Discovery of ram-pressure stripped gas around an elliptical galaxy in Abell 2670

Studies of cluster galaxies are increasingly finding galaxies with spectacular one-sided tails of gas and young stars, suggestive of intense ram-pressure stripping. These so-called "jellyfish" galaxies typically have late-type morphology. In this paper, we present MUSE observations of an elliptical galaxy in Abell 2670 with long tails of material visible in the optical spectra, as well as blobs with tadpole-like morphology. The spectra in the central part of the galaxy reveals a stellar component as well as ionized gas. The stellar component does not have significant rotation, while the ionized gas defines a clear star-forming gas disk. We argue, based on deep optical images of the galaxy, that the gas was most likely acquired during a past wet merger. It is possible that the star-forming blobs are also remnants of the merger. In addition, the direction and kinematics of the one-sided ionized tails, combined with the tadpole morphology of the star-forming blobs, strongly suggests that the system is undergoing ram pressure from the intracluster medium. In summary, this paper presents the discovery of a post-merger elliptical galaxy undergoing ram pressure stripping.Comment: 6 pages, 5 figures, accepted for publication in ApJ

Subject-Independent Detection of Yes/No Decisions Using EEG Recordings During Motor Imagery Tasks: A Novel Machine-Learning Approach with Fine-Graded EEG Spectrum

The classification of sensorimotor rhythms in electroencephalography signals can enable paralyzed individuals, for example, to make yes/no decisions. In practice, these approaches are hard to implement due to the variability of electroencephalography signals between and within subjects. Therefore, we report a novel and fast machine learning model, meeting the need for efficiency and reliability as well as low calibration and training time. Our model extracts finely graded frequency bands from motor imagery electroencephalography data by using power spectral density and training a random forest algorithm for classification. The goal was to create a non-invasive generalizable method by training the algorithm with subject-independent EEG data. We evaluate our approach using one of the currently largest publicly available electroencephalography datasets. With a balanced accuracy of 73.94%, our novel algorithm outperforms other state-of-the-art non-subject-dependent algorithms

Impact of industry 4.0 tools in logistics : case analysis in Colombia

Este trabajo presenta un análisis de los escenarios de aplicación de las herramientas de la industria 4.0 (impresión 3D, computación en la nube, realidad aumentada (AR), Internet de las cosas (IoT) y robots autónomos) y su impacto en la logística a escala internacional con énfasis en el contexto colombiano, encontrando beneficios en términos de reducción de costos y tiempos, así como optimización de recursos y el aporte de dichas herramientas en la toma de decisiones dentro de las organizaciones. También se realizó un análisis de 43 empresas a nivel internacional que han implementado herramientas 4.0, señalando sus principales áreas de aplicación. Finalmente, se identificaron las áreas potenciales de aplicación de cada herramienta en Colombia, teniendo en cuenta las diferencias entre su nivel de desarrollo a nivel mundial y en el país.This work presents an analysis of the application scenarios of industry 4.0 tools (3D printing, cloud computing, augmented reality (AR), the internet of things (IoT) and autonomous robots) and their impact on logistics on an international scale with an emphasis in the Colombian context, finding benefits in terms of cost and time reduction as well as resource optimization and the contribution of said tools in decision-making within organizations. An analysis was also carried out of 43 companies at an international level that have implemented 4.0 tools, pointing out their main areas of application. Finally, the potential areas of application for each tool in Colombia were identified whilst keeping in mind the differences between their development level worldwide and in the country

Adhesion of Epiphany and AH Plus sealers to human root dentin treated with different solutions

This study evaluated comparatively the adhesion of Epiphany and AH Plus endodontic sealers to human root dentin treated with 1% NaOCl and 1% NaOCl+17% EDTA, using the push-out test. Sixty root cylinders obtained from maxillary canines had the canals prepared and were randomly assigned to 3 groups (n=20), according to root dentin treatment: GI - distilled water (control), GII - 1% NaOCl and GIII - 1% NaOCl+17% EDTA. Each group was divided into 2 subgroups (n=10) filled with either Epiphany or AH Plus. Bond strength push-out test data (kN) were obtained and analyzed statistically by ANOVA and Tukey&#39;s post-hoc test. There was statistically significant difference between sealers (AH Plus: 0.78 ± 0.13; Epiphany: 0.61 ± 0.19; p<0.01) and among root dentin treatments (distilled water: 0.58 ± 0.19; 1% NaOCl: 0.71 ± 0.12; 1% NaOCl+17% EDTA: 0.80 ± 0.17; p<0.05). In conclusion, AH Plus sealer presented greater adhesion to dentin than Epiphany, regardless of the treatment of root canal walls.O objetivo do presente estudo foi avaliar a adesividade do cimento Epiphany à dentina radicular previamente tratada com hipoclorito de sódio a 1% e EDTA a 17%, em comparação ao cimento AH Plus, pelo método do "push-out". Foram preparados sessenta cilindros de raízes de caninos superiores humanos que foram distribuídos em 3 grupos (n=20) de acordo com o tratamento da dentina: GI água destilada (controle), GII hipoclorito de sódio 1% e GIII EDTA 17 %. Esses grupos de corpos-de-prova foram distribuídos em 2 subgrupos para receber os cimentos obturadores a serem testados: Ephiphany e AH Plus. Foi realizado o teste do "push-out" e os resultados (em kN) foram analisados estatisticamente por ANOVA e o teste "post-hoc" de Tukey. A análise demonstrou diferença estatisticamente significativa entre os cimentos (AH Plus: 0,78 ± 0,13; Epiphany: 0,61 ± 0,19; p < 0,01) e entre as soluções testadas (água destilada: 0,58 ± 0,19; NaOCl: 0,71 ± 0,12; EDTA: 0,80 ± 0,17; p<0,05). Conclui-se que o cimento AH Plus apresentou valores de adesividade superiores aos obtidos pelo cimento Epiphany, independente do tratamento realizado nas paredes dos canais radiculares

