Tibial Plateau Fracture Following Low Energy Fall in the Rocky Mountains

Tibial plateau fractures are debilitating injuries. They can occurin younger individuals who sustain a high energy trauma or, withincreasing age, lesser degrees of trauma and underlying bone pathology such as osteoporosis, metabolic bone disease, and malignancy.1Outside these cases, tibial plateau fractures are relatively uncommon.However, these fractures can occur in healthy patients who have sustained direct trauma to the knee.Fractures of the tibial plateau often are classified according to theSchatzker or AO classification systems.2,3 These systems evaluate theinvolvement of both the medial and lateral plateaus, degree of comminution, extension into the joint, and displacement (both articularsurfaces and the relationship of the diaphysis to the metaphysis).Most tibial plateau fractures occur in the lateral aspect of the tibialplateau.1 The increased frequency of lateral fractures is due to themedial tibial plateau being able to resist higher weight-bearing loaddue to the presence of more cancellous bone. More importantly, thelateral plateau has more articular surface exposed during extensioncompared to the medial plateau, which increases likelihood of injury.4The standard of care for most displaced tibial plateau fracturesis surgical management with open reduction and internal fixation(ORIF).5 Conservative management, such as leg bracing, is an optionfor fractures that are nondisplaced or in patients too fragile for surgical intervention. In the senior population, a total knee arthroplasty(TKA) is a less common option. Tibial plateau fractures, particularlymedial tibial plateau fractures, caused by direct trauma in the elderly,non-osteoporotic population are uncommon.We present the case of an active male without overt risk for severefracture (10-year fracture risk of 10% via FRAX score) who wasworking to repair a trail in the Rocky Mountains. While other injurieswere more likely given the mechanism of injury and patient risk, thiscase highlighted the importance of considering tibial plateau fracture,even in atypical settings without significant risk. Improved awarenessof this mechanism of injury will lead to more accurate diagnosis andgreater post-injury management

Long-term optical/infrared variability in the quiescent X-ray transient V404 Cyg

We present the results of optical and infrared photometry of the quiescent X-ray transient V404 Cyg during the period 1992-2003. The ellipsoidal modulations extracted from the most complete databases (years 1992, 1998 and 2001) show unequal maxima and minima with relative strength varying from year to year although their peak to peak amplitudes remain roughly constant at 0.24+-0.01 magnitudes. Fast optical variations superimposed on the secondary star's double-humped ellipsoidal modulation were detected every year with a mean amplitude of ~0.07 mags. We have not found significant changes in the activity during this decade which indicates that this variability is probably not connected to the 1989 outburst. We have found periodicities in the 1998 and 2001 data near the 6 hr quasi-periodicity observed in 1992, although we interpret it as consequence of the appearance of a flare event almost every night. Significant variability is also present in the I and near infrared (J and K_short) bands and this decreases slightly or remains approximately constant at longer wavelengths. A cross correlation analysis shows that both the R and I emission are simultaneous down to 40 s.Comment: 13 pages, 11 figures; accepted for publication in MNRA

Microbiomes of Thalassia testudinum throughout the Atlantic Ocean, Caribbean Sea, and Gulf of Mexico are influenced by site and region while maintaining a core microbiome

Plant microbiomes are known to serve several important functions for their host, and it is therefore important to understand their composition as well as the factors that may influence these microbial communities. The microbiome of Thalassia testudinum has only recently been explored, and studies to-date have primarily focused on characterizing the microbiome of plants in a single region. Here, we present the first characterization of the composition of the microbial communities of T. testudinum across a wide geographical range spanning three distinct regions with varying physicochemical conditions. We collected samples of leaves, roots, sediment, and water from six sites throughout the Atlantic Ocean, Caribbean Sea, and the Gulf of Mexico. We then analyzed these samples using 16S rRNA amplicon sequencing. We found that site and region can influence the microbial communities of T. testudinum, while maintaining a plant-associated core microbiome. A comprehensive comparison of available microbial community data from T. testudinum studies determined a core microbiome composed of 14 ASVs that consisted mostly of the family Rhodobacteraceae. The most abundant genera in the microbial communities included organisms with possible plant-beneficial functions, like plant-growth promoting taxa, disease suppressing taxa, and nitrogen fixers

Physcomitrella patens DCL3 Is Required for 22–24 nt siRNA Accumulation, Suppression of Retrotransposon-Derived Transcripts, and Normal Development

Endogenous 24 nt short interfering RNAs (siRNAs), derived mostly from intergenic and repetitive genomic regions, constitute a major class of endogenous small RNAs in flowering plants. Accumulation of Arabidopsis thaliana 24 nt siRNAs requires the Dicer family member DCL3, and clear homologs of DCL3 exist in both flowering and non-flowering plants. However, the absence of a conspicuous 24 nt peak in the total RNA populations of several non-flowering plants has raised the question of whether this class of siRNAs might, in contrast to the ancient 21 nt microRNAs (miRNAs) and 21–22 nt trans-acting siRNAs (tasiRNAs), be an angiosperm-specific innovation. Analysis of non-miRNA, non-tasiRNA hotspots of small RNA production within the genome of the moss Physcomitrella patens revealed multiple loci that consistently produced a mixture of 21–24 nt siRNAs with a peak at 23 nt. These Pp23SR loci were significantly enriched in transposon content, depleted in overlap with annotated genes, and typified by dense concentrations of the 5-methyl cytosine (5 mC) DNA modification. Deep sequencing of small RNAs from two independent Ppdcl3 mutants showed that the P. patens DCL3 homolog is required for the accumulation of 22–24 nt siRNAs, but not 21 nt siRNAs, at Pp23SR loci. The 21 nt component of Pp23SR-derived siRNAs was also unaffected by a mutation in the RNA-dependent RNA polymerase mutant Pprdr6. Transcriptome-wide, Ppdcl3 mutants failed to accumulate 22–24 nt small RNAs from repetitive regions while transcripts from two abundant families of long terminal repeat (LTR) retrotransposon-associated reverse transcriptases were up-regulated. Ppdcl3 mutants also displayed an acceleration of leafy gametophore production, suggesting that repetitive siRNAs may play a role in the development of P. patens. We conclude that intergenic/repeat-derived siRNAs are indeed a broadly conserved, distinct class of small regulatory RNAs within land plants

A regional assessment of the ecological effects of chipping and mastication fuels reduction and forest restoration treatments.

Over the past several years, fire managers have increased their use of mastication treatments, the on-site disposal of shrubs and small-diameter trees through chipping and shredding. Mastication is a relatively untested management practice that alters the chemical and physical conditions of the forest floor and may influence vegetation regrowth and fuel development for years or decades. Eighteen sites were established across four ecosystems of the southern Rocky Mountains and the Colorado Plateau: lodgepole pine (Pinus contorta), mixed conifer (Pinus ponderosa, Pseudotsuga menziesii, Pinus flexilis, and Pinus contorta), ponderosa pine (Pinus ponderosa), and pinyon pine/juniper (Pinus edulis/Juniperus sp.). These sites were distributed across a wide geographic range throughout Colorado and represent treatments across several federal, state, and other land agencies. The sites were mulched between 2004 and 2006 and first measured in 2007 or 2008. The mechanical treatment added a substantial amount of 1-hr and 10-hr woody fuel

Dual leaching method for recovering silver and manganese from domestic manganifferrous silver deposits /

Bibliography: p. 8.Mode of access: Internet