Review of the Netherlands’ contribution to the humanitarian response to the Syria Crisis: 2011-2014

This report examines the Netherlands contribution to the humanitarian response to the Syrian crisis and the impact on neighbouring countries in the period 15 March 2011 to 31 December 2014. Data and other types of information used for the analysis are actual until 31 December

Evolution of costs of inflammatory bowel disease over two years of follow-up

Background: With the increasing use of anti-TNF therapy in inflammatory bowel disease (IBD), a shift of costs has been observed with medication costs replacing hospitalization and surgery as major cost driver. We aimed to explore the evolution of IBD-related costs over two years of follow-up. Methods and Findings: In total 1,307 Crohn's disease (CD) patients and 915 ulcerative colitis (UC) patients were prospectively followed for two years by three-monthly web-based questionnaires. Changes of healthcare costs, productivity costs and out-of-pocket costs over time were assessed using mixed model analysis. Multivariable logistic regression analysis was used to identify costs drivers. In total 737 CD patients and 566 UC were included. Total costs were stable over two years of follow-up, with annual total costs of € 7,835 in CD and € 3,600 in UC. However, within healthcare costs, the proportion of anti-TNF therapy-related costs increased from 64% to 72% in CD (p<0.01) and from 31% to 39% in UC (p < 0.01). In contrast, the proportion of hospitalization costs decreased from 19% to 13% in CD (p<0.01), and 22% to 15% in UC (p < 0.01). Penetrating disease course predicted an increase of healthcare costs (adjusted odds ratio (adj. OR) 1.95 (95% CI 1.02-3.37) in CD and age <40 years in UC (adj. OR 4.72 (95% CI 1.61-13.86)). Conclusions: BD-related costs remained stable over two years. However, the proportion of anti-TNFrelated healthcare costs increased, while hospitalization costs decreased. Factors associated with increased costs were penetrating disease course in CD and age <40 in UC

Political Corruption in Eastern Europe: Politics after Communism by Tatiana Kostadinova

More than 20 years ago, when Eastern European countries embarked on their corruption-prone transitions from communism, Robert Klitgaard (Adjusting to Reality: Beyond “State versus Market” in Economic Development, 1991), once designated the “world's leading expert on corruption” (in The Christian Science Monitor, March 2, 1994), proposed the abandonment of the search for the “many, many causes and conditions” of corruption. In despair at what he saw as academic hair splitting in the burgeoning study of corruption, he claimed to be more “pragmatic” by focusing instead on ways by which policy and management could reduce corruption. In hindsight, Klitgaard's intellectual impatience appears ironic as the debate on the causes of corruption was only about to commence, resulting in an expanding list of suggested causes—often derived from Eastern European experiences.</jats:p