Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission

Funder: Addenbrooke's Charitable Trust, Cambridge University Hospitals; FundRef: http://dx.doi.org/10.13039/501100002927Significant differences exist in the availability of healthcare worker (HCW) SARS-CoV-2 testing between countries, and existing programmes focus on screening symptomatic rather than asymptomatic staff. Over a 3 week period (April 2020), 1032 asymptomatic HCWs were screened for SARS-CoV-2 in a large UK teaching hospital. Symptomatic staff and symptomatic household contacts were additionally tested. Real-time RT-PCR was used to detect viral RNA from a throat+nose self-swab. 3% of HCWs in the asymptomatic screening group tested positive for SARS-CoV-2. 17/30 (57%) were truly asymptomatic/pauci-symptomatic. 12/30 (40%) had experienced symptoms compatible with coronavirus disease 2019 (COVID-19)>7 days prior to testing, most self-isolating, returning well. Clusters of HCW infection were discovered on two independent wards. Viral genome sequencing showed that the majority of HCWs had the dominant lineage B∙1. Our data demonstrates the utility of comprehensive screening of HCWs with minimal or no symptoms. This approach will be critical for protecting patients and hospital staff

A Portrait of Fashion

Costume, portraiture and the presentation of the individual have been intimately linked throughout the history of art. While the face of the person portrayed is often still directly accessible to us, the details and significance of their dress can be less easy to comprehend. Lavishly illustrated throughout with paintings, drawings, photographs and other works of art, this beautiful publication is centred around 190 examples from the National Portrait Gallery’s Collection. Through these, the authors explore the purpose and original context of the dress in which the sitter was recorded – the damasks, satins, velvets and furs of Tudor and Stuart magnificence worn by Queen Elizabeth I and Charles I, but also the revolutionary simplicity of the cottons, linens and woollen cloth adopted by Mary Wollstonecraft, John Constable and John Clare. Packed with photographs that provide additional insights into the clothes worn by sitters in their portraits, and complemented by related material including fabric designs and jewellery, this authoritative guide looks in detail at one of the most fascinating aspects of many well-known images of the last 600 years