Teaching Indigenous children : listening to and learning from indigenous teachers

This article is based on the findings of a qualitative case study that examined the professional experiences and career pathways of fifty current and former Australian Indigenous teachers. Here, we draw on data obtained from semi-structured interviews with the teachers to highlight their knowledge in three key areas: ‘Indigenous ways of knowing’, ‘Indigenous learners’ lives beyond the classroom’ and ‘Building relationships with Indigenous students and communities’. We suggest that Indigenous teachers can potentially play important roles as teacher educators and as mentors to non-Indigenous teachers and preservice teachers. We argue that it is important for schooling systems and teacher education to create and formalise opportunities for non-Indigenous teachers and preservice teachers to listen to, and learn from their Indigenous colleagues

Knowledge Creation Processes in Foundation Degree Partnership Working

This thesis seeks to develop an understanding of knowledge creation processes in partnership working, conditions which foster these, and their impact on longer-term sustainability. The partnership, between a university in Greater Manchester and the Strategic Health Authority, was established in 2002 to train a new role of healthcare worker through the delivery a foundation degree in health and social care. At that time foundation degrees were new, and the 'Assistant Practitioner' role was being introduced to bridge the gap between staff at registered professional level and those at support worker level. The role is intended as generic and patient-centred in crossing traditional professional boundaries, and so presents challenges in creating, sharing and embedding knowledge, which accords well with the concept of knowledge management. The study explores Nonaka and Takeuchi's (1995) model of Knowledge Management, and Engestrom's (1997,2001) Activity Theory, in relation to how these constructs may provide insight into the knowledge processes in partnership working. 'Partnership' is a contested concept which is debated in the context of the policy drivers underpinning the development. The enquiry has employed a case study approach within an interpretive paradigm with data gathered through semi-structured interviews and a focus group. Thematic analysis of the interview data identifies and explores themes in knowledge creation and partnership working which raise questions of power dynamics. These questions are not fully addressed by the knowledge creation models, and so the relationship between power, knowledge and discourse is further considered through a Foucauldian discourse analysis approach to the focus group. The conclusions support the value of the knowledge creation models for developing insights into how partnership working supports innovation and may sustain it. The discourse analysis reveals the pervasiveness of power relationships, reflects on their impact on knowledge creation, and considers the consequences for longer-term sustainability of the partnership

Privacy and the Health Industry

This article examines confidentiality and freedom of information in the health industry and access to medical records in both the public and private sector. In particular, it considers changes to the access of medical records in the private health sector after the amendments to the Privacy Act 1988 (Cth) in 2003

Raf-1 kinase inhibitor protein modulation of the cellular response to chemotherapeutic drugs and PDE5 inhibitors

