3,124 research outputs found

    Improving the clinical value and utility of CGM systems: issues and recommendations: a joint statement of the European Association for the Study of Diabetes and the American Diabetes Association Diabetes Technology Working Group

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    The first systems for continuous glucose monitoring (CGM) became available over 15 years ago. Many then believed CGM would revolutionize the use of intensive insulin therapy in diabetes; however, progress toward that vision has been gradual. Although increasing, the proportion of individuals using CGM rather than conventional systems for self-monitoring of blood glucose on a daily basis is still low in most parts of the world. Barriers to uptake include cost, measurement reliability (particularly with earlier-generation systems), human factors issues, lack of a standardized format for displaying results, and uncertainty on how best to use CGM data to make therapeutic decisions. This Scientific Statement makes recommendations for systemic improvements in clinical use and regulatory (pre- and postmarketing) handling of CGM devices. The aim is to improve safety and efficacy in order to support the advancement of the technology in achieving its potential to improve quality of life and health outcomes for more people with diabetes

    Improving the clinical value and utility of CGM systems: issues and recommendations : a joint statement of the European Association for the Study of Diabetes and the American Diabetes Association Diabetes Technology Working Group

    Get PDF
    The first systems for continuous glucose monitoring (CGM) became available over 15 years ago. Many then believed CGM would revolutionise the use of intensive insulin therapy in diabetes; however, progress towards that vision has been gradual. Although increasing, the proportion of individuals using CGM rather than conventional systems for self-monitoring of blood glucose on a daily basis is still low in most parts of the world. Barriers to uptake include cost, measurement reliability (particularly with earlier-generation systems), human factors issues, lack of a standardised format for displaying results and uncertainty on how best to use CGM data to make therapeutic decisions. This scientific statement makes recommendations for systemic improvements in clinical use and regulatory (pre- and postmarketing) handling of CGM devices. The aim is to improve safety and efficacy in order to support the advancement of the technology in achieving its potential to improve quality of life and health outcomes for more people with diabetes

    Designing for Motivation, Engagement and Wellbeing in Digital Experience.

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    Research in psychology has shown that both motivation and wellbeing are contingent on the satisfaction of certain psychological needs. Yet, despite a long-standing pursuit in human-computer interaction (HCI) for design strategies that foster sustained engagement, behavior change and wellbeing, the basic psychological needs shown to mediate these outcomes are rarely taken into account. This is possibly due to the lack of a clear model to explain these needs in the context of HCI. Herein we introduce such a model: Motivation, Engagement and Thriving in User Experience (METUX). The model provides a framework grounded in psychological research that can allow HCI researchers and practitioners to form actionable insights with respect to how technology designs support or undermine basic psychological needs, thereby increasing motivation and engagement, and ultimately, improving user wellbeing. We propose that in order to address wellbeing, psychological needs must be considered within five different spheres of analysis including: at the point of technology adoption, during interaction with the interface, as a result of engagement with technology-specific tasks, as part of the technology-supported behavior, and as part of an individual's life overall. These five spheres of experience sit within a sixth, society, which encompasses both direct and collateral effects of technology use as well as non-user experiences. We build this model based on existing evidence for basic psychological need satisfaction, including evidence within the context of the workplace, computer games, and health. We extend and hone these ideas to provide practical advice for designers along with real world examples of how to apply the model to design practice

    Fluorescence of thermal control coatings on S0069 and A0114

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    Many of the thermal control surfaces exposed to the space environment during the 5.8 year LDEF mission experienced changes in fluorescence. All of the thermal control coatings flown on LDEF experiments S0069 and A0114 were characterized for fluorescence under ambient conditions. Some of the black coatings, having protective overcoats, appear bright yellow under ultraviolet exposure. Urethane based coatings exhibited emission spectra shifts toward longer wavelengths in the visible range. Zinc oxide pigment based coatings experienced a quenching of fluorescence, while zinc orthotitanate pigment based and other ceramic type coatings had no measurable fluorescence

    Supporting human autonomy in AI systems

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    Autonomy has been central to moral and political philosophy for millenia, and has been positioned as a critical aspect of both justice and wellbeing. Research in psychology supports this position, providing empirical evidence that autonomy is critical to motivation, personal growth and psychological wellness. Responsible AI will require an understanding of, and ability to effectively design for, human autonomy (rather than just machine autonomy) if it is to genuinely benefit humanity. Yet the effects on human autonomy of digital experiences are neither straightforward nor consistent, and are complicated by commercial interests and tensions around compulsive overuse. This multi-layered reality requires an analysis that is itself multidimensional and that takes into account human experience at various levels of resolution. We borrow from HCI and psychological research to apply a model (“METUX”) that identifies six distinct spheres of technology experience. We demonstrate the value of the model for understanding human autonomy in a technology ethics context at multiple levels by applying it to the real-world case study of an AI-enhanced video recommender system. In the process we argue for the following three claims: 1) There are autonomy-related consequences to algorithms representing the interests of third parties, and they are not impartial and rational extensions of the self, as is often perceived; 2) Designing for autonomy is an ethical imperative critical to the future design of responsible AI; and 3) Autonomy-support must be analysed from at least six spheres of experience in order to approriately capture contradictory and downstream effects

    A New, Bright, Short-Period, Emission Line Binary in Ophiuchus

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    The 11th magnitude star LS IV-08°3 has been classified previously as an OB star in the Luminous Stars survey, or alternatively as a hot subdwarf. It is actually a binary star. We present spectroscopy, spectroscopic orbital elements, and time-series photometry from observations made at the Kitt Peak National Observatory 2.1 m, Steward Observatory 2.3 m, MDM Observatory 1.3 m and 2.4 m, Hobby-Eberly 9.2 m, and Michigan State University 0.6 m telescopes. The star exhibits emission of varying strength in the cores of H and He I absorption lines. Emission is also present at 4686 Å (He II) and near 4640/4650 Å (N III/C III). Time-series spectroscopy collected from 2005 July to 2007 June shows coherent, periodic radial velocity variations of the Hα line, which we interpret as orbital motion with a period of 0.1952894(10) days. High-resolution spectra show that there are two emission components, one broad and one narrow, moving in antiphase, as might arise from an accretion disk and the irradiated face of the mass donor star. Less coherent, low-amplitude photometric variability is also present on a timescale similar to the orbital period. Diffuse interstellar bands indicate considerable reddening, which however is consistent with a distance of ~100-200 pc. The star is the likely counterpart of a weak ROSAT X-ray source, whose properties are consistent with accretion in a cataclysmic variable (CV) binary system. We classify LS IV-08°3 as a new member of the UX UMa subclass of CV stars

    The potential impact of Ocean Thermal Energy Conversion (OTEC) on fisheries

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    The commercial development of ocean thermal energy conversion (OTEC) operations will involve some environmental perturbations for which there is no precedent experience. The pumping of very large volumes of warm surface water and cold deep water and its subsequent discharge will result in the impingement, entrainment, and redistribution of biota. Additional stresses to biota will be caused by biocide usage and temperature depressions. However, the artificial upwelling of nutrients associated with the pumping of cold deep water, and the artificial reef created by an OTEC plant may have positive effects on the local environment. Although more detailed information is needed to assess the net effect of an OTEC operation on fisheries, certain assumptions and calculations are made supporting the conclusion that the potential risk to fisheries is not significant enough to deter the early development of IDEe. It will be necessary to monitor a commercial-scale plant in order to remove many of the remaining uncertainties. (PDF file contains 39 pages.
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