1,858 research outputs found
Model and Integrate Medical Resource Available Times and Relationships in Verifiably Correct Executable Medical Best Practice Guideline Models (Extended Version)
Improving patient care safety is an ultimate objective for medical
cyber-physical systems. A recent study shows that the patients' death rate is
significantly reduced by computerizing medical best practice guidelines. Recent
data also show that some morbidity and mortality in emergency care are directly
caused by delayed or interrupted treatment due to lack of medical resources.
However, medical guidelines usually do not provide guidance on medical resource
demands and how to manage potential unexpected delays in resource availability.
If medical resources are temporarily unavailable, safety properties in existing
executable medical guideline models may fail which may cause increased risk to
patients under care. The paper presents a separately model and jointly verify
(SMJV) architecture to separately model medical resource available times and
relationships and jointly verify safety properties of existing medical best
practice guideline models with resource models being integrated in. The SMJV
architecture allows medical staff to effectively manage medical resource
demands and unexpected resource availability delays during emergency care. The
separated modeling approach also allows different domain professionals to make
independent model modifications, facilitates the management of frequent
resource availability changes, and enables resource statechart reuse in
multiple medical guideline models. A simplified stroke scenario is used as a
case study to investigate the effectiveness and validity of the SMJV
architecture. The case study indicates that the SMJV architecture is able to
identify unsafe properties caused by unexpected resource delays.Comment: full version, 12 page
MFQE 2.0: A New Approach for Multi-frame Quality Enhancement on Compressed Video
The past few years have witnessed great success in applying deep learning to
enhance the quality of compressed image/video. The existing approaches mainly
focus on enhancing the quality of a single frame, not considering the
similarity between consecutive frames. Since heavy fluctuation exists across
compressed video frames as investigated in this paper, frame similarity can be
utilized for quality enhancement of low-quality frames given their neighboring
high-quality frames. This task is Multi-Frame Quality Enhancement (MFQE).
Accordingly, this paper proposes an MFQE approach for compressed video, as the
first attempt in this direction. In our approach, we firstly develop a
Bidirectional Long Short-Term Memory (BiLSTM) based detector to locate Peak
Quality Frames (PQFs) in compressed video. Then, a novel Multi-Frame
Convolutional Neural Network (MF-CNN) is designed to enhance the quality of
compressed video, in which the non-PQF and its nearest two PQFs are the input.
In MF-CNN, motion between the non-PQF and PQFs is compensated by a motion
compensation subnet. Subsequently, a quality enhancement subnet fuses the
non-PQF and compensated PQFs, and then reduces the compression artifacts of the
non-PQF. Also, PQF quality is enhanced in the same way. Finally, experiments
validate the effectiveness and generalization ability of our MFQE approach in
advancing the state-of-the-art quality enhancement of compressed video. The
code is available at https://github.com/RyanXingQL/MFQEv2.0.git.Comment: Accepted to TPAMI in September, 2019. v6 updates: correct units in
Fig. 11; correct author info; delete bio photos. arXiv admin note: text
overlap with arXiv:1803.0468
Vortex images on Ba{1-x}KxFe2As2 observed directly by the magnetic force microscopy
The vortex states on optimally doped Ba0.6K0.4Fe2As2 and underdoped
Ba0.77K0.23Fe2As2 single crystals are imaged by magnetic force microscopy at
various magnetic fields below 100 Oe. Local triangular vortex clusters are
observed in optimally doped samples. The vortices are more ordered than those
in Ba(Fe{1-x}Co{x})2As2, and the calculated pinning force per unit length is
about 1 order of magnitude weaker than that in optimally Co-doped 122 at the
same magnetic field, indicating that the Co doping at the Fe sites induces
stronger pinning. The proportion of six-neighbored vortices to the total amount
increases quickly with increasing magnetic field, and the estimated value
reaches 100% at several tesla. Vortex chains are also found in some local
regions, which enhance the pinning force as well as the critical current
density. Lines of vortex chains are observed in underdoped samples, and they
may have originated from the strong pinning near the twin boundaries arising
from the structural transition.Comment: 7 pages, 8 figure
Human Cancer and Platelet Interaction, a Potential Therapeutic Target
Cancer patients experience a four-fold increase in thrombosis risk, indicating that cancer development and progression are associated with platelet activation. Xenograft experiments and transgenic mouse models further demonstrate that platelet activation and platelet-cancer cell interaction are crucial for cancer metastasis. Direct or indirect interaction of platelets induces cancer cell plasticity and enhances survival and extravasation of circulating cancer cells during dissemination. In vivo and in vitro experiments also demonstrate that cancer cells induce platelet aggregation, suggesting that platelet-cancer interaction is bidirectional. Therefore, understanding how platelets crosstalk with cancer cells may identify potential strategies to inhibit cancer metastasis and to reduce cancer-related thrombosis. Here, we discuss the potential function of platelets in regulating cancer progression and summarize the factors and signaling pathways that mediate the cancer cell-platelet interaction
Quantum Anomalous Hall Effect in Graphene Proximity Coupled to an Antiferromagnetic Insulator
We propose realizing the quantum anomalous Hall effect by proximity coupling
graphene to an antiferromagnetic insulator that provides both broken
time-reversal symmetry and spin-orbit coupling. We illustrate our idea by
performing ab initio calculations for graphene adsorbed on the (111) surface of
BiFeO3. In this case, we find that the proximity-induced exchange field in
graphene is about 70 meV, and that a topologically nontrivial band gap is
opened by Rashba spin-orbit coupling. The size of the gap depends on the
separation between the graphene and the thin film substrate, which can be tuned
experimentally by applying external pressure.Comment: 5pages, 5 figure
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