Prospective memory functioning among ecstasy/polydrug users: evidence from the Cambridge Prospective Memory Test (CAMPROMPT)

Rationale: Prospective memory (PM) deficits in recreational drug users have been documented in recent years. However, the assessment of PM has largely been restricted to self-reported measures that fail to capture the distinction between event-based and time-based PM. The aim of the present study is to address this limitation. Objectives: Extending our previous research, we augmented the range laboratory measures of PM by employing the CAMPROMPT test battery to investigate the impact of illicit drug use on prospective remembering in a sample of cannabis only, ecstasy/polydrug and non-users of illicit drugs, separating event and time-based PM performance. We also administered measures of executive function and retrospective memory in order to establish whether ecstasy/polydrug deficits in PM were mediated by group differences in these processes. Results: Ecstasy/polydrug users performed significantly worse on both event and time-based prospective memory tasks in comparison to both cannabis only and non-user groups. Furthermore, it was found that across the whole sample, better retrospective memory and executive functioning was associated with superior PM performance. Nevertheless, this association did not mediate the drug-related effects that were observed. Consistent with our previous study, recreational use of cocaine was linked to PM deficits. Conclusions: PM deficits have again been found among ecstasy/polydrug users, which appear to be unrelated to group differences in executive function and retrospective memory. However, the possibility that these are attributable to cocaine use cannot be excluded

d+idd+id Holographic Superconductors

A holographic model of $d+id$ superconductors based on the action proposed by Benini, Herzog, and Yarom [arXiv:1006.0731] is studied. This model has a charged spin two field in an AdS black hole spacetime. Working in the probe limit, the normalizable solution of the spin two field in the bulk gives rise to a $d+id$ superconducting order parameter at the boundary of the AdS. We calculate the fermion spectral function in this\ superconducting background and confirm the existence of fermi arcs for non-vanishing Majorana couplings. By changing the relative strength $\gamma$ of the $d$ and $id$ condensations, the position and the size of the fermi arcs are changed. When $\gamma =1$, the spectrum becomes isotropic and the spectral function is s-wave like. By changing the fermion mass, the fermi momentum is changed. We also calculate the conductivity for these holographic $d+id$ superconductors where time reversal symmetry has been broken spontaneously. A non-vanishing Hall conductivity is obtained even without an external magnetic field.Comment: 24 pages,17 figures, Add more discussions on hall conductivity, two new figures, Matched with published versio

Strong interface-induced spin-orbit coupling in graphene on WS2

Interfacial interactions allow the electronic properties of graphene to be modified, as recently demonstrated by the appearance of satellite Dirac cones in the band structure of graphene on hexagonal boron nitride (hBN) substrates. Ongoing research strives to explore interfacial interactions in a broader class of materials in order to engineer targeted electronic properties. Here we show that at an interface with a tungsten disulfide (WS2) substrate, the strength of the spin-orbit interaction (SOI) in graphene is very strongly enhanced. The induced SOI leads to a pronounced low-temperature weak anti-localization (WAL) effect, from which we determine the spin-relaxation time. We find that spin-relaxation time in graphene is two-to-three orders of magnitude smaller on WS2 than on SiO2 or hBN, and that it is comparable to the intervalley scattering time. To interpret our findings we have performed first-principle electronic structure calculations, which both confirm that carriers in graphene-on-WS2 experience a strong SOI and allow us to extract a spin-dependent low-energy effective Hamiltonian. Our analysis further shows that the use of WS2 substrates opens a possible new route to access topological states of matter in graphene-based systems.Comment: Originally submitted version in compliance with editorial guidelines. Final version with expanded discussion of the relation between theory and experiments to be published in Nature Communication

