6 research outputs found

    Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

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    AbstractUnderstanding SARS-CoV-2 transmission in higher education settings is important to limit spread between students, and into at-risk populations. In this study, we sequenced 482 SARS-CoV-2 isolates from the University of Cambridge from 5 October to 6 December 2020. We perform a detailed phylogenetic comparison with 972 isolates from the surrounding community, complemented with epidemiological and contact tracing data, to determine transmission dynamics. We observe limited viral introductions into the university; the majority of student cases were linked to a single genetic cluster, likely following social gatherings at a venue outside the university. We identify considerable onward transmission associated with student accommodation and courses; this was effectively contained using local infection control measures and following a national lockdown. Transmission clusters were largely segregated within the university or the community. Our study highlights key determinants of SARS-CoV-2 transmission and effective interventions in a higher education setting that will inform public health policy during pandemics.</jats:p

    From stages to phases, a theory of small developing country internationalization

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    Existing research in firm internationalization tends to adopt the perspective of relatively fixed country specific advantages and disadvantages. However, firms operating from small developing countries may experience rapidly shifting country-specific advantages due to industrial policy interventions. These changes influence the internal configuration and, ultimately, the internationalization paths of firms, a factor that is not captured by current theory. Using a combination of a country case study and nested multiple firm cases, data were collected on how organizations internationalized from Trinidad and Tobago, a small developing country. Unlike the relatively deterministic outward patterns predicted by existing theories, analysis revealed both evolutionary and co-evolutionary trajectories of development. These outcomes suggest that as a country moves to more open economic environment, network connections in the form of supplier and institutional relationships are of increased value for firms seeking to enter external markets
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