Efficacy of sodium feredetate versus ferrous sulfate in iron deficiency anemia in preganant women

Background: The main aim of the study was to determine the efficacy of Sodium Feredetate with Ferrous Sulfate in treatment of iron deficiency anemia in pregnant women. Rise in hemoglobin after one and two months of treatment with respective drugs and their side effects.Methods: Prospective randomized study carried out between Jan 2008-July 2009 at Government Tertiary Care Level Hospital OBG Department in Mangalore on 74 pregnant women with anemia.Results: Sodium feredetate (Na Fe EDTA) in iron deficiency anemia led to a significant and rapid rise in hemoglobin levels than that with ferrous sulfate in our study.Conclusions: Sodium Feredetate in iron deficiency anemia led to a significant and rapid rise in hemoglobin levels than that with Ferrous Sulfate and also associated with minimal or no side effects

Proportion of pregnancy associated asymptomatic bacteriuria in a tertiary care hospital

Background: Urinary tract infections are a common occurrence in pregnancy. The physiological and anatomical changes associated with pregnancy predispose to UTIs. Main aim of the study is to determine the prevalence of asymptomatic bacteriuria in pregnant women, to identify the commonest microorganisms and antibacterial susceptibility of the isolated organism and to study the adverse maternal and fetal outcome.Methods: Prospective cross sectional study, conducted between July 2016 to July 2017 in a tertiary hospital. All pregnant women without the symptoms of UTI attending prenatal checkups were included, they were evaluated with urine microscopy and culture sensitivity.Results: Out of 250 pregnant women, 24 urine samples were contaminated and were excluded from the study.165 pregnant women had sterile culture. 10 women had insignificant bacteruria. 30 women had significant growth on culture. 2 of the culture positive women and 21 culture negative women lost for follows. So total number of culture positive women were 28 so incidence of asymptomatic bacteruria is 13.7%.Conclusions: Routine urine culture sensitivity even in asymptomatic women should be offered during antenatal visits so that adverse maternal and fetal outcomes can be prevented

Tablet misoprostol as a cervical priming agent prior to surgical abortion

Background: Every effort to promote effective contraceptive methods as well as emergency contraception is being made, still there would be a need and place for termination of pregnancy. Objective of present study was to evaluate and to know the efficacy and adverse effects of tablet misoprostol 400 micro gram as a cervical priming agent administered either by oral or vaginal route, 3 hours before MTP.Methods: Prospective randomized not blinded study carried out for two years at Government Tertiary care level hospital, OBG Department, Mangalore on 100 women with gestational age up to 12 weeks requesting for surgical abortion.Results: In both the groups there was no significant statistical difference with respect to age (p=0.44), parity and gestational age (p=0.59). With respect to baseline cervical dilatation significant statistical difference was not observed in both the groups. Baseline dilatation of the cervix was 8.0 mm versus 8.2 mm (p value=0.55). Baseline cervical dilatation was ≥7mm in 90% of women when tab misoprostol was given by oral route and 94% with vaginal route. There was no significant statistical difference with respect to side effects (p value>0.05) except nausea (p=0.01) found in both the groups. Gastro Intestinal side effects were more in oral misoprostol group, but it was not statistically significant.Conclusions: Oral route is an effective alternative to vaginal route. Oral route is preferred over vaginal route because women can do self-administration at home and there was no internal examination discomfort

Proportion of pregnancy associated asymptomatic bacteriuria in a tertiary care hospital

Background: Urinary tract infections are a common occurrence in pregnancy. The physiological and anatomical changes associated with pregnancy predispose to UTIs. Main aim of the study is to determine the prevalence of asymptomatic bacteriuria in pregnant women, to identify the commonest microorganisms and antibacterial susceptibility of the isolated organism and to study the adverse maternal and fetal outcome.Methods: Prospective cross sectional study, conducted between July 2016 to July 2017 in a tertiary hospital. All pregnant women without the symptoms of UTI attending prenatal checkups were included, they were evaluated with urine microscopy and culture sensitivity.Results: Out of 250 pregnant women, 24 urine samples were contaminated and were excluded from the study.165 pregnant women had sterile culture. 10 women had insignificant bacteruria. 30 women had significant growth on culture. 2 of the culture positive women and 21 culture negative women lost for follows. So total number of culture positive women were 28 so incidence of asymptomatic bacteruria is 13.7%.Conclusions: Routine urine culture sensitivity even in asymptomatic women should be offered during antenatal visits so that adverse maternal and fetal outcomes can be prevented