with the PT and patients (n=355; 34%). Conclusion: Practicing clinicians suggest that pre-admission contact hours are beneficial in helping students understand the profession, choose a career in PT, and numerous other benefits. Future analyses will compare these results with 2 other studies, to determine if there is a correlation between clinician, faculty, and student perceptions of pre-admission clinical contact hours. Results may be useful to physical therapy programs as they formulate or revise admission requirements

The Covid-19 pandemic is linked to a ten percent increase in domestic violence cases across the country.

During the COVID-19 pandemic, millions of people across the world have been sheltering at home for several months, a shift which is sadly likely to mean a rise in domestic violence cases. After adjusting domestic violence call data for seasonal trends, Emily Leslie and Riley Wilson find that domestic violence increases by about ten percent compared to the same period in 2019 – an equivalent to nearly 1,400 additional cases across the US each day

Broad and thematic remodeling of the surfaceome and glycoproteome on isogenic cells transformed with driving proliferative oncogenes.

The cell surface proteome, the surfaceome, is the interface for engaging the extracellular space in normal and cancer cells. Here we apply quantitative proteomics of N-linked glycoproteins to reveal how a collection of some 700 surface proteins is dramatically remodeled in an isogenic breast epithelial cell line stably expressing any of six of the most prominent proliferative oncogenes, including the receptor tyrosine kinases, EGFR and HER2, and downstream signaling partners such as KRAS, BRAF, MEK, and AKT. We find that each oncogene has somewhat different surfaceomes, but the functions of these proteins are harmonized by common biological themes including up-regulation of nutrient transporters, down-regulation of adhesion molecules and tumor suppressing phosphatases, and alteration in immune modulators. Addition of a potent MEK inhibitor that blocks MAPK signaling brings each oncogene-induced surfaceome back to a common state reflecting the strong dependence of the oncogene on the MAPK pathway to propagate signaling. Cell surface protein capture is mediated by covalent tagging of surface glycans, yet current methods do not afford sequencing of intact glycopeptides. Thus, we complement the surfaceome data with whole cell glycoproteomics enabled by a recently developed technique called activated ion electron transfer dissociation (AI-ETD). We found massive oncogene-induced changes to the glycoproteome and differential increases in complex hybrid glycans, especially for KRAS and HER2 oncogenes. Overall, these studies provide a broad systems-level view of how specific driver oncogenes remodel the surfaceome and the glycoproteome in a cell autologous fashion, and suggest possible surface targets, and combinations thereof, for drug and biomarker discovery