VALPROIC ACID TOXICITY INDUCED BY LACOSAMIDE: A RARE CASE REPORT

Valproic acid is commonly used in the treatment of both focal and generalized epilepsies and is often tolerated well.Valproic acid is usually tolerated well, but serious complications, including hepatotoxicity and hyperammonemic encephalopathy, may occur. Here we report a case of valproic acid induced hyperammonemic encephalopathy on concomitant use with lacosamide.Â

FEBRILE INFECTION-RELATED EPILEPSY SYNDROME: A RARE CASE PRESENTATION

ABSTRACTFebrile infection-related epilepsy syndrome is characterized by super refractory status epilepticus that is resistant to conventional antiepileptic drugs.This case report critically analyses the treatment options adopted in a hospital to manage this syndrome. Despite the aggressive efforts that weretaken, the patient succumbed to the complications of the illness and side effects of the treatment strategies adopted. This shows that the treatmentoptions currently available are in adequate, so an intensive research in the area of pathogenesis of status epilepticus is required to frame treatmentstrategies that can bring out better outcomes.Keywords: Antiepileptics, Febrile infection-related epilepsy syndrome, Status epilepticus

A CASE REPORT ON WILSON'S DISEASE INDUCED LIVER CIRRHOSIS

ABSTRACTWilsons disease is an inherited autosomal genetic abnormality genetic abnormality which results in impairment in cellular copper transport. Overtime this may leads to liver cirrhosis. The main focus of this case is to shows the importance of taking medical history. Here we discuss a case of 35 year old male diagnosed with Wilsons disease induced Liver cirrhosis and portal hypertension. He was physically very weak. Since the same genetic abnormality was the reason for the death of his sibling which was not considered while taking the medical history of this patient, this led to a late diagnosis of 4 years while the patient's condition became worst. Here in we report a case that provides an insight to medical professionals about taking proper medical history of patients.Key Words : Wilsons Disease, Liver Cirrhosis, Copper Deposi