The Pioneer Anomaly

Radio-metric Doppler tracking data received from the Pioneer 10 and 11 spacecraft from heliocentric distances of 20-70 AU has consistently indicated the presence of a small, anomalous, blue-shifted frequency drift uniformly changing with a rate of ~6 x 10^{-9} Hz/s. Ultimately, the drift was interpreted as a constant sunward deceleration of each particular spacecraft at the level of a_P = (8.74 +/- 1.33) x 10^{-10} m/s^2. This apparent violation of the Newton's gravitational inverse-square law has become known as the Pioneer anomaly; the nature of this anomaly remains unexplained. In this review, we summarize the current knowledge of the physical properties of the anomaly and the conditions that led to its detection and characterization. We review various mechanisms proposed to explain the anomaly and discuss the current state of efforts to determine its nature. A comprehensive new investigation of the anomalous behavior of the two Pioneers has begun recently. The new efforts rely on the much-extended set of radio-metric Doppler data for both spacecraft in conjunction with the newly available complete record of their telemetry files and a large archive of original project documentation. As the new study is yet to report its findings, this review provides the necessary background for the new results to appear in the near future. In particular, we provide a significant amount of information on the design, operations and behavior of the two Pioneers during their entire missions, including descriptions of various data formats and techniques used for their navigation and radio-science data analysis. As most of this information was recovered relatively recently, it was not used in the previous studies of the Pioneer anomaly, but it is critical for the new investigation.Comment: 165 pages, 40 figures, 16 tables; accepted for publication in Living Reviews in Relativit

Molecular Architectures of Trimeric SIV and HIV-1 Envelope Glycoproteins on Intact Viruses: Strain-Dependent Variation in Quaternary Structure

The initial step in target cell infection by human, and the closely related simian immunodeficiency viruses (HIV and SIV, respectively) occurs with the binding of trimeric envelope glycoproteins (Env), composed of heterodimers of the viral transmembrane glycoprotein (gp41) and surface glycoprotein (gp120) to target T-cells. Knowledge of the molecular structure of trimeric Env on intact viruses is important both for understanding the molecular mechanisms underlying virus-cell interactions and for the design of effective immunogen-based vaccines to combat HIV/AIDS. Previous analyses of intact HIV-1 BaL virions have already resulted in structures of trimeric Env in unliganded and CD4-liganded states at ∼20 Å resolution. Here, we show that the molecular architectures of trimeric Env from SIVmneE11S, SIVmac239 and HIV-1 R3A strains are closely comparable to that previously determined for HIV-1 BaL, with the V1 and V2 variable loops located at the apex of the spike, close to the contact zone between virus and cell. The location of the V1/V2 loops in trimeric Env was definitively confirmed by structural analysis of HIV-1 R3A virions engineered to express Env with deletion of these loops. Strikingly, in SIV CP-MAC, a CD4-independent strain, trimeric Env is in a constitutively “open” conformation with gp120 trimers splayed out in a conformation similar to that seen for HIV-1 BaL Env when it is complexed with sCD4 and the CD4i antibody 17b. Our findings suggest a structural explanation for the molecular mechanism of CD4-independent viral entry and further establish that cryo-electron tomography can be used to discover distinct, functionally relevant quaternary structures of Env displayed on intact viruses

Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen

Foot-and-mouth disease remains a major plague of livestock and outbreaks are often economically catastrophic. Current inactivated virus vaccines require expensive high containment facilities for their production and maintenance of a cold-chain for their activity. We have addressed both of these major drawbacks. Firstly we have developed methods to efficiently express recombinant empty capsids. Expression constructs aimed at lowering the levels and activity of the viral protease required for the cleavage of the capsid protein precursor were used; this enabled the synthesis of empty A-serotype capsids in eukaryotic cells at levels potentially attractive to industry using both vaccinia virus and baculovirus driven expression. Secondly we have enhanced capsid stability by incorporating a rationally designed mutation, and shown by X-ray crystallography that stabilised and wild-type empty capsids have essentially the same structure as intact virus. Cattle vaccinated with recombinant capsids showed sustained virus neutralisation titres and protection from challenge 34 weeks after immunization. This approach to vaccine antigen production has several potential advantages over current technologies by reducing production costs, eliminating the risk of infectivity and enhancing the temperature stability of the product. Similar strategies that will optimize host cell viability during expression of a foreign toxic gene and/or improve capsid stability could allow the production of safe vaccines for other pathogenic picornaviruses of humans and animals

Barriers to women entrepreneurship. Different methods, different results?

