Deep-inelastic production of heavy quarks

Deep-inelastic production of heavy quarks at HERA, especially charm, is an excellent signal to measure the gluon distribution in the proton at small $x$ values. By measuring various differential distributions of the heavy quarks this reaction permits additional more incisive QCD analyses due to the many scales present. Furthermore, the relatively small mass of the charm quark, compared to the typical momentum transfer $Q$, allows one to study whether and when to treat this quark as a parton. This reaction therefore sheds light on some of the most fundamental aspects of perturbative QCD. We discuss the above issues and review the feasibility of their experimental investigation in the light of a large integrated luminosity.Comment: 10 pages, uses epsfig.sty, five ps figures included. To appear in the proceedings of the workshop Future Physics at HERA, eds. G. Ingelman, A. De Roeck and R. Klanner, DESY, Hamburg, 199

The Heavy-Flavour Contribution to Proton Structure

We present theoretical and experimental considerations pertaining to deeply inelastic heavy-flavour production at HERA. The various theoretical uncertainties in the cross section calculation are discussed. Cuts are imposed to determine the fraction of charm production accessible to the detectors. The production of charm at asymptotic $Q^2$ and bottom production are also covered. Experimental aspects include current charm production data analysis and prospects for future analyses including anticipated high precision and distinguishing photon-gluon fusion charm events from excitation from the charm parton density. The feasibility of measuring $F_2^{b\overline b}(x,Q^2)$ is investigated.Comment: 22 total pages with 16 figures. To appear in abbreviated form in the proceedings of the workshop ``Future Physics at HERA'', DESY, Hamburg, 199

A protocol for light therapy in bipolar disorder

BACKGROUND There is no national protocol for the use of light therapy in bipolar depression. AIM The chronotherapy collaboration group of the Foundation for Bipolar Disorders intended to write a protocol for light therapy in bipolar depressive episodes. METHOD Narrative review of several systematic reviews, two clinician’s guides and deliberation with the sub-commission Guidelines of the Dutch Ophthalmologic Society. RESULTS The following indication was established: depressive episode, with or without seasonal features, in bipolar I or II disorder, including subsyndromal (depressive) seasonal complaints. The list of relative contra-indications (pre-existent retinal illnesses, systemic illnesses with effect on the retina and use of photosensitive medication) was shortened. In this case the medical professional discusses the possibility of an ophthalmologic consultation with the patient. Use of a mood stabilizer/antimanic medication in order to prevent mania or a mixed episode is only necessary in a depressive episode in bipolar I, but not in bipolar II disorder. Standard treatment is 10.000 lux white light during 30 minutes in the morning. CONCLUSION There is sufficient evidence to propose light therapy in a bipolar depressive episode with or without seasonal features.</p

A new automated method for the determination of the Total Antioxidant Capacity (TAC) of human plasma, based on the crocin bleaching assay

BACKGROUND: Antioxidant molecules, which scavenge free radical species to prevent or delay oxidative damage of important macromolecules, membrane lipids and lipoproteins, are prevalent in plasma and other biological fluids. Among them, bilirubin, uric acid and protein thiols are the major endogenous antioxidants, while vitamins C and E, as well as a number of food-derived (poly)aromatic substances, belonging to stilbens, flavonoids and phenolic acids, are the main classes of nutritional antioxidants. Assays for total antioxidant capacity in plasma differ in their type of oxidation source, target and measurement used to detect the oxidized product. METHODS: In the present work we present an automated assay for the estimation of blood total antioxidant capacity (TAC assay), based on the crocin bleaching (oxidation) method. This method was adapted on a modern autoanalyzer, was linear over a wide range of values (0–3 mmol/L), and performed using an end point measurement. RESULTS: The TAC method presented a linear correlation with another automated commercial Total Antioxidant Status (TAS) test. Detection of the interference of different metabolites revealed a significant participation of TAC from uric acid, bilirubin, albumin, a minor interference from ascorbic acid, and no interference from hemoglobin. TAC was not modified by two freeze/thawing cycles, and was stable in samples stored at room temperature for 4 hours. K-EDTA and heparin were the best anticoagulants, while citrate decreased TAC by 20%. Reference values derived from samples of normal blood donors was 1.175 ± 0.007 mmol/L (mean ± SEM), while a diet rich in antioxidants more than doubled this value. CONCLUSIONS: The proposed TAC assay, is fully automated, stable and reliable, and could be of value in the estimation of the AC of plasma. It is further proposed to calculate the antioxidant capacity of plasma after a subtraction of all interference deriving from endogenous and/or exogenous metabolites. The antioxidant capacity of plasma thus calculated can be used as a useful indicator of the antioxidant value of foods and beverages in the daily diet

Charm quark and D^* cross sections in deeply inelastic scattering at DESY HERA

A next-to-leading order Monte Carlo program for the calculation of heavy quark cross sections in deeply inelastic scattering is described. Concentrating on charm quark and D^*(2010) production at HERA, several distributions are presented and their variation with respect to charm quark mass, parton distribution set, and renormalization-factorization scale is studied.Comment: 15 pages including 8 figures. Uses Latex, Revtex, and psfig. References added - others updated. Several sentences/words added for clarity. Results/conclusions unchanged. To appear in Phys. Rev.

Prospects of Open Charm Production at GSI-FAIR and J-PARC

We present a detailed phenomenological study of the prospects of open charm physics at the future $\bar{p}p$ and $pp$ facilities GSI-FAIR and J-PARC, respectively. In particular, we concentrate on differential cross sections and the charge and longitudinal double-spin asymmetries at next-to-leading order accuracy. Theoretical uncertainties for the proposed observables are estimated by varying the charm quark mass and the renormalization and factorization scales.Comment: 11 pages, 13 figure

Deep-inelastic production of heavy quarks

Deep-inelastic production of heavy quarks at HERA, especially charm, is an excellent signal to measure the gluon distribution in the proton at small $x$ values. By measuring various differential distributions of the heavy quarks this reaction permits additional more incisive QCD analyses due to the many scales present. Furthermore, the relatively small mass of the charm quark, compared to the typical momentum transfer $Q$, allows one to study whether and when to treat this quark as a parton. This reaction therefore sheds light on some of the most fundamental aspects of perturbative QCD. We discuss the above issues and review the feasibility of their experimental investigation in the light of a large integrated luminosity