The Convergence of Digital-Libraries and the Peer-Review Process

Pre-print repositories have seen a significant increase in use over the past fifteen years across multiple research domains. Researchers are beginning to develop applications capable of using these repositories to assist the scientific community above and beyond the pure dissemination of information. The contribution set forth by this paper emphasizes a deconstructed publication model in which the peer-review process is mediated by an OAI-PMH peer-review service. This peer-review service uses a social-network algorithm to determine potential reviewers for a submitted manuscript and for weighting the relative influence of each participating reviewer's evaluations. This paper also suggests a set of peer-review specific metadata tags that can accompany a pre-print's existing metadata record. The combinations of these contributions provide a unique repository-centric peer-review model that fits within the widely deployed OAI-PMH framework.Comment: Journal of Information Science [in press

Functionality of resistance gene Hero which controls plant root-infecting potato cyst nematodes, in leaves of tomato

The expression of host genomes is modified locally by root endoparasitic nematode secretions to induce the development of complex cellular structures referred as feeding sites. In compatible interactions, the feeding sites provide the environment and nutrients for the completion of the nematode's life cycle, whereas in an incompatible (resistant) interaction, the host immune system triggers a plant cell death programme, often in the form of a hypersensitive reaction, which restricts nematode reproduction. These processes have been studied in great detail in organ tissues normally infected by these nematodes: the roots. Here we show that host leaves can support a similar set of programmed developmental events in the potato cyst nematode Globodera rostochiensis life cycle that are typical of the root-invading nematodes. We also show that a gene-for-gene type specific disease resistance that is effective against potato cyst nematodes (PCN) in roots also operates in leaves: the expression of the resistance (R) gene Hero and members of its gene family in leaves correlates with the elicitation of a hypersensitive response only during the incompatible interaction. These findings, and the ability to isolate RNA from relevant parasitic stages of the nematode, may have significant implications for the identification of nematode factors involved in incompatible interactions