Building on research by Akehurst et al. (Serv Ind J 32:2489-2505, 2012), this study analysed internal and external factors in women entrepreneurship and linked these factors to the barriers that women face when starting businesses. To do so, two contrasting statistical techniques were used: PLS and QCA. After analysing results from each of these techniques, we observed that family duties and difficulties in obtaining financing (both internal and external) were the main factors related to barriers faced by women entrepreneurs

Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment

International audiencePURPOSE: Positron emission tomography (PET) imaging of brain amyloid load has been suggested as a core biomarker for Alzheimer's disease (AD). The aim of this study was to test the feasibility of using PET imaging with (18)F-AV-45 (florbetapir) in a routine clinical environment to differentiate between patients with mild to moderate AD and mild cognitive impairment (MCI) from normal healthy controls (HC). METHODS: In this study, 46 subjects (20 men and 26 women, mean age of 69.0 ± 7.6 years), including 13 with AD, 12 with MCI and 21 HC subjects, were enrolled from three academic memory clinics. PET images were acquired over a 10-min period 50 min after injection of florbetapir (mean ± SD of radioactivity injected, 259 ± 57 MBq). PET images were assessed visually by two individuals blinded to any clinical information and quantitatively via the standard uptake value ratio (SUVr) in the specific regions of interest, which were defined in relation to the cerebellum as the reference region. RESULTS: The mean values of SUVr were higher in AD patients (median 1.20, Q1-Q3 1.16-1.30) than in HC subjects (median 1.05, Q1-Q3 1.04-1.08; p = 0.0001) in the overall cortex and all cortical regions (precuneus, anterior and posterior cingulate, and frontal median, temporal, parietal and occipital cortex). The MCI subjects also showed a higher uptake of florbetapir in the posterior cingulate cortex (median 1.06, Q1-Q3 0.97-1.28) compared with HC subjects (median 0.95, Q1-Q3 0.82-1.02; p = 0.03). Qualitative visual assessment of the PET scans showed a sensitivity of 84.6% (95% CI 0.55-0.98) and a specificity of 38.1% (95% CI 0.18-0.62) for discriminating AD patients from HC subjects; however, the quantitative assessment of the global cortex SUVr showed a sensitivity of 92.3% and specificity of 90.5% with a cut-off value of 1.122 (area under the curve 0.894). CONCLUSION: These preliminary results suggest that PET with florbetapir is a safe and suitable biomarker for AD that can be used routinely in a clinical environment. However, the low specificity of the visual PET scan assessment could be improved by the use of specific training and automatic or semiautomatic quantification tools

