138 research outputs found
Glycation associated skin autofluorescence and skin elasticity are related to chronological age and body mass index of healthy subjects
Experimental Investigation Into the Deep Penetration of Soft Solids by Sharp and Blunt Punches, With Application to the Piercing of Skin
An experimental study has been conducted on the penetration of silicone rubbers and human skin in vivo by sharp-tipped and flat-bottomed cylindrical punches. A penetrometer was developed to measure the penetration of human skin in vivo, whilst a conventional screw-driven testing machine was used to penetrate the silicone rubbers. The experiments reveal that the penetration mechanism of a soft solid depends upon the punch tip geometry: a sharp tipped punch penetrates by the formation and wedging open of a mode I planar crack, whilst a flat-bottomed punch penetrates by the growth of a mode II ring crack. The planar crack advances with the punch, and friction along the flanks of the punch leads to a rising load versus displacement response. In contrast, the flat-bottomed punch penetrates by jerky crack advance and the load on the punch is unsteady. The average penetration pressure on the shank cross-section of a flat-bottomed punch exceeds that for a sharp-tipped punch of the same diameter. In addition, the penetration pressure decreases as the diameter of the sharp-tipped punch increases. These findings are in broad agreement with the predictions of Shergold and Fleck (Proceedings of the Royal Society, London, Series A, 2004), who proposed models for the penetration of a soft solid by a sharp-tipped and flat-bottomed punch
Constitutive modelling of skin ageing
The objective of this chapter is to review the main biomechanical and structural aspects associated with both intrinsic and extrinsic skin ageing, and to present potential research avenues to account for these effects in mathematical and computational models of the skin. This will be illustrated through recent work of the authors which provides a basis to those interested in developing mechanistic constitutive models capturing the mechanobiology of skin across the life course
Adaptation of a Cruciform Testing Machine Zwick/Roell Z050 for Biaxial Compression Creep Experiments
Two-dimensional stress-relaxation behavior of human skin as influenced by non-enzymatic glycation and the inhibitory agent aminoguanidine
Two-dimensional stress-relaxation behavior of human skin as influenced by non-enzymatic glycation and the inhibitory agent aminoguanidine
Histologischer Aufbau und mechanische Eigenschaften der Membrana interossea antebrachii
Neue epidural arbeitende Gehirndrucksonde — Labortests und Tierversuche — Stand der Entwicklung
- …