Poly-L-Lysine-Based αGal-Glycoconjugates for Treating Anti-αGal IgE-Mediated Diseases

Mice; ImmunotherapyRatones; InmunoterapiaRatolins; ImmunoteràpiaAnti-αGal IgE antibodies mediate a spreading allergic condition known as αGal-syndrome (AGS). People exposed to hard tick bites are sensitized to αGal, producing elevated levels of anti-αGal IgE, which are responsible for AGS. This work presents an immunotherapy based on polymeric αGal-glycoconjugates for potentially treating allergic disorders by selectively inhibiting anti-αGal IgE antibodies. We synthesized a set of αGal-glycoconjugates, based on poly-L-lysine of different degrees of polymerization (DP1000, DP600, and DP100), to specifically inhibit in vitro the anti-αGal IgE antibodies in the serum of αGal-sensitized patients (n=13). Moreover, an animal model for αGal sensitization in GalT-KO mice was developed by intradermal administration of hard tick’ salivary gland extract, mimicking the sensitization mechanism postulated in humans. The in vitro exposure to all polymeric glycoconjugates (5-10-20-50-100 µg/mL) mainly inhibited anti-αGal IgE and IgM isotypes, with a lower inhibition effect on the IgA and IgG, respectively. We demonstrated a differential anti-αGal isotype inhibition as a function of the length of the poly-L-lysine and the number of αGal residues exposed in the glycoconjugates. These results defined a minimum of 27 αGal residues to inhibit most of the induced anti-αGal IgE in vitro. Furthermore, the αGal-glycoconjugate DP1000-RA0118 (10 mg/kg sc.) showed a high capacity to remove the anti-αGal IgE antibodies (≥75% on average) induced in GalT-KO mice, together with similar inhibition for circulating anti-αGal IgG and IgM. Our study suggests the potential clinical use of poly-L-lysine-based αGal-glycoconjugates for treating allergic disorders mediated by anti-αGal IgE antibodies

Adhesion of an endodontic sealer to dentin and gutta-percha: shear and push-out bond strength measurements and SEM analysis

The use of an adequate method for evaluation of the adhesion of root canal filling materials provides more reliable results to allow comparison of the materials and substantiate their clinical choice. The aims of this study were to compare the shear bond strength (SBS) test and push-out test for evaluation of the adhesion of an epoxy-based endodontic sealer (AH Plus) to dentin and gutta-percha, and to assess the failure modes on the debonded surfaces by means of scanning electron microscopy (SEM). Three groups were established (n=7): in group 1, root cylinders obtained from human canines were embedded in acrylic resin and had their canals prepared and filled with sealer; in group 2, longitudinal sections of dentin cylinders were embedded in resin with the canal surface smoothed and turned upwards; in group 3, gutta-percha cylinders were embedded in resin. Polyethylene tubes filled with sealer were positioned on the polished surface of the specimens (groups 2 and 3). The push-out test (group 1) and the SBS test (groups 2 and 3) were performed in an Instron universal testing machine running at crosshead speed of 1 mm/min. Means (±SD) in MPa were: G1 (8.8±1.13), G2 (5.9±1.05) and G3 (3.8±0.55). Statistical analysis by ANOVA and Student's t-test (a=0.05) revealed statistically significant differences (p<0.01) among the groups. SEM analysis showed a predominance of adhesive and mixed failures of AH Plus sealer. The tested surface affected significantly the results with the sealer reaching higher bond strength to dentin than to gutta-percha with the SBS test. The comparison of the employed methodologies showed that the SBS test produced significantly lower bond strength values than the push-out test, was skilful in determining the adhesion of AH Plus sealer to dentin and gutta-percha, and required specimens that could be easily prepared for SEM, presenting as a viable alternative for further experiments

