Impact des traitements en cancérologie sur les fonctions cognitives: Le point de vue des patients, leur attente et leur souhait de participer à des ateliers de rééducation cognitive

Introduction. Cancer and chemotherapy can have adverse effects on cognitive functions and quality of life of patients. We wanted to know the patients' view on these disorders, but also their expectations in terms of assessment and support. Methods and results. A survey was conducted in day care hospital among 551 patients from three cancer centers. Most of the patients were between 40 and 74 years and suffered from breast cancer. Eighty-four percent were treated with chemotherapy. Forty-one percent of patients report memory problems, 26% were affected by specific concentration disorders, and 19% of the attention. On the whole, 52% of patients report at least one of the previous cognitive impairment. Among these patients, 80% evoked that the support of these problems was essential and 70% were willing to participate in "workshops" to deal with these disorders. Conclusion. The cognitive impairment occurrence is a real problem for patients receiving chemotherapy and becomes a priority in the global management of their disease. Studies assessing a specific support of theses symptoms should be encouraged to help patients. © John Libbey Eurotext.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Impact of forest canopy on iodine, selenium and cesium atmospheric inputs on forest ecosystems

International audienceRadioisotopes 131I, 129I, 79Se, 134Cs and 137Cs are of health concerns in case of nuclear events. Due to their largeinteracting surface area by canopy, forests could impact the quantity and speciation of elements incoming from atmospheric inputs to the ground. This study investigated the atmospheric inputs of stable iodine, selenium and cesium,during one year in rainfall (twenty-seven monitored sites) as well as their canopy output in throughfall (fourteen sites)throughout France. Results showed that annual rainfall I concentrations were much higher than those of Se and Cs(mean = 1.57, 0.045 and 0.006 µg L‒1, respectively). Annual concentrations of I, Se and Na in rainfall were positivelycorrelated, suggesting common atmospheric scavenging mechanisms by rains and/or common source(s) for theseelements. Annual rainfall fluxes of elements varied greatly from one site to another (6.9-47.8, 0.20-1.86 and 0.02-0.11 gha‒1 yr.‒1 for I, Se and Cs respectively), mostly influenced by rainfall amounts. For most sites, concentrations and fluxes of elements in throughfall were higher than corresponding rainfall ones. Throughfall enrichments were shown to be mostly due to dry depositions for I and Se, and to leaching after canopy recretion for Cs. Iodine and selenium speciation (i.e., I‒, IO3‒, SeO32‒ and SeO42‒) was also determined.Results evidenced significant modifications of I and Se speciation from rainfall to throughfall, with a substantial increase of unidentified iodine and selenium compoundsproportions and a drastic decrease of inorganic I and Se species. Data issued from this work clarified spatial variationof iodine, selenium and cesium inputs and improved our understanding for cycle modelling in forest ecosystems

Atmospheric iodine, selenium and caesium depositions in France: I. Spatial and seasonal variations

International audienceThe spatial distribution and seasonal variations of atmospheric iodine (I), selenium (Se) and caesium (Cs) depositions remain unclear and this precludes adequate inputs for biogeochemical models. We quantified total concentrations and fluxes of these elements in rainfalls from 27 monitoring sites in France with contrasted climatic conditions; monthly measurements were taken over one year (starting in 2016/09). Since speciation of I and Se can impact their behaviour in the environment, analysis of their inorganic compounds was also conducted. Our results showed that annual I concentrations in rainfall were much higher than those of Se and Cs (annual means = 1.56, 0.044 and 0.005 μg L−1, respectively). The annual iodine concentrations were highly positively correlated with those of marine elements (i.e. Na, Cl and Mg), involving higher I concentrations under oceanic climate than for transition, continental and mountainous ones. Furthermore, common patterns were found between Se concentrations and both marine and terrestrial components consistent with the various sources of Se in atmosphere. The association of Cs with two anthropogenic components (i.e. NH4+ and NO3−) used in agriculture supports the hypothesis of its terrestrial origin (i.e. from atmospheric dusts) in rainfall. We found higher rainfall concentrations of I during the warmest months for all climates. However, no specific seasonal trend occurred for Se and Cs. On annual average, rainfall contained mostly unidentified selenium compounds (inorganic Se proportions = 25–54%) and equal proportions of inorganic and unidentified I compounds. Concentrations of iodate were higher under oceanic climate consistent with an iodine marine-origin

Impact of forest canopy on iodine, selenium and cesium atmospheric inputs on forest ecosystems

