4,410 research outputs found
The Effects Of Student Response Systems On Performance And Satisfaction: An Investigation In A Tax Accounting Class
Does the use of student response systems (clickers) in the classroom increase student performance on exams? Do students perceive a benefit to using clickers in the classroom? This study investigates the effect of student response systems on accounting students’ learning outcome and perceived satisfaction. Results show that, though the use of clickers may not always help students do better on exams, clickers are a useful pedagogical tool that can help students pay attention in class and be more involved in a learning friendly environment
Hyperparameter Learning for Conditional Kernel Mean Embeddings with Rademacher Complexity Bounds
Conditional kernel mean embeddings are nonparametric models that encode
conditional expectations in a reproducing kernel Hilbert space. While they
provide a flexible and powerful framework for probabilistic inference, their
performance is highly dependent on the choice of kernel and regularization
hyperparameters. Nevertheless, current hyperparameter tuning methods
predominantly rely on expensive cross validation or heuristics that is not
optimized for the inference task. For conditional kernel mean embeddings with
categorical targets and arbitrary inputs, we propose a hyperparameter learning
framework based on Rademacher complexity bounds to prevent overfitting by
balancing data fit against model complexity. Our approach only requires batch
updates, allowing scalable kernel hyperparameter tuning without invoking kernel
approximations. Experiments demonstrate that our learning framework outperforms
competing methods, and can be further extended to incorporate and learn deep
neural network weights to improve generalization.Comment: Best Student Machine Learning Paper Award Winner at ECML-PKDD 2018
(European Conference on Machine Learning and Principles and Practice of
Knowledge Discovery in Databases
System FC with Explicit Kind Equality (extended version)
System FC, the core language of the Glasgow Haskell Compiler, is an explicitly-typed variant of System F with first-class type equality proofs called coercions. This extensible proof system forms the foundation for type system extensions such as type families (type- level functions) and Generalized Algebraic Datatypes (GADTs). Such features, in conjunction with kind polymorphism and datatype promotion, support expressive compile-time reasoning.
However, the core language lacks explicit kind equality proofs. As a result, type-level computation does not have access to kind- level functions or promoted GADTs, the type-level analogues to expression-level features that have been so useful. In this paper, we eliminate such discrepancies by introducing kind equalities to System FC. Our approach is based on dependent type systems with heterogeneous equality and the “Type-in-Type” axiom, yet it preserves the metatheoretic properties of FC. In particular, type checking is simple, decidable and syntax directed. We prove the preservation and progress theorems for the extended language
System FC with Explicit Kind Equality
System FC, the core language of the Glasgow Haskell Compiler, is an explicitly-typed variant of System F with first-class type equality proofs called coercions. This extensible proof system forms the foundation for type system extensions such as type families (type- level functions) and Generalized Algebraic Datatypes (GADTs). Such features, in conjunction with kind polymorphism and datatype promotion, support expressive compile-time reasoning.
However, the core language lacks explicit kind equality proofs. As a result, type-level computation does not have access to kind- level functions or promoted GADTs, the type-level analogues to expression-level features that have been so useful. In this paper, we eliminate such discrepancies by introducing kind equalities to System FC. Our approach is based on dependent type systems with heterogeneous equality and the “Type-in-Type” axiom, yet it preserves the metatheoretic properties of FC. In particular, type checking is simple, decidable and syntax directed. We prove the preservation and progress theorems for the extended language
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Targeting RyR Activity Boosts Antisense Exon 44 and 45 Skipping in Human DMD Skeletal or Cardiac Muscle Culture Models.