Implementação das Práticas de Governança e Compliance da Lei de Responsabilidade das Estatais no Estado do Rio de Janeiro

O objetivo deste estudo é investigar o processo de implementação da Lei n. 13.303, que estabelece mecanismos de governança corporativa nas empresas estatais, públicas e sociedades de economia mista, no âmbito do estado do Rio de Janeiro. Para tanto, foi desenvolvida uma pesquisa de campo por meio da aplicação de questionários a quinze empresas estatais ativas cujo controle acionário pertence ao governo do estado do Rio de Janeiro. Subsequentemente, foram realizadas entrevistas semiestruturadas com 47 participantes do processo de implementação nessas estatais. O estudo sugere que, apesar de empenhadas na implementação da chamada Lei de Responsabilidade das Estatais, as empresas públicas controladas pelo estado do Rio de Janeiro encontravam sérias dificuldades na sua implementação, especialmente pela escassez de recursos financeiros e de pessoal, o que se dá não somente pela situação econômica geral, mas também pela crise financeira gerada pela corrupção sem medida de agentes públicos ocorrida no estado. O andamento da implementação foi agravado pela publicação tardia e o teor do decreto estadual de regulamentação, podendo gerar atraso e o não cumprimento integral das determinações da lei. O artigo inova ao estudar o processo de implementação durante sua ocorrência e antes da data-limite para entrada em vigor dos dispositivos da Lei 13.306/2016

Comparison of maximal heart rate using the prediction equations proposed by Karvonen and Tanaka

BACKGROUND: Equations for predicting maximal heart rate (HRmax) are widely used in exercise testing and for training prescription, but their efficacy remains controversial in the literature. OBJECTIVE: To compare maximal heart rate during cardiopulmonary exercise testing (CPET) using the prediction equations developed by Karvonen and Tanaka. METHODS: Of the 24,120 maximal treadmill graded exercise tests stored in the CEMAFE database from 1994 to 2006, 2047 HRmax values were analyzed, 1091 of which were from male and 956 from female sedentary subjects. These data were used as a gold standard to compare Karvonen's and Tanaka's prediction formulas. RESULTS: Mean measured maximal heart rates were 181.0 ± 14.0; 180.6 ± 13.0, and 180.8 ± 13.8 for men, women, and both genders combined, respectively. Likewise, mean values from Karvonen's equation were 182.0 ± 11.4; 183.7 ± 11.5, and 183.9 ± 11.7; and from Tanaka's, 182.0 ± 8.0; 182.6 ± 8.0, and 182.7 ± 8.2. Karvonen's and Tanaka's equations yielded the same correlation coefficients, as compared with measured maximal heart rate (r = 0.72). CONCLUSION: Karvonen's and Tanaka's equations are similar in predicting maximal heart rate and show good correlation with measured maximal heart rate.FUNDAMENTO: Fórmulas de predição da freqüência cardíaca máxima são amplamente utilizadas em serviços de ergometria e para prescrição de treinamento, contudo há controvérsia na literatura sobre a eficácia delas. OBJETIVO: Comparar a freqüência cardíaca máxima obtida pelo teste ergoespirométrico com as equações propostas por Karvonen e Tanaka. MÉTODOS: Dos 24.120 testes ergoespirométricos máximos, com protocolo de cargas crescentes, realizados em esteira rolante e armazenados no banco de dados do Cemafe, no período de 1994 a 2006, foram resgatados 1.091 resultados da freqüência cardíaca máxima de indivíduos sedentários do sexo masculino e 956 do feminino. Esses dados foram utilizados como padrão-ouro na comparação com as fórmulas de predição propostas por Karvonen e Tanaka. RESULTADOS: Os valores médios da freqüência cardíaca máxima medida foram: 181,0 ± 14,0, 180,6 ± 13,0 e 180,8 ± 13,8, para o sexo masculino, feminino e ambos os sexos, respectivamente. Seguindo o mesmo padrão, os valores para equação de Karvonen foram de 182,0 ± 11,4, 183,7 ± 11,5 e 183,9 ± 11,7; e os de Tanaka 182,0 ± 8,0, 182,6 ± 8,0 e 182,7 ± 8,2. A equação de Karvonen apresentou valores de correlação iguais à de Tanaka, quando comparadas com a freqüência cardíaca máxima medida, r = 0,72. CONCLUSÃO: As equações de Karvonen e Tanaka são semelhantes para predição da freqüência cardíaca máxima e apresentam boa correlação com a freqüência cardíaca máxima medida.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Metodista de PiracicabaUniversidade Santo AmaroUNIFESP, EPMSciEL