5,743 research outputs found

    Medical Marijuana Laws, Traffic Fatalities, and Alcohol Consumption

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    To date, 16 states have passed medical marijuana laws, yet very little is known about their effects. Using state-level data, we examine the relationship between medical marijuana laws and a variety of outcomes. Legalization of medical marijuana is associated with increased use of marijuana among adults, but not among minors. In addition, legalization is associated with a nearly 9 percent decrease in traffic fatalities, most likely to due to its impact on alcohol consumption. Our estimates provide strong evidence that marijuana and alcohol are substitutes.medical marijuana, traffic fatalities, alcohol consumption

    High on Life? Medical Marijuana Laws and Suicide

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    Using state-level data for the period 1990 through 2007, we estimate the effect of legalizing medical marijuana on suicide rates. Our results suggest that the passage of a medical marijuana law is associated with an almost 5 percent reduction in the total suicide rate, an 11 percent reduction in the suicide rate of 20- through 29-year-old males, and a 9 percent reduction in the suicide rate of 30- through 39-year-old males. Estimates of the relationship between legalization and female suicides are less precise and are sensitive to functional form.medical marijuana laws, marijuana, alcohol, suicide

    Per se drugged driving laws and traffic fatalities

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    The Office of National Drug Control Policy (ONDCP) recently announced a goal of reducing drugged driving by 10 percent within three years. In an effort to achieve this goal, ONDCP is encouraging all states to adopt per se drugged driving laws, which make it illegal to operate a motor vehicle with a controlled substance in the system. To date, 16 states have passed per se drugged driving laws, yet little is known about their effectiveness. The current study examines the relationship between these laws and traffic fatalities, the leading cause of death among Americans ages 5 through 34. Our results provide no evidence that per se drugged driving laws reduce traffic fatalities

    Deployments, Combat Exposure, and Crime

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    During the period 2001-2009, four combat brigades and the 3rd Armored Cavalry Regiment were based at Fort Carson, Colorado. These units were repeatedly deployed during the Iraq War, allowing us to measure the effect of arguably exogenous changes in troop levels on violent crime in El Paso County, where Fort Carson is located. Our results suggest that never-deployed units contributed to community violence in the form of assaults, murders, and robberies. In contrast, estimates of the relationship between the number of previously deployed units and violent crime are generally small and statistically insignificant. We conclude that soldiers returning from combat do not represent a special threat to public safety

    Medical marijuana laws, traffic fatalities, and alcohol consumption

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    To date, 16 states have passed medical marijuana laws, yet very little is known about their effects. Using state-level data, we examine the relationship between medical marijuana laws and a variety of outcomes. Legalization of medical marijuana is associated with increased use of marijuana among adults, but not among minors. In addition, legalization is associated with a nearly 9 percent decrease in traffic fatalities, most likely to due to its impact on alcohol consumption. Our estimates provide strong evidence that marijuana and alcohol are substitutes

    Observation of O+ 4P-4D0 lines in proton aurora over Svalbard

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    Spectra of a proton aurora event show lines of O+ 4P-4D0 multiplet (4639–4696 Å) enhanced relative to the N2 +1N(0,2) compared to normal electron aurora. Conjugate satellite particle measurements are used as input to electron and proton transport models, to show that p/H precipitation is the dominant source of both the O+ and N2 +1N emissions. The emission cross-section of the multiplet in p collisions with O and O2 estimated from published work does not explain the observed O+ brightness, suggesting a higher emission cross-section for low energy p impact on O

    Wet Laws, Drinking Establishments, and Violent Crime

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    Drawing on county-level data from Kansas for the period 1977-2011, we examine whether plausibly exogenous increases in the number of establishments licensed to sell alcohol by the drink are related to violent crime. During this period, 86 out of 105 counties in Kansas voted to legalize the sale of alcohol to the general public for on-premises consumption. We provide evidence that these counties experienced substantial increases in the total number of establishments with on-premises liquor licenses (e.g., bars and restaurants). Using legalization as an instrument, we show that a 10 percent increase in drinking establishments is associated with a 4 percent increase in violent crime. Reduced-form estimates suggest that legalizing the sale of alcohol to the general public for on-premises consumption is associated with an 11 percent increase in violent crime

    High on life? Medical marijuana laws and suicide

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    Using state-level data for the period 1990 through 2007, we estimate the effect of legalizing medical marijuana on suicide rates. Our results suggest that the passage of a medical marijuana law is associated with an almost 5 percent reduction in the total suicide rate, an 11 percent reduction in the suicide rate of 20- through 29-year-old males, and a 9 percent reduction in the suicide rate of 30- through 39-year-old males. Estimates of the relationship between legalization and female suicides are less precise and are sensitive to functional form

    Cosmological quintessence accretion onto primordial black holes : conditions for their growth to the supermassive scale

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    In this work we revisit the growth of small primordial black holes (PBHs) immersed in a quintessential field and/or radiation to the supermassive black hole (SMBHs) scale. We show the difficulties of scenarios in which such huge growth is possible. For that purpose we evaluated analytical solutions of the differential equations (describing mass evolution) and point out the strong fine tuning for that conclusions. The timescale for growth in a model with a constant quintessence flux is calculated and we show that it is much bigger than the Hubble time.The fractional gain of the mass is further evaluated in other forms, including quintessence and/or radiation. We calculate the cosmological density Ω\Omega due to quintessence necessary to grow BHs to the supermassive range and show it to be much bigger than one. We also describe the set of complete equations analyzing the evolution of the BH+quintessence universe, showing some interesting effects such the quenching of the BH mass growth due to the evolution of the background energy. Additional constraints obtained by using the Holographic Bound are also described. The general equilibrium conditions for evaporating/accreting black holes evolving in a quintessence/radiation universe are discussed in the Appendix.Comment: 21 pp., 2 Figures, To appear in IJMP

    The ducky^{2J} Mutation in Cacna2d2 Results in Reduced Spontaneous Purkinje Cell Activity and Altered Gene Expression

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    The mouse mutant ducky and its allele ducky^{2J} represent a model for absence epilepsy characterized by spike-wave seizures and cerebellar ataxia. These mice have mutations in Cacna2d2, which encodes the α₂δ-2 calcium channel subunit. Of relevance to the ataxic phenotype, α₂δ-2 mRNA is strongly expressed in cerebellar Purkinje cells (PCs). The Cacna2d2du2J mutation results in a 2 bp deletion in the coding region and a complete loss of α₂δ-2 protein. Here we show that du^{2J}/du^{2J} mice have a 30% reduction in somatic calcium current and a marked fall in the spontaneous PC firing rate at 22°C, accompanied by a decrease in firing regularity, which is not affected by blocking synaptic input to PCs. At 34°C, du^{2J}/du^{2J} PCs show no spontaneous intrinsic activity. DU^{2J}/du^{2J} mice also have alterations in the cerebellar expression of several genes related to PC function. At postnatal day 21, there is an elevation of tyrosine hydroxylase mRNA and a reduction in tenascin-C gene expression. Although du^{2J}/+ mice have a marked reduction in α₂δ-2 protein, they show no fall in PC somatic calcium currents or increase in cerebellar tryrosine hydroxylase gene expression. However, du^{2J}/+ PCs do exhibit a significant reduction in firing rate, correlating with the reduction in α₂δ-2. A hypothesis for future study is that effects on gene expression occur as a result of a reduction in somatic calcium currents, whereas effects on PC firing occur as a long-term result of loss of α₂δ-2 and/or a reduction in calcium currents and calcium-dependent processes in regions other than the soma
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