Wellbeing indicators affecting female entrepreneurship in OECD countries

[EN] The objective of this research is to know which wellbeing indicators, such as work-life balance, educational level, income or job security, are related to the rate of female entrepreneurship in 29 OECD countries. In addition, these countries have been classified according to the motivation of the entrepreneur either by necessity or by opportunity. The empiric study is focused on 29 OECD countries covering the different geographic areas (Western Europe, Central and Eastern Europe, Middle East, etc.) Due to the fact that the sample is relatively small, it is essential to use a selective approach when selecting the causal conditions. To this end, fsQCA is the most appropriate methodology for such a small data set. A total of 5 variables have been used: an independent variable (female TEA ratio), and four dependent variables (work life balance, educational level, sustainable household income and job security). Data measuring female TEA ratio have been obtained from Global Entrepreneur Monitor (GEM in Global report, 2015) data base, while data measuring wellbeing dimensions were taken from the Better Life Index (OECD in How¿s life? Measuring wellbeing, 2015. http://www.oecdbetterlifeindex.org). The results of this piece of research show that countries with high sustainable household income together with high level of education achieves high female entrepreneurship ratio with both, a good work-life balance (despite of a high unemployment probability), or a high labour-personal imbalance (in this latter, with a low probability of unemployment).This work has been funded by the R + D project for emerging research groups with reference (GVA) GV/2016/078.Ribes-Giner, G.; Moya Clemente, I.; Cervelló Royo, RE.; Perelló Marín, MR. (2019). Wellbeing indicators affecting female entrepreneurship in OECD countries. Quality & Quantity. 53(2):915-933. https://doi.org/10.1007/s11135-018-0796-4S915933532Ahl, H., Nelson, T.: How policy positions women entrepreneurs: a comparative analysis of state discourse in Sweden and the United States. J. Bus. Ventur. 30(2), 273–291 (2015). https://doi.org/10.1016/j.jbusvent.2014.08.002Andersson, P.: Happiness and health: wellbeing among the self-employed. J. Socio-Econ. 37(1), 213–236 (2008). https://doi.org/10.1016/j.socec.2007.03.003Bardasi, E., Sabarwal, S., Terrell, K.: How do female entrepreneurs perform? Evidence from three developing regions. Small Bus. Econ. 37(4), 417–441 (2011). https://doi.org/10.1007/s11187-011-9374-zBergheim, S., Schneider, S., Giesel, B., Walter, N.: Measures of Wellbeing. There is More to it Than GDP. Deutsche Bank Research, Frankfurt (2006)Berglund, H.: Between cognition and discourse: phenomenology and the study of entrepreneurship. Int. J. Entrep. Behav. Res. 21(3), 472–488 (2015). https://doi.org/10.1108/IJEBR-12-2013-0210Bianchi, M., Parisi, V., Salvatore, R.: Female entrepreneurs: motivations and constraints. An Italian regional study. Int. J. Gend. Entrep. 8(3), 198–220 (2016). https://doi.org/10.1108/IJGE-08-2015-0029Bittencourt Marconatto, D.A., Barin-Cruz, L., Pozzebon, M., Poitras, J.E.: Developing sustainable business models within BOP contexts: mobilizing native capability to cope with government programs. J. Clean. Prod. 129, 735–748 (2016). https://doi.org/10.1016/j.jclepro.2016.03.038Boarini, R., Comola, M., Smith, C., Manchin, R., de Keulenaer, F.: What makes for a better life? The determinants of subjective well-being in OECD countries—evidence from the Gallup World Poll. OECD statistics working papers, 2012(3), 0_1 (2012). https://doi.org/10.1787/5k9b9ltjm937-enBoarini, R., D’Ercole, M.M.: Going beyond GDP: an OECD perspective. Fisc. Stud. 34(3), 289–314 (2013). https://doi.org/10.1111/j.1475-5890.2013.12007.xBradshaw, J., Hoelscher, P., Richardson, D. (eds.): Comparing child well-being in OECD countries: Concepts and methods. Innocenti working paper, IWP-2006-03. UNICEF Innocenti Research Centre, Florence, Italy (2007)Brindley, C.: Barriers to women achieving their entrepreneurial potential. Int. J. Entrep. Behav. Res. Emerald Group Publishing Limited (2005). Retrieved from http://www.emeraldinsight.com/doi/full/10.1108/13552550510590554Burke, A.E., Fitzroy, F.R., Nolan, M.A.: What makes a die-hard entrepreneur? Beyond the “employee or entrepreneur” dichotomy. Small Bus. Econ. 31(2), 93–115 (2008). https://doi.org/10.1007/s11187-007-9086-6Buttner, H.E., Moore, D.P.: Women’s organizational exodus to entrepreneurship: self-reported motivations and correlates with success. J. Small Bus. Manag. 