RKIP was initially discovered as an endogenous inhibitor of the ERK and NF-κB pathways,and was also shown to prolong the activation of GPCRs via inhibition of the GRK2 protein. Now increasing evidence has linked RKIP to a metastases suppressing and chemo-sensitising role in cancer cells.The chemo-sensitising effect of RKIP was investigated in a colon carcinoma cell line using a variety of chemotherapeutic agents from conventional agents to newer targeted therapies. Initial results suggested that role of RKIP in the modulation of chemotherapeutic drug response was at the level of apoptosis; there did not appear to be great observable effects in the cell proliferative response and the cell cycle distribution of the colon carcinoma cells after treatment with selected agents. Apoptosis modulation by RKIP occurred after treatment with doxorubicin, FasL, paclitaxel and TRAIL. TRAIL-treated colon carcinoma cells displayed increased cell death as the levels of RKIP within the cell were increased. In contrast, doxorubicin, FasL and paclitaxel-treated cells displayed a scaffold-like response as the levels of RKIP were increased in the cell; with WT RKIP-expressing cells being more sensitive to doxorubicin, FasL and paclitaxel-induced apoptosis than low or high RKIP-expressing colon carcinoma cells. There was no modulation of 5-FU, cisplatin and etoposide-induced apoptosis by RKIP. Indeed, these three agents did not appear to induce cell death in this colon carcinoma cell line. RKIP modulation of chemo-sensitivity has never been shown before in a colon carcinoma cell line and this is the first time that doxorubicin and FasL-induced apoptosis has been shown to be modulated by RKIP. Further, it is shown here, for the first time, that the modulation of chemotherapy-induced apoptosis by RKIP can change depending upon the cytotoxic drug employed as treatment. TRAIL and FasL, both members of the TNF super-family, were selected for further analysis due to the distinctive cell death responses observed as a consequence of the levels of RKIP within the cell. WT RKIP cells were sensitive to FasL treatment, and high RKIP cells were most sensitive to TRAIL administration. Increased sensitivity of high RKIP-expressing colon cells to TRAIL treatment appeared to involve up-regulation of the DR5 receptor; down-regulation of the anti-apoptotic molecule Bcl-xl; pIKK which activates the NF-κB pathway; and TRAF2 which has been shown to activate the NF-κB pathway. Whether RKIP directly interacts with these molecules is unknown however RKIP has been shown to bind upstream activators of the NF-κB pathway and another TRAF subtype TRAF6. YY1 expression was evident in the TRAIL-treated cells but the expression was unchanged as the levels of RKIP within the cell were altered. The FasL-treated cells also displayed decreased pIKK levels as the levels of RKIP were increased; it is possible that NF-κB was behaving as both pro- and anti-apoptotic within this cell line. Thus RKIP inhibition of the NF-κB pathway may have prevented FasL-induced apoptosis in the high RKIP-expressing colon carcinoma cells. The expression of TRAF6, which has been shown to bind RKIP, displayed a scaffold-like response with WT RKIP-expressing cells having the highest TRAF6 expression. This was also the case for the transcriptional regulator YY1, thus it is possible that both YY1 and TRAF6 were behaving in a pro-apoptotic-like manner in the WT RKIP-expressing cells. TRAF2 was also evident in the FasL-administered cells but the expression did not change regardless of the levels of RKIP within the cell. Overall, it appears that differential expression of TRAF adaptor proteins is responsible for the contrasting responses of TRAIL and FasL-treated cells with low, WT and high RKIP expression. Utilisation of particular TRAF adaptors or TRAF combinations by the TRAIL and Fas receptors may also account for the pro- and anti-apoptotic roles of the NF-κB pathway, and the recruitment or down-regulation of other proteins dependent upon the cell stimulus. How RKIP affects these proteins requires further investigation, however these results are exciting and novel, and strengthen evidence surrounding the role of RKIP in chemosensitivity. On another note, RKIP has been shown to bind the PDE5 inhibitor PF-3717842, therefore investigation of the effects of the PDE5 inhibitors sildenafil citrate and vardenafil citrate on RKIP inhibition of the ERK pathway in a colon carcinoma cell line were examined. The effects of the PDE5 inhibitors were compared to the cell migration inhibitor locostatin that has been shown to bind and inhibit RKIP, and prevent the RKIP-Raf-1 interaction. With TPA and EGF stimulation, locostatin appeared to act in a manner consistent with its known function as an RKIP inhibitor. The PDE5 inhibitors sildenafil citrate and vardenafil citrate displayed a similar trend to that of locostatin, although their effects on the ERK pathway were not as potent. It is possible that after EGF stimulation, the strong activation of B-Raf was over-shadowing the subtle effects of the drug treatments. Under growth conditions, the RKIP inhibitor locostatin did not appear to behave as an inhibitor of RKIP nor did the PDE5 inhibitors sildenafil citrate and vardenafil citrate. It is possible that the strong activation of various growth and proliferative cascades was impinging upon the ERK pathway, were overshadowing the drug effects, or resulting in off-target (RKIP-unrelated) effects of the drugs. In summary, the role of RKIP within the cell is becoming an increasingly exciting avenue of research and is consistently yielding new and interesting roles and interactions within the cell. Understanding and elucidating the roles of this intriguing protein within the cell will not only strengthen our knowledge of signal transduction regulation and modulation, but may also provide a new source of targeted therapy and means of manipulation in the treatment of cancer and chemotherapeutic drug resistance

Doodle Families Manual

This Manual has been designed to support the delivery of the Doodle Families Programme. As well asproviding all the programme content, it details the "how and why" of the sessions, links the practice withtheory, outlines the steps necessary to complete each session and offers background information, tips andsupport to Facilitators in the delivery of the programme. Doodle Families is a Family Literacy Programme, designed to be delivered in two components – one forparents/guardians and the other is for children. Parents' sessions can be delivered during the school day andthe children's sessions are delivered after school

