103 research outputs found

    A College Campus Crisis: Are Students Getting The Mental Health Support That They Need During the COVID-19 Pandemic?

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    The purpose of this research study is to address the increased need for mental health support among college students during the COVID-19 pandemic (March 2020-May 2021), and to ensure students are getting the full mental health support that they need from their campus counseling center. The study will include residential undergraduate and graduate students from Rowan University who have utilized the university\u27s Counseling and Psychological Services (CPS) office. Mixed methods of quantitative and qualitative data will be used to collect student responses and answer the research questions. The first step will include participation in an online survey that collects student demographic information and asks students to indicate the type of experiences they have had with the CPS office using a five-point likert scale. Following this data analysis and research, students who expressed interest in participating based on self-identification within the survey will be randomly selected to participate in semi-structured interviews where they will be asked to reflect more on their personal experiences with the office and express any impacts they believe COVID-19 may have had on their experience. To analyze the data, I will compare the overall experiences of the students who took part in my quantitative survey to determine whether or not the Counseling and Psychological Services office has shown significant support to students with mental health disorders. I will then use the qualitative information I gathered from my interviews in the randomly selected subgroups to further interpret why students did or did not feel supported by the Counseling and Psychological Services Office, and what support (if any) may have been impacted by the COVID-19 pandemic

    Vice Director Chief Operating Officer Deans of Faculties Dean of Studies Director of External Relations

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    TERMS OF REFERENCE The Council shall have the sole operational and strategic management, governance, control and supervision of the School subject to the regulations of the University of London and those that exist in relation to the operation of an HEI as determined by government and other external agencies. Its specific duties and responsibilities are: 1. To appoint a Chairman and Deputy Chairman. 2. To appoint members of the Council and the Court. 3. To appoint the Honorary Treasurer, who shall be Chairman of the Planning & Finance Committee. 4. To ensure the School carries out all activities safely and with regard to the health and safety of all its students, staff and those who may be affected by its activities. 5. To ensure that the School provides equal opportunities for its staff and students and undertakes all its activities in relation to equal opportunities. 6. To manage the School in relation to the strategic and operational risks and opportunities identified. 7. Strategy and Organisation (i) To review and approve the School Strategy, Mission Statement and Objectives and to monitor performance of the School in relation to these; (ii) to undertake strategic reviews from time to time of specific or all areas of activity; (iii) to approve the Learning, Teaching, and Assessment Strategy on the recommendation of the Senate; (iv) to approve the Research Strategy on the recommendation of the Senate; (v) to approve changes to the academic structure of the School including the organisation of its teaching and research activities, and (vi) to approve the constitution of the Students ’ Representative Council

    Holographic RG Flows and Universal Structures on the Coulomb Branch of N=2 Supersymmetric Large n Gauge Theory

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    We report on our results of D3-brane probing a large class of generalised type IIB supergravity solutions presented very recently in the literature. The structure of the solutions is controlled by a single non-linear differential equation. These solutions correspond to renormalisation group flows from pure N=4 supersymmetric gauge theory to an N=2 gauge theory with a massive adjoint scalar. The gauge group is SU(n) with n large. After presenting the general result, we focus on one of the new solutions, solving for the specific coordinates needed to display the explicit metric on the moduli space. We obtain an appropriately holomorphic result for the coupling. We look for the singular locus, and interestingly, the final result again manifests itself in terms of a square root branch cut on the complex plane, as previously found for a set of solutions for which the details are very different. This, together with the existence of the single simple non-linear differential equation, is further evidence in support of an earlier suggestion that there is a very simple model --perhaps a matrix model with relation to the Calogero-Moser integrable system-- underlying this gauge theory physics.Comment: 14 pages, LaTeX, 1 figur

    グローバリゼーションと中国の対外経済関係論(下‐2・完)