35(1), 34–46 (1997). Retrieved from http://search.ebscohost.comCarter, S.: The rewards of entrepreneurship: exploring the incomes, wealth, and economic wellbeing of entrepreneurial households. Entrep. Theory Pract. 35(1), 39–55 (2011)Castaño, M.-S., Méndez, M.-T., Galindo, M.Á.: The effect of social, cultural, and economic factors on entrepreneurship. J. Bus. Res. 68(7), 1496–1500 (2015). https://doi.org/10.1016/j.jbusres.2015.01.040Castellano, R., Musella, G., Punzo, G.: Structure of the labour market and wage inequality: evidence from European countries. Qual. Quant. 51(5), 2191–2218 (2017)Cervelló-Royo, R., Moya-Clemente, I., Ribes-Giner, G.: Microfinance Institutions (MFIs) in Latin America: Who should finance the entrepreneurial ventures of the less privileged? In: Peris-Ortiz, M., Sahut, J.-M. (eds.) New Challenges in Entrepreneurship and Finance, pp. 235–245. Springer, Cham (2015)Cervelló-Royo, R., Guijarro, F., Martinez-Gomez, V.: Social performance considered within the global performance of Microfinance Institutions: a new approach. Oper. Res. (2017). https://doi.org/10.1007/s12351-017-0360-3Chaaban, J., Irani, A., Khoury, A.: The composite global wellbeing index (CGWBI): a new multi-dimensional measure of human development. Soc. Indic. Res. 129(1), 465–487 (2016). https://doi.org/10.1007/s11205-015-1112-5Chapple, S.: Child wellbeing and sole-parent family structure in the OECD: an analysis. OECD. Social, employment, and migration working papers (82), 0_1 (2009)Christofides, L.N., Polycarpou, A., Vrachimis, K.: Gender wage gaps, “sticky floors” and “glass ceilings” in Europe. Labour Econ. 21, 86–102 (2013). https://doi.org/10.1016/j.labeco.2013.01.003Cumming, D., Hou, W., Lee, E.: Sustainable and ethical entrepreneurship, corporate finance and governance, and institutional reform in China. J. Bus. Ethics 134(4), 505–508 (2016). https://doi.org/10.1007/s10551-014-2381-7Cummins, R.A., Eckersley, R., Pallant, J., Van Vugt, J., Misajon, R.: Developing a national index of subjective wellbeing: the Australian Unity Wellbeing Index. Soc. Indic. Res. 64(2), 159–190 (2003). https://doi.org/10.1023/A:1024704320683De la Cruz Sánchez-Escobedo, M., Díaz-Casero, J.C., Díaz-Aunión, Á.M., Hernández-Mogollón, R.: Gender analysis of entrepreneurial intentions as a function of economic development across three groups of countries. Int. Entrep. Manag. J. 10(4), 747–765 (2014). https://doi.org/10.1007/s11365-014-0314-7Diener, E.: Subjective wellbeing. In: Diener, E. (ed.) The Sicence of Wellbeing, pp. 11–58. Springer, Dordrecht (2009). https://doi.org/10.1007/978-90-481-2350-6_2Dodge, R., Daly, A., Huyton, J., Sanders, L.: The challenge of defining wellbeing. Int. J. Wellbeing 2(3), 222–235 (2012). https://doi.org/10.5502/ijw.v2i3.4Fiss, P.C.: Building better casual theories: a fuzzy set approach to typologies in organization research. Acad. Manag. J. 54(2), 393–420 (2011)Fleche, S., Smith, C., Sorsa, P.: Exploring determinants of subjective wellbeing in OECD countries (2011)Fleche, S., Smith, C., Sorsa, P.: Exploring determinants of subjective wellbeing in OECD countries evidence from the world value survey. Working papers, OECD Statistics (2012). https://doi.org/10.1787/5kg0k6zlcm5k-enFoley, A., Griffith, B.: Education, training and the promotion of high quality entrepreneurs in the Republic of Ireland. In: Scott, M.G., Rosa, P., Klandt, H. (eds.) Educating Entrepreneurs for Wealth Creation. Ashgate, Aldershot (1998)Garikipati, S.: