8,540 research outputs found

    Single-shot determination of spin-polarization for ultrarelativistic electron beams via nonlinear Compton scattering

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    Impacts of spin-polarization of an ultrarelativistic electron beam head-on colliding with a strong laser pulse on emitted photon spectra and electron dynamics have been investigated in the quantum radiation regime. We simulate photon emissions quantum mechanically and electron dynamics semiclassically via taking spin-resolved radiation probabilities in the local constant field approximation. A small ellipticity of the laser field brings about an asymmetry in angle-resolved photon spectrum, which sensitively relies on the polarization of the electron beam. The asymmetry is particularly significant in high-energy photon spectra, and is employed for the polarization detection of a high-energy electron beam with extraordinary precision, e.g., better than 0.3\% for a few-GeV electron beam at a density of the scale of 101610^{16} cm−3^{-3} with currently available strong laser fields. This method demonstrates for the first time a way of single-shot determination of polarization for ultrarelativistic electron beams via nonlinear Compton scattering. A similar method based on the asymmetry in the electron momentum distribution after the interaction due to spin-dependent radiation reaction is proposed as well

    Inhibition of foot-and-mouth disease virus replication in vitro and in vivo by small interfering RNA

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    By using bioinformatics computer programs, all foot-and-mouth disease virus (FMDV) genome sequences in public-domain databases were analyzed. Based on the results of homology analysis, 2 specific small interfering RNA (siRNA) targeting homogenous 3D and 2B1 regions of 7 serotypes of FMDV were prepared and 2 siRNA-expression vectors, pSi-FMD2 and pSi-FMD3, were constructed. The siRNA-expressing vectors were used to test the ability of siRNAs to inhibit virus replication in baby hamster kidney (BHK-21) cells and suckling mice, a commonly used small animal model. The results demonstrated that transfection of BHK-21 cells with siRNA-expressing plasmids significantly weakened the cytopathic effect (CPE). Moreover, BHK-21 cells transiently transfected with short hairpin RNA (shRNA)-expressing plasmids were specifically resistant to the infection of the FMDV serotypes A, O, and Asia I and this the antiviral effects persisted for almost 48 hours. We measured the viral titers, the 50% tissue culture infective dose (TCID50) in cells transfected with anti-FMDV siRNAs was found to be lower than that of the control cells. Furthermore, subcutaneous injection of siRNA-expressing plasmids in the neck of the suckling mice made them less susceptible to infection with O, and Asia I serotypes of FMDV

    Expression of telomerase inhibits hydroxyl radical-induced apoptosis in normal telomerase negative human lung fibroblasts

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    AbstractIn tumor cells telomerase activity is associated with resistance to apoptosis and the introduction of the human telomerase reverse transcriptase (hTERT) subunit into normal human cells is associated with life span extension of the cells. To determine the role of telomerase in regulating apoptosis, telomerase negative human embryo lung fibroblasts were transfected with the hTERT gene. Unlike the control fibroblasts, the telomerase-expressing cells had elongated telomeres and were resistant to apoptosis induced by hydroxyl radicals. The results indicate that expression of telomerase and, thus, the maintenance of telomere length in normal human somatic cells caused resistance to not only cellular senescence but also apoptosis. Moreover, we found that hydroxyl radical-induced apoptosis in telomerase-expressing and control fibroblasts was caspase-3 independent. These findings have revealed a new type of interrelation between telomerase and caspase-3, which may indicate that in this case the expressed telomerase may inhibit apoptosis at a site not related to the caspase-3 cascade

    Synthesis and Photocatalytic Activity of ZnxCd1–xS/TiO2 Heterostructures Nanofibre Prepared by Combining Electrospinning and Hydrothermal Method

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    The ZnxCd1–xS/TiO2 hierarchical heterostructures were successfully fabricated by combining electrospinning technology and hydrothermal methods. The morphology, crystallinity, composition and band gap of ZnxCd1–xS/TiO2 were characterized by SEM, XRD, EDS, and UV-vis diffuse reflectance spectroscopy. The results indicated the sulphur concentration had a significant influence on the composition and morphology of the products. The values of the band gap energy for ZnxCd1–xS/TiO2 varied from 2.33 to 2.66 eV with the change of sulphur concentration.Whenthe molar ratio of S/Ti was 0.96, the ZnxCd1–xS/TiO2 hierarchical heterostructures exhibited enhanced visible light photocatalytic behaviour for the decomposition of Rhodamine B (RhB) under visible light irradiation. The photocatalytic degradation of RhB followed first-order reaction kinetics.KEYWORDS Electrospinning, heterostructures, photocatalysis, dye degradition

    The width-flux relation of the broad iron line during the state transition of the black hole X-ray binaries

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    The observation of varying broad iron lines during the state transition of the black hole X-ray binaries (BHXBs) have been accumulating.In this work, the relation between the normalized intensity and the width of iron lines is investigated, in order to understand better the variation of iron lines and possibly its connection to state transition. Considering the uncertainties due to ionization and illuminating X-rays, only the effects of geometry and gravity are taken into account. Three scenarios were studied, i.e., the continuous disk model, innermost annulus model, and the cloud model. As shown by our calculations, at given iron width, the line flux of the cloud model is smaller than that of the continuous disk model; while for the innermost annulus model, the width is almost unrelated with the flux. The range of the line strength depends on both the BH spin and the inclination of the disk. We then apply to the observation of MAXI J1631-479 by NuSTAR during its decay from the soft state to the intermediate state. We estimated the relative line strength and width according to the spectral fitting results by Xu et al.(2020), and then compared with our theoretical width-flux relation. It was found that the cloud model was more favored. We further modeled the iron line profiles, and found that the cloud model can explain both the line profile and its variation with reasonable parameters.Comment: 7 figures, 12 pages, accepted for publication in RA
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