International audienceRadioisotopes 131I, 129I, 79Se, 134Cs and 137Cs are of health concerns in case of nuclear events. Due to their largeinteracting surface area by canopy, forests could impact the quantity and speciation of elements incoming from atmospheric inputs to the ground. This study investigated the atmospheric inputs of stable iodine, selenium and cesium,during one year in rainfall (twenty-seven monitored sites) as well as their canopy output in throughfall (fourteen sites)throughout France. Results showed that annual rainfall I concentrations were much higher than those of Se and Cs(mean = 1.57, 0.045 and 0.006 µg L‒1, respectively). Annual concentrations of I, Se and Na in rainfall were positivelycorrelated, suggesting common atmospheric scavenging mechanisms by rains and/or common source(s) for theseelements. Annual rainfall fluxes of elements varied greatly from one site to another (6.9-47.8, 0.20-1.86 and 0.02-0.11 gha‒1 yr.‒1 for I, Se and Cs respectively), mostly influenced by rainfall amounts. For most sites, concentrations and fluxes of elements in throughfall were higher than corresponding rainfall ones. Throughfall enrichments were shown to be mostly due to dry depositions for I and Se, and to leaching after canopy recretion for Cs. Iodine and selenium speciation (i.e., I‒, IO3‒, SeO32‒ and SeO42‒) was also determined.Results evidenced significant modifications of I and Se speciation from rainfall to throughfall, with a substantial increase of unidentified iodine and selenium compoundsproportions and a drastic decrease of inorganic I and Se species. Data issued from this work clarified spatial variationof iodine, selenium and cesium inputs and improved our understanding for cycle modelling in forest ecosystems

Impact of forest canopy on iodine, selenium and cesium atmospheric inputs on forest ecosystems

International audienceRadioisotopes 131I, 129I, 79Se, 134Cs and 137Cs are of health concerns in case of nuclear events. Due to their largeinteracting surface area by canopy, forests could impact the quantity and speciation of elements incoming from atmospheric inputs to the ground. This study investigated the atmospheric inputs of stable iodine, selenium and cesium,during one year in rainfall (twenty-seven monitored sites) as well as their canopy output in throughfall (fourteen sites)throughout France. Results showed that annual rainfall I concentrations were much higher than those of Se and Cs(mean = 1.57, 0.045 and 0.006 µg L‒1, respectively). Annual concentrations of I, Se and Na in rainfall were positivelycorrelated, suggesting common atmospheric scavenging mechanisms by rains and/or common source(s) for theseelements. Annual rainfall fluxes of elements varied greatly from one site to another (6.9-47.8, 0.20-1.86 and 0.02-0.11 gha‒1 yr.‒1 for I, Se and Cs respectively), mostly influenced by rainfall amounts. For most sites, concentrations and fluxes of elements in throughfall were higher than corresponding rainfall ones. Throughfall enrichments were shown to be mostly due to dry depositions for I and Se, and to leaching after canopy recretion for Cs. Iodine and selenium speciation (i.e., I‒, IO3‒, SeO32‒ and SeO42‒) was also determined.Results evidenced significant modifications of I and Se speciation from rainfall to throughfall, with a substantial increase of unidentified iodine and selenium compoundsproportions and a drastic decrease of inorganic I and Se species. Data issued from this work clarified spatial variationof iodine, selenium and cesium inputs and improved our understanding for cycle modelling in forest ecosystems

Atmospheric iodine, selenium and caesium depositions in France: II. Influence of forest canopies

International audienc

Molecular Cloning and Characterization of Apricot Fruit Polyphenol Oxidase

A reverse transcriptase-polymerase chain reaction experiment was done to synthesize a homologous polyphenol oxidase (PPO) probe from apricot (Prunus armeniaca var Bergeron) fruit. This probe was further used to isolate a full-length PPO cDNA, PA-PPO (accession no. AF020786), from an immature-green fruit cDNA library. PA-PPO is 2070 bp long and contains a single open reading frame encoding a PPO precursor peptide of 597 amino acids with a calculated molecular mass of 67.1 kD and an isoelectric point of 6.84. The mature protein has a predicted molecular mass of 56.2 kD and an isoelectric point of 5.84. PA-PPO belongs to a multigene family. The gene is highly expressed in young, immature-green fruit and is turned off early in the ripening process. The ratio of PPO protein to total proteins per fruit apparently remains stable regardless of the stage of development, whereas PPO specific activity peaks at the breaker stage. These results suggest that, in addition to a transcriptional control of PPO expression, other regulation factors such as translational and posttranslational controls also occur