Microcredit and women’s empowerment: through the lens of time-use data from rural India. Dev. Change 43(3), 719–750 (2012). https://doi.org/10.1111/j.1467-7660.2012.01780.xGEM (Global Entrepreneurship Monitor): Global report (2015)Harter, J.K., Schmidt, F.L., Keyes, C.L.M.: Wellbeing in the workplace and its relationship to business outcomes. A review of the Gallup studies. In: Keyes, C.L.M., Haidt, J. (eds.) Flourishing: The Positive Person and the Good Life, pp. 205–224. American Psychologi cal Association, Washington (2003)Henry, C., Foss, L., Ahl, H.: Gender and entrepreneurship research: a review of methodological approaches. Int. Small Bus. J. 34(3), 217–241 (2015). https://doi.org/10.1177/0266242614549779Hessels, J., Van Gelderen, M., Thurik, R.: Entrepreneurial aspirations, motivations, and their drivers”. Small Bus. Econ. 31(3), 323–339 (2008). https://doi.org/10.1007/s11187-008-9134-xIezzi, D.F., Deriu, F.: Women active citizenship and wellbeing: the Italian case. Qual. Quant. 48(2), 845–862 (2014)Jansson, T.: Housing choices and labor income risk. J. Urban Econ. 99, 107–119 (2017). https://doi.org/10.1016/j.jue.2016.12.006Johansen, V., Foss, L.: The effects of entrepreneurship education—does gender matter? Int. J. Entrep. Small Bus. 20(3), 255–271 (2013). https://doi.org/10.1504/IJESB.2013.056889Judge, W.Q., Hu, H.W., Gabrielsson, J., Talaulicar, T., Witt, M.A., Zattoni, A., Kibler, B.: Configurations of capacity for change in entrepreneurial threshold firms: imprinting and strategic choice perspectives. J. Manag. Stud. 52(4), 506–530 (2015). https://doi.org/10.1111/joms.12121Kautonen, T., Kibler, E., Minniti, M.: Late-career entrepreneurship, income and quality of life. J. Bus. Ventur. 32(3), 318–333 (2017). https://doi.org/10.1016/j.jbusvent.2017.02.005Kephart, P., Schumacher, L.: Has the “glass ceiling” cracked? An exploration of women entrepreneurship. J. Leadersh. Organ. Stud. 12(1), 2–15 (2005). https://doi.org/10.1177/107179190501200102Kirkwood, J.: Motivational factors in a push–pull theory of entrepreneurship. Gend. Manag. Int. J. 24(5), 346–364 (2009). https://doi.org/10.1108/17542410910968805Kobeissi, N.: Gender factors and female entrepreneurship: International evidence and policy implications. J. Int. Entrep. 8, 1–35 (2010). Retrieved from https://doi.org/10.1007/s10843-010-0045-yKuckertz, A., Berger, E.S.C., Allmendinger, M.P.: What drives entrepreneurship? A configurational analysis of the determinants of entrepreneurship in innovation-driven economies. Die Betriebswirtschaft/Bus. Adm. Rev. 75(4), 273–288 (2015). https://doi.org/10.1017/cbo9781107415324.004La Placa, V., McNaught, A., Knight, A.: Discourse on wellbeing in research and practice. Int. J. Wellbeing 3, 116–125 (2013). https://doi.org/10.5502/ijw.v3i1.7Langowitz, N., Minniti, M.: The entrepreneurial propensity of women. Entrep. Theory Pract. 31(3), 341–364 (2007). https://doi.org/10.1111/j.1540-6520.2007.00177.xLee, S.S.Y.: Examining policy configurations as conditions for long-term unemployment and non-standard employment in OECD countries using fuzzy-set analysis. Qual. Quant. 47(6), 3521–3536 (2013)Leffler, E., Svedberg, G.: Enterprise learning: a challenge to education? Eur. Educ. Res. J. 4(3), 219–227 (2005)Levie, J., Autio, E.: A theoretical grounding and test of the GEM model. Small Bus. Econ. 31(3), 235–263 (2008). https://doi.org/10.1007/s11187-008-9136-8Maccagnan, A., Wren-Lewis, S., Brown, H., Taylor, T.: Wellbeing and society: towards quantification of the co-benefits of wellbeing. Soc. Indic. Res. 1–27 (2018)Mandl, C., Berger, E.S.C., Kuckertz, A.: Do you plead guilty? Exploring entrepreneurs’ sensemaking-behavior link after business failure. J. Bus. Ventur. Insights 5, 9–13 (2016). https://doi.org/10.1016/j.jbvi.2015.12.002Martin, B.C., McNally, J.J., Kay, M.J.: Examining the formation of human capital in entrepreneurship: a meta-analysis of entrepreneurship education outcomes. J. Bus. Ventur. 