Systemic delivery of antisense oligonucleotides (AO) for DMD exon skipping has proven effective for reframing DMD mRNA, rescuing dystrophin expression, and slowing disease progression in animal models. In humans with Duchenne muscular dystrophy treated with AOs, low levels of dystrophin have been induced, and modest slowing of disease progression has been observed, highlighting the need for improved efficiency of human skipping drugs. Here, we demonstrate that dantrolene and Rycals S107 and ARM210 potentiate AO-mediated exon skipping of exon 44 or exon 45 in patient-derived myotube cultures with appropriate mutations. Further, dantrolene is shown to boost AO-mediated exon skipping in patient-derived, induced cardiomyocyte cultures. Our findings further validate the ryanodine receptors (RyR) as the likely target responsible for exon skip boosting and demonstrate potential applicability beyond exon 51 skipping. These data provide preclinical support of dantrolene trial as an adjuvant to AO-mediated exon-skipping therapy in humans and identify a novel Rycal, ARM210, for development as a potential exon-skipping booster. Further, they highlight the value of mutation-specific DMD culture models for basic discovery, preclinical drug screening and translation of personalized genetic medicines
Business Students Perception Of University Library Service Quality And Satisfaction
The main purpose of this study is to examine the college students perception of library services, and to what extent the quality of library services influences students satisfaction. The findings depict the relationship between academic libraries and their users in todays digital world and identify critical factors that may sustain a viable library-user relationship on campus
Metrology Camera System of Prime Focus Spectrograph for Subaru Telescope
The Prime Focus Spectrograph (PFS) is a new optical/near-infrared multi-fiber
spectrograph designed for the prime focus of the 8.2m Subaru telescope. PFS
will cover a 1.3 degree diameter field with 2394 fibers to complement the
imaging capabilities of Hyper SuprimeCam. To retain high throughput, the final
positioning accuracy between the fibers and observing targets of PFS is
required to be less than 10um. The metrology camera system (MCS) serves as the
optical encoder of the fiber motors for the configuring of fibers. MCS provides
the fiber positions within a 5um error over the 45 cm focal plane. The
information from MCS will be fed into the fiber positioner control system for
the closed loop control. MCS will be located at the Cassegrain focus of Subaru
telescope in order to to cover the whole focal plane with one 50M pixel Canon
CMOS camera. It is a 380mm Schmidt type telescope which generates a uniform
spot size with a 10 micron FWHM across the field for reasonable sampling of
PSF. Carbon fiber tubes are used to provide a stable structure over the
operating conditions without focus adjustments. The CMOS sensor can be read in
0.8s to reduce the overhead for the fiber configuration. The positions of all
fibers can be obtained within 0.5s after the readout of the frame. This enables
the overall fiber configuration to be less than 2 minutes. MCS will be
installed inside a standard Subaru Cassgrain Box. All components that generate
heat are located inside a glycol cooled cabinet to reduce the possible image
motion due to heat. The optics and camera for MCS have been delivered and
tested. The mechanical parts and supporting structure are ready as of spring
2016. The integration of MCS will start in the summer of 2016.Comment: 11 pages, 15 figures. SPIE proceeding. arXiv admin note: text overlap
with arXiv:1408.287
Flaw investigation in a multi-layered, multi-material composite: Using air-coupled ultrasonic resonance imaging
Ceramic tiles are the main ingredient of a multi-material, multi-layered composite being considered for the modernization of tank armors. The high stiffness, low attenuation, and precise dimensions of these uniform tiles make them remarkable resonators when driven to vibrate. Defects in the tile, during manufacture or after usage, are expected to change the resonance frequencies and resonance images of the tile. The comparison of the resonance frequencies and resonance images of a pristine tile/lay-up to a defective tile/lay-up will thus be a quantitative damage metric. By examining the vibrational behavior of these tiles and the composite lay-up with Finite Element Modeling and analytical plate vibration equations, the development of a new Nondestructive Evaluation technique is possible. This study examines the development of the Air-Coupled Ultrasonic Resonance Imaging technique as applied to a hexagonal ceramic tile and a multi-material, multi-layered composite
Limitations of symmetry in FE modeling: A comparison of fem and air-coupled resonance imaging
It has long been an accepted practice to use symmetry in Finite Element Modeling. Whenever modeling a large structure, we turn to symmetry in order to significantly reduce the model size and computation time. But is symmetry always the solution to long computation times, and is it always accurate? This study is aimed at modeling a whole ceramic tile and several possible symmetric models under several different loading cases and comparing them to each other and Air-Coupled Ultrasonic scans to determine if the Finite Element Models can accurately predict the vibrational resonance patterns. The reason for the accuracy or inaccuracy will also be examined. The understanding of the limitations of using symmetry to model large structures will be very useful in all future modeling
Flaw detection in a multi-material multi-layered composite: Using FEM and air-coupled UT
Ceramic tiles are the main ingredient of a multi‐layer multi‐material composite being considered for the modernization of tank armors. The high stiffness, low attenuation, and precise dimensions of these uniform tiles make them remarkable resonators when driven to vibrate. This study is aimed at modeling the vibration modes of the tiles and the composite lay‐up with finite element analysis and comparing the results with the resonance modes observed in air‐coupled ultrasonic excitation of the tiles and armor samples. Defects in the tile, during manufacturing and∕or after usage, are expected to change the resonance modes. The comparison of a pristine tile∕lay‐up and a defective tile∕lay‐up will thus be a quantitative damage metric. The understanding of the vibration behavior of the tile, both by itself and in the composite lay‐up, can provide useful guidance to the nondestructive evaluation of armor panels containing ceramic tiles
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