CHILD MALTREATMENT AND NEGATIVE AFFECT STATES: IMPACT ON COGNITION AND DATING VIOLENCE BEHAVIOURS

Maltreated youth are at an increased risk for involvement in aggressive and potentially violent interpersonal relationships, in part due to their limited behavioural and emotion management skills. This study of maltreated adolescents (N = 238; 59.7% female; Mage - 16.41, SDage= 1.02) involved with child protective services (CPS) examined whether: (a) youth have clinical levels of negative affect; (b) the association between adolescent negative affect and adolescent impaired thinking is significant; and (c) there is a link between negative affect, impaired thinking, and engagement in adolescent dating violence. Results showed that maltreated youth reported higher levels of negative affect on the overall psychological symptoms, as well as symptom-specific areas (e.g., trauma, anger), as compared to normative samples. Using an overall negative affect index, few significant associations were found. Negative affect was significantly associated with emotional, physical and sexual abuse (r \u3e .20, p \u3c .01), dating violence victimization (r \u3e ■25, p \u3c .01), dating violence perpetration (r \u3e •25, p \u3c .05) for both males and females. Significant associations between a measure of verbal fluency and maltreatment were limited and varied by gender

“Let’s start with the end of the world, why don’t we?” The Disorienting Phenomenology of N. K. Jemisin’s \u3ci\u3eThe Stone Sky\u3c/i\u3e

N. K. Jemisin’s Broken Earth trilogy made history: each novel won the Best Hugo for Novel (2016-2017-2018). Jemisin is not only the First person to win the novel award three years running, but also the First Black person and the First woman of color to win the novel award. Sony Entertainment purchased the series for adaptation in 2018 (Fleming), and Jemisin will be adapting her series for Film. The Fifth Season has an epic structure (beginning in media res, a quest, world-changing events and characters, and supernatural forces). Given the conventions of the epic genre, my interest in this presentation is how the phenomenological style of Jemisin’s multiple narrative voices, including the use of one second-person and direct address narrator, which intersects with the narrative arc of the female protagonist, a mother, whose epic quest is to save her daughter, subverts reader expectations. My approach, like my earlier publication on Ann Leckie’s Imperial Radch trilogy (Reid), blends linguistics and phenomenology. I use M. A. K. Halliday’s functional grammar to analyze clauses in selected passages (the opening paragraphs of the Prologue and twenty-three chapters in the novel). Phenomenology is the branch of philosophy that focuses on “structures of consciousness as experienced from the first-person point of view” (Stanford). Phenomenological literary studies “regard[s] works of art as mediators between the consciousnesses of the author and the reader or as attempts to disclose aspects of the being of humans and their worlds” (Armstrong). My analysis is informed by Sara Ahmed’s concept of disorientation developed in Queer Phenomenology: Orientations, Objects, Others: When we are orientated, we might not even notice that we are orientated: we might not even think “to think” about this point. When we experience disorientation, we might notice orientation as something we do not have. After all, concepts often reveal themselves as things to think “with” when they fail to be translated into being or action. (Ahmed, 5-6) Ahmed defines queer phenomenology is that which “disorients” the reader, specifically, she defines as “bodily experiences that throw the world up, or throw the body from its ground. Disorientation as a bodily feeling can be unsettling, and it can shatter one’s sense of confidence in the ground” (157). I would argue a trilogy that begins with the implication and claim that “the end of the world” is not the most interesting part of the story, in a Prologue subtitled, “you are here” will disorient the majority of readers, and that disorientation is only the start of Jemisin’s disorienting phenomenology

Liability in Air Travel for Real Estate Agents

Real estate agents who travel are subject to international conventions relating to safety and liability. This article examines the Warsaw Convention and some of the legal issues that arise out of that convention and other Australian legislation including The Civil Aviation (Carriers Liability) Act 1959 (Cth.)

Doodle Den Implementation Guide

This Implementation Guide gives an introduction to Doodle Den, a literacy programme for children, and the recommended steps for starting a new group and delivering the programme. The Doodle Den Manual describes the programme content and acts as a companion to this Implementation Guide