28(2), 211–224 (2013). https://doi.org/10.1016/j.jbusvent.2012.03.002McClelland, E., Swail, J., Bell, J., Ibbotson, P.: Following the pathway of female entrepreneurs. Int. J. Entrep. Behav. Res. 11(2), 84–107 (2005). https://doi.org/10.1108/13552550510590527Millán, J.M., Hessels, J., Thurik, R., Aguado, R.: Determinants of job satisfaction: a European comparison of self-employed and paid employees. Small Bus. Econ. 40(3), 651–670 (2013). https://doi.org/10.1007/s11187-011-9380-1Minniti, M., Nardone, C.: Being in someone else’s shoes: the role of gender in nascent entrepreneurship. Small Bus. Econ. 28(2–3), 223–238 (2007). https://doi.org/10.1007/s11187-006-9017-yMishra, V., Nielsen, I., Smyth, R.: How does relative income and variations in short-run wellbeing affect wellbeing in the long run? Empirical evidence from China’s Korean minority. Soc. Indic. Res. 115(1), 67–91 (2014)Murias, P., Martinez, F., de Miguel, C.: An economic wellbeing index for the Spanish provinces: a data envelopment analysis approach. Soc. Indic. Res. 77(3), 395–417 (2006). https://doi.org/10.1007/s11205-005-2613-4Naudé, W., Amorós, J.E., Cisti, O.: Surfeiting, the appetite may sticken: entrepreneurship and happiness. Small Bus. Econ. 42(3), 523–540 (2014)Ng, T.W.H., Feldman, D.C.: Re-examining the relationship between age and voluntary turnover. J. Vocat. Behav. 74(3), 283–294 (2009). https://doi.org/10.1016/j.jvb.2009.01.004O’Connor, A.: A conceptual framework for entrepreneurship education policy: meeting government and economic purposes. J. Bus. Ventur. 28(4), 546–563 (2013). https://doi.org/10.1016/j.jbusvent.2012.07.003Organisation for Economic Co-operation and Development (OECD): OECD guidelines on measuring subjective well-being (2013)Organization for Economic Cooperation and Development: How’s Life? Measuring Wellbeing (2015). http://www.oecdbetterlifeindex.org . Accessed 28 May 2017Orlova, L.V., Sakhabieva, G.A., Vasyaycheva, V.A., Pronina, N.N.: Impact of educational attainment on the development of female entrepreneurship in Kazakhstan. Indian J. Sci. Technol. (2016). https://doi.org/10.17485/ijst/2016/v9i11/89427Osberg, L., Sharpe, A.: An index of economic wellbeing for selected OECD countries. Rev. Income Wealth 5(3), 291–316 (2002). https://doi.org/10.1111/1475-4991.00056Osberg, L., Sharpe, A.: New Estimates of the Index of Economic Wellbeing for Selected OECD Countries, 1980–2007. Centre for the Study of Living Standards, Ottawa (2009)Parasuraman, S., Purohit, Y.S., Godshalk, V.M., Beutell, N.J.: Work and family variables, entrepreneurial career success, and psychological wellbeing. J. Vocat. Behav. 48(3), 275–300 (1996). https://doi.org/10.1006/jvbe.1996.0025Parasuraman, S., & Simmers, C.A.: Type of employment, work–family conflict and well-being: a comparative study. J. Organ. Behav.: Int. J Ind., Occup. Organ. Psychol. Behav. 22(5), 551–568 (2001)Patrick, C., Stephens, H., Weinstein, A.: Where are all the self-employed women? Push and pull factors influencing female labor market decisions. Small Bus. Econ. 46(3), 365–390 (2016). https://doi.org/10.1007/s11187-015-9697-2Poggesi, S., Mari, M., De Vita, L.: What’s new in female entrepreneurship research? Answers from the literature. Int. Entrep. Manag. J. 12(3), 735–764 (2015). https://doi.org/10.1007/s11365-015-0364-5Ragin, C.: The Comparative Method: Moving Beyond Qualitative and Quantitative Strategies. University of California Press, Berkeley (1987)Ragin, C.C.: New directions in comparative research. In: Kohn, M.L. (ed.) Cross-National Research in Sociology, pp. 57–76. Sage, Newbury Park (1989)Ragin, C.C.: Fuzzy-Set Social Science. University of Chicago Press, Chicago (2000)Ragin, Charles C., Sonnett, J.: Between complexity and parsimony: limited diversity, counterfactual cases, and comparative analysis. In: Ragin, Charles C. (ed.) Redesigning Social Inquiry. University of Chicago Press, Chicago (2004)Ragin, C.C.: Redesigning Social Inquiry: Fuzzy Sets and Beyond, vol. 240. University of Chicago Pres, Chicago (2008)Rahman, S.A., Amran, A., Ahmad, N.H., Taghizadeh, S.K.: Enhancing the wellbeing of base of the pyramid entrepreneurs through business success: the role of private organizations. Soc. Indic. Res. 127(1), 195–216 (2016). https://doi.org/10.1007/s11205-015-0951-4Renee Baptiste, N.: Tightening the link between employee wellbeing at work and performance. Manag. Decis. 