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    まえがき 一 第二次大戦後における二つの対抗するグローパリズムー資本主義対社会主義の対峙 1 リベラリズムの経済理論におけるグローパリズム 2 マルクス主義経済理論におけるグローパリズム 3 両グローパリズムの対峠の狭間におけるナショナリズムの地位 二 社会主義グローパリズムの現実展開過程における相克と社会主義陣営の崩壊 1 東欧における社会主義陣営の崩壊 2 中国のソ連主導型社会主義陣営からの離脱,対立・対抗から新たな国家間関係へ(以上第27巻第3号) 三 中国の社会主義陣営崩壊認識と新たな対外戦略 1 聯美反蘇外交 2 世界的な社会主義革命論の取り下げ,ナショナリズムへの傾斜,反覇権闘争 四 中国にみるマルクス主義グローパリズム,ナショナリズムと国民国家 1 マルクス主義グローパリズムにおける民族問題と国民国家 2 中国におけるマルクス主義グローパリズムと社会主義民族国家論(以上第27巻第4号) 五 現下のグローバリゼーションに対する中国の対外経済認識 1 現下のグローパリゼーションの風潮に対する中国の基本姿勢 2 経済のグローバリゼーションと現下の世界政治経済に対する中国の認識 六 経済のグローパリゼーション下における中国対外貿易と外資利用の定在 1 工業化の発展段階と対外貿易の内的構造からみた貿易戦略と政策指向 2 経済のグローパリゼーション下における要素流動化と国際分業の新展開(以上第28巻第3号) 七 WTO加盟後の貿易戦略政策と外資戦略政策 1 WTO加盟後における貿易戦略政策 2 WTO加盟後における外資直接投資導入戦略(本号

    グローバリゼーションと中国の対外経済関係論(上)

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    まえがき 一 第二次世界大戦後における二つの対抗するグローパリズムー資本主義対社会主義の対時 1 リベラリズムの経済理論におけるグローパリズム 2 マルクス主義経済理論におけるグローパリズム 3 両グローパリズムの対峠の狭間におけるナショナリズムの地位 二 社会主義グローパリズムの現実展開過程における相克と社会主義陣営の崩壊 1 東欧における社会主義陣営の崩壊 2 中国のソ連主導型社会主義陣営からの離脱,対立・抗争から新たな国家間関 係

    Prospects for SIMPLE 2000: A large-mass, low-background Superheated Droplet Detector for WIMP searches

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    SIMPLE 2000 (Superheated Instrument for Massive ParticLE searches) will consist of an array of eight to sixteen large active mass (15\sim15 g) Superheated Droplet Detectors(SDDs) to be installed in the new underground laboratory of Rustrel-Pays d'Apt. Several factors make of SDDs an attractive approach for the detection of Weakly Interacting Massive Particles (WIMPs), namely their intrinsic insensitivity to minimum ionizing particles, high fluorine content, low cost and operation near ambient pressure and temperature. We comment here on the fabrication, calibration and already-competitive first limits from SIMPLE prototype SDDs, as well as on the expected immediate increase in sensitivity of the program, which aims at an exposure of >>25 kg-day during the year 2000. The ability of modest-mass fluorine-rich detectors to explore regions of neutralino parameter space beyond the reach of the most ambitious cryogenic projects is pointed out.Comment: 19 pages, 10 figures included. New Journal of Physics, in pres

    Implications of the Quark Mass Hierarchy on Flavor Mixings

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    We stress that the observed pattern of flavor mixings can be partly interpreted by the quark mass hierarchy without the assumption of specific quark mass matrices. The quantitatively proper relations between the Kobayashi-Maskawa matrix elements and quark mass ratios, such as VcbVts2(msmbmcmt)[1+3(msmb+mcmt)],|V_{cb}| \approx |V_{ts}| \approx \sqrt{2} (\frac{m_s}{m_b} -\frac{m_c}{m_t}) [1 + 3 (\frac{m_s}{m_b} + \frac{m_c}{m_t} ) ], are obtainable from a simple {\it Ansatz} of flavor permutation symmetry breaking at the weak scale. We prescribe the same {\it Ansatz} at the supersymmetric grand unified theory scale, and find that its all low-energy consequences on flavor mixings and CPCP violation are in good agreement with current experimental data.Comment: Latex 19 pages including 5 PS figure

    Integration of multiple data sources to prioritize candidate genes using discounted rating system

