CITY:mobil. Handlungsfolgenabschaetzung - Spielraeume und Planungshilfen fuer stadtvertraegliche Mobilitaet. Materialband. Hauptprojektteil HP 4. T. 1 Ausfuehrliche Beschreibung von sechs ausgewaehlten Instrumenten und Massnahmen

SIGLEAvailable from TIB Hannover: RR 9139(3,mat)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman

CITY:mobil. Handlungsfolgenabschaetzung - Spielraeume und Planungshilfen fuer stadtvertraegliche Mobilitaet: Schlussbericht. Hauptprojektphase HP 4. T. 1

SIGLEAvailable from TIB Hannover: RR 9139(3,Schl.)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman

CITY:mobil. Massnahmenkatalog fuer Kommunen Ergebnisse eines diskursiven Beschreibungsverfahrens. Schlussbericht Hauptprojektphase HP 4. T. 2

Available from TIB Hannover: RR 9139(4)+a / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Bildung, Wissenschaft, Forschung und Technologie, Bonn (Germany)DEGerman

Gesamtoekologische Betrachtung der Herstellung und Anwendung chemischer Produkte - Bausteine fuer ein strategisches Stoffstrommanagement Anlagenband zum Endbericht

The targetted influencing and control of anthropogenic materials flows within the context of a prevention-oriented environmental policy and of a sustainable form of development is characterized by a high degree of complexity and interlinkage. Accordingly, the conception of ecological materials flow management as yet suffers under a lack of methodological maturity. For the performance of this study, a novel methodological approach was developed, and tested on a group of intermediate chemical products (chloronitrobenzenes), a group of final products (polyurethanes), and with case examples (azo dyes on chloronitrobenzene basis for textile dyeing; rigid expanded polyurethane sheets for thermal insulation in buildings). The essential elements of this method are: the bundling of several products or product life cycles by means of the new category of product trees, the historical analysis of the development and differentiation of product trees, the multidisciplinary examination of the framework conditions and influencing factors that are currently of relevance to chemical production and to the application of chemical products (including, inter alia, technical materials management, economic and social aspects, and the regulatory framework of environmental and public health policy), and the development of criteria for strategies aimed at a comprehensive ecological structuring of the production and application of chemical products. The approach links information on the requirements for action in environmental and public health policy with information on the actual room for manoeuvre of actors, and can thus be of use for both product-related assessment issues, entrepreneurial or supra-sectoral materials flow management, and in the further development of framework conditions of environmental policy. (orig.)Available from TIB Hannover: RN 8908(94-091,2) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit, Bonn (Germany)DEGerman

Gesamtoekologische Betrachtung der Herstellung und Anwendung chemischer Produkte - Bausteine fuer ein strategisches Stoffstrommanagement Endbericht

The targetted influencing and control of anthropogenic materials flows within the context of a prevention-oriented environmental policy and of a sustainable form of development is characterized by a high degree of complexity and interlinkage. Accordingly, the conception of ecological materials flow management as yet suffers under a lack of methodological maturity. For the performance of this study, a novel methodological approach was developed, and tested on a group of intermediate chemical products (chloronitrobenzenes), a group of final products (polyurethanes), and with case examples (azo dyes on chloronitrobenzene basis for textile dyeing; rigid expanded polyurethane sheets for thermal insulation in buildings). The essential elements of this method are: the bundling of several products or product life cycles by means of the new category of product trees, the historical analysis of the development and differentiation of product trees, the multidisciplinary examination of the framework conditions and influencing factors that are currently of relevance to chemical production and to the application of chemical products (including, inter alia, technical, materials management, economic and social aspects, and the regulatory framework of environmental and public health policy), and the development of criteria for strategies aimed at a comprehensive ecological structuring of the production and application of chemical products. The approach links information on the requirements for action in environmental and public health policy with information on the actual room for manoeuvre of actors, and can thus be of use for both product-related assessment issues, entrepreneurial or supra-sectoral materials flow management, and in the further development of framework conditions of environmental policy. (orig.)Available from TIB Hannover: RN 8908(94-091,1) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEBundesministerium fuer Umwelt, Naturschutz und Reaktorsicherheit, Bonn (Germany)DEGerman

Lutetium-177-PSMA radioligand therapy. Consensus within the framework of GKV-funded care between the university hospitals in Aachen, Bonn, Dusseldorf, Essen, and Cologne and the MDK Nordrhein

In the last 3 years, Lutetium-177 prostate-specific membrane antigen radioligand therapy (Lu-177-PSMA-RLT) has received increasing attention in nuclear medicine as a new form of treatment for castration-resistant metastatic prostate cancer. This therapy combines the radionuclide Lutetium-177, which has been therapeutically used in nuclear medicine for many years, with a molecular target of the transmembrane prostate-specific membrane antigen expressed by prostate cancer cells. Since there are no prospective randomized studies on Lu-177-PSMA-RLT and the question of reimbursement has repeatedly been the subject of review by the MDK Nordrhein (Medischenische Dienst der Krankenversicherung), there was a desire because of the increasing number of patients being treated to clarify under which circumstances Lu-177-PSMA-RLT can be reimbursed by German statutory health insurance. The goals of this article are to help treating physicians understand how this new therapy option works, to integrate it in the overall therapy concept for castration-resistant metastatic prostate cancer, and, above all, to use Lu-177-PSMA-RLT-based on the current data-at the right place in the therapy sequence of castration-resistant metastatic prostate cancer