46(2), 284–309 (2008). https://doi.org/10.1108/00251740810854168Rey-Martí, A., Tur Porcar, A., Mas-Tur, A.: Linking female entrepreneurs’ motivation to business survival. J. Bus. Res. 68(4), 810–814 (2015). https://doi.org/10.1016/j.jbusres.2014.11.033Reynolds, P.D., Bygrave, W.D., Autio, E., Cox, L.W., Hay, M.: Global entrepreneurship monitor, 2002 executive report. London (2002)Ribes-Giner, G., Moya-Clemente, I., Cervelló-Royo, R., Perello-Marin, M.R.: Domestic economic and social conditions empowering female entrepreneurship. J. Bus. Res. 89, 182–189 (2018)Ruth Eikhof, D., Summers, J., Carter, S., Eikhof, D.R., Summers, J., Carter, S.: Women doing their own thing: media representations of female entrepreneurship. Int. J. Entrep. Behav. Res. 19(5), 547–564 (2013). https://doi.org/10.1108/IJEBR-09-2011-0107Sampedro Gallego, R., Camarero Rioja, L.: Female entrepreneurs in rural Spain—the failed subject of development. Rev. Int. Sociol. 65(48), 121–146 (2007)Saridakis, G., Marlow, S., Storey, D.J.: Do different factors explain male and female self-employment rates? J. Bus. Ventur. 29(3), 345–362 (2014). https://doi.org/10.1016/j.jbusvent.2013.04.004Shepherd, D.A., Douglas, E.J., Shanley, M.: New venture survival: ignorance, external shocks, and risk reduction strategies. J. Bus. Ventur. 15(5), 393–410 (2000). https://doi.org/10.1016/S0883-9026(98)00008-1Shepherd, D., Haynie, J.M.: Birds of a feather don’t always flock together: identity management in entrepreneurship. J. Bus. Ventur. 24(4), 316–337 (2009). https://doi.org/10.1016/j.jbusvent.2007.10.005Shinnar, R.S., Hsu, D.K., Powell, B.C.: Self-efficacy, entrepreneurial intentions, and gender: assessing the impact of entrepreneurship education longitudinally. Int. J. Manag. Educ. 12(3), 561–570 (2014). https://doi.org/10.1016/j.ijme.2014.09.005Shir, N.: Entrepreneurial Wellbeing: The Payoff Structure of Business Creation. Stockholm School of Economics, Stockholm (2015)Thiem, A., Dusa, A.: QCA: a package for qualitative comparative analysis. R package version 2.0. R J. 5, 87–97 (2013). Retrieved from https://cran.r-project.org/web/packages/QCA/index.htmlTorri, M.M.C., Martinez, A.: Women’s empowerment and micro-entrepreneurship in India: constructing a new development paradigm? Prog. Dev. Stud. 14(1), 31–48 (2014). https://doi.org/10.1177/1464993413504347Tur-Porcar, A., Mas-Tur, A., Belso, J.A.: Barriers to women entrepreneurship. Different methods, different results? Qual. Quant. 51(5), 2019–2034 (2017)Uy, M.A., Foo, M.Der, Song, Z.: Joint effects of prior start-up experience and coping strategies on entrepreneurs’ psychological wellbeing. J. Bus. Ventur. 28(5), 583–597 (2013). https://doi.org/10.1016/j.jbusvent.2012.04.003Uy, M.A., Sun, S., Foo, M.Der: Affect spin, entrepreneurs’ wellbeing, and venture goal progress: the moderating role of goal orientation. J. Bus. Ventur. 32(4), 443–460 (2017). https://doi.org/10.1016/j.jbusvent.2016.12.001Van der Sluis, J., Van Praag, M., Vijverberg, W.: Education and entrepreneurship selection and performance: a review of empirical literature. J. Econ. Surv. 22(5), 795–841 (2008)Verheul, I., Stel, A.Van, Thurik, R.: Explaining female and male entrepreneurship at the country level. Entrep. Reg. Dev. 18(2), 151–183 (2006). https://doi.org/10.1080/08985620500532053Witbooi, M., Ukpere, W.: Indigenous female entrepreneurship: analytical study on access to finance for women entrepreneurs in South Africa. Afr. J. Bus. Manag. 5(14), 5646–5657 (2011)Woodside, A.G., Bernal, P.M., Coduras, A.: The general theory of culture, entrepreneurship, innovation, and quality-of-life: comparing nurturing versus thwarting enterprise start-ups in BRIC, Denmark, Germany, and the United States. Ind. Mark. Manag. (2015). https://doi.org/10.1016/j.indmarman.2015.11.00