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    Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their similarity to known disease genes. Most of existing gene prioritization methods access only one genomic data source, which is noisy and incomplete. Thus, there is a need for the integration of multiple data sources containing different information. Results: In this paper, we proposed a combination strategy, called discounted rating system (DRS). We performed leave one out cross validation to compare it with N-dimensional order statistics (NDOS) used in Endeavour. Results showed that the AUC (Area Under the Curve) values achieved by DRS were comparable with NDOS on most of the disease families. But DRS worked much faster than NDOS, especially when the number of data sources increases. When there are 100 candidate genes and 20 data sources, DRS works more than 180 times faster than NDOS. In the framework of DRS, we give different weights for different data sources. The weighted DRS achieved significantly higher AUC values than NDOS. Conclusion: The proposed DRS algorithm is a powerful and effective framework for candidate gene prioritization. If weights of different data sources are proper given, the DRS algorithm will perform better

    Association of Serum Ustekinumab Levels With Clinical Response in Psoriasis

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    Importance: High-cost biologic therapies have transformed the management of immune-mediated inflammatory diseases. To optimize outcomes and reduce costs, dose adjustment informed by measurement of circulating drug levels has been shown to be effective in various settings. However, limited evidence exists for this approach with the interleukin 12 and interleukin 23 inhibitor ustekinumab. Objective: To evaluate clinical utility of therapeutic drug monitoring for ustekinumab in patients with psoriasis. Design, Setting, and Participants: A prospective observational cohort of 491 adults with psoriasis was recruited to the multicenter Biomarkers of Systemic Treatment Outcomes in Psoriasis study within the British Association of Dermatologists Biologic and Immunomodulators Register from June 2009 to December 2017; samples from some patients were taken between 2009 and 2011 as part of a pilot study with the same inclusion criteria. Exposure: Serum ustekinumab level measured at any point during the dosing cycle using an enzyme-linked immunosorbent assay. Main Outcomes and Measures@ Disease activity measured using the Psoriasis Area and Severity Index (PASI) score. Treatment response outcomes were PASI75 (75% reduction in PASI score from baseline [primary outcome]), PASI90 (90% reduction of PASI score from baseline), and absolute PASI score of 1.5 or less. Results: A total of 491 patients (171 women and 320 men; mean [SD] age, 45.7 [12.8] years) had 1 or more serum samples (total, 853 samples obtained 0-56 weeks from start of treatment) and 1 or more PASI scores within the first year of treatment. Antidrug antibodies were detected in only 17 of 490 patients (3.5%). Early measured drug levels (1-12 weeks after starting treatment) were associated with PASI75 response 6 months after starting treatment (odds ratio, 1.38; 95% CI, 1.11-1.71) when adjusted for baseline PASI score, age, and ustekinumab dose. However, this finding was not consistent across the other PASI outcomes (PASI90 and PASI score of ≤1.5). Conclusions and Relevance: This real-world study provides evidence that measurement of early serum ustekinumab levels could be useful to direct the treatment strategy for psoriasis. Adequate drug exposure early in the treatment cycle may be particularly important in determining clinical outcome

    Alcohol abuse associated with poor response to systemic therapies for psoriasis: findings from a prospective multicentre cohort study

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    Background Factors that might influence response to systemic treatment for moderate-to-severe psoriasis are varied, and generally, are poorly understood, aside from high body weight, suggesting that other unidentified factors may be relevant in determining response to treatment. The impact of alcohol abuse on treatment response has not been previously investigated. Objective To investigate whether alcohol abuse is associated with poor response to treatment for psoriasis. Methods Prospective cohort study in which response to systemic therapies was assessed using the Psoriasis Area and Severity Index (PASI). The CAGE questionnaire was used to screen for alcohol abuse. A multivariable factional polynomial linear regression model was used to examine factors associated with change in PASI between baseline and follow-up. Results The cohort comprised of 266 patients (biologic cohort, n=134; conventional systemic cohort, n=132). For the entire cohort, the median (interquartile range) PASI improved from 13[10-18.3] at baseline to 3[1-7.5] during follow-up. A higher CAGE score (regression co-efficient: 1.40; 95% CIs: 0.04-2.77); obesity (1.84; 0.48-3.20); and receiving a conventional systemic rather than a biologic therapy (4.39; 2.84-5.95) were significantly associated with poor response to treatment; whereas a higher baseline PASI (-0.83; -0.92,-0.74) was associated with better response to treatment. Conclusion The poor response to therapy associated with alcohol abuse and obesity found in people with psoriasis calls for lifestyle behaviour change interventions and support as part of routine clinical care. Targeting interventions to prevent, detect and manage alcohol abuse among people with psoriasis is needed to minimise adverse health consequences and improve treatment response
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