The purification and concentration of hog cholera virus.

http://www.worldcat.org/oclc/1094187

Editors’ Introduction: Radical Philosophy and Politics Amid the Climate Crisis and the Coronavirus Pandemic

Editors’ Introduction: Radical Philosophy and Politics Amid the Climate Crisis and the Coronavirus Pandemic for Radical Philosophy Review

The Impacts of Emergency Vehicle Signal Preemption on Urban Traffic Speed

We used GPS data from paratransit vehicles to evaluate the impact of emergency vehicles on urban traffic speeds. The results indicate that speed variance is significantly higher during emergency preemption and the mean speeds of traffic flowing in the same direction as the emergency vehicle and on crossing streets are lower during preemption than during normal conditions. Regression results indicate that traffic on major arterials and traffic in the opposite direction of the emergency vehicle tend to have higher speed during signal preemption. Signal preemption during peak periods and duration of preemption had a significant negative impact on traffic speeds. Also, the transition time has a negative impact on traffic speeds. The authors recommend further research on how to optimize (minimize) the preemption duration as well as transition time. Also, the impact of median type and number of lanes should be evaluated

A study of magnetos

Thesis (BS)--University of Illinois, 1916Typescrip

The response to influenza vaccination is associated with DNA methylation-driven regulation of T cell innate antiviral pathways.

BACKGROUND: The effect of vaccination on the epigenome remains poorly characterized. In previous research, we identified an association between seroprotection against influenza and DNA methylation at sites associated with the RIG-1 signaling pathway, which recognizes viral double-stranded RNA and leads to a type I interferon response. However, these studies did not fully account for confounding factors including age, gender, and BMI, along with changes in cell-type composition. RESULTS: Here, we studied the influenza vaccine response in a longitudinal cohort vaccinated over two consecutive years (2019-2020 and 2020-2021), using peripheral blood mononuclear cells and a targeted DNA methylation approach. To address the effects of multiple factors on the epigenome, we designed a multivariate multiple regression model that included seroprotection levels as quantified by the hemagglutination-inhibition (HAI) assay test. CONCLUSIONS: Our findings indicate that 179 methylation sites can be combined as potential signatures to predict seroprotection. These sites were not only enriched for genes involved in the regulation of the RIG-I signaling pathway, as found previously, but also enriched for other genes associated with innate immunity to viruses and the transcription factor binding sites of BRD4, which is known to impact T cell memory. We propose a model to suggest that the RIG-I pathway and BRD4 could potentially be modulated to improve immunization strategies

Deep Learning based Fast and Accurate Beamforming for Millimeter-Wave Systems

The widespread proliferation of mmW devices has led to a surge of interest in antenna arrays. This interest in arrays is due to their ability to steer beams in desired directions, for the purpose of increasing signal-power and/or decreasing interference levels. To enable beamforming, array coefficients are typically stored in look-up tables (LUTs) for subsequent referencing. While LUTs enable fast sweep times, their limited memory size restricts the number of beams the array can produce. Consequently, a receiver is likely to be offset from the main beam, thus decreasing received power, and resulting in sub-optimal performance. In this letter, we present BeamShaper, a deep neural network (DNN) framework, which enables fast and accurate beamsteering in any desirable 3-D direction. Unlike traditional finite-memory LUTs which support a fixed set of beams, BeamShaper utilizes a trained NN model to generate the array coefficients for arbitrary directions in \textit{real-time}. Our simulations show that BeamShaper outperforms contemporary LUT based solutions in terms of cosine-similarity and central angle in time scales that are slightly higher than LUT based solutions. Additionally, we show that our DNN based approach has the added advantage of being more resilient to the effects of quantization noise generated while using digital phase-shifters.Comment: 7 pages, 5 figures, accepted to Milcom2023. Not published yet(Sep 2023

RSRM Segment Train Derailment and Recovery

On May 2, 2007, a freight train carrying segments of the space shuttle's solid rocket boosters derailed in Myrtlewood, Alabama, after a rail trestle collapsed. The train was carrying Reusable Solid Rocket Motors (RSRM) 98 center and forward segments (STS-120) and RSRM 99 aft segments (STS-122). Initially, it was not known if the segments had been seriously damaged. Four segments dropped approximately 10 feet when the trestle collapsed and one of those four rolled off the track onto its side. The exit cones and the other four segments, not yet on the trestle, remained on solid ground. ATK and NASA immediately dispatched an investigation and recovery team to determine the safety of the situation and eventually the usability of the segments and exit cones for flight. Instrumentation on each segment provided invaluable data to determine the acceleration loads imparted into each loaded segment and exit cone. This paper details the incident, recovery plan and the team work that created a success story that ended with the safe launch of STS120 using the four center segments and the launch of STS122 using the Aft exit cones assemblies

Global, regional, and national estimates of pneumonia burden in HIV-infected children in 2010: a meta-analysis and modelling study

Background: Globally, pneumonia is a leading cause of mortality and morbidity in children younger than 5 years. Underlying HIV infection is an important risk factor for pneumonia morbidity and mortality in children. There are, however, no global or country level estimates of pneumonia burden in HIV-infected children. We assessed the role of HIV in pneumonia incidence and mortality and estimated the number of pneumonia cases and deaths in HIV-infected children younger than 5 years in 133 high pneumonia-burden countries in 2010. Methods: We estimated the risk of hospital admission and case fatality rate caused by pneumonia in HIV-infected children compared with HIV-uninfected children from a systematic review of studies published in Medline, Embase, and Global Health between Jan 1, 1980, and Aug 31, 2013. We estimated nationwide pneumonia incidence and mortality with two different models that incorporated several risk factors for paediatric pneumonia hospital admission and mortality (including HIV infection). We then estimated the number of pneumonia episodes and deaths that occurred in HIV-infected children in 2010. Findings: The odds ratio (OR) for hospital admission for all-cause pneumonia in HIV-infected children compared with HIV-uninfected children was 6·5 (95% CI 5·9–7·2). The risk of death was higher in children with pneumonia and HIV compared with those with pneumonia only (OR 5·9, 95% CI 2·7–12·7). In 2010, 1·4 million pneumonia episodes (uncertainty range [UR] 0·6 million to 3·3 million) and 88 000 pneumonia deaths (UR 47 400–153 000) occurred in HIV-infected children in low-income countries. Of these, 1·2 million pneumonia episodes (UR 0·5 million–2·7 million) and 85 400 deaths (UR 46 000–147 300) were directly attributable to HIV. 1·3 million (90%) pneumonia episodes and 82 400 (93%) pneumonia deaths in HIV-infected children aged younger than 5 years occurred in the WHO African region. Interpretation: Globally, a small proportion of pneumonia episodes and pneumonia deaths occur in HIV-infected children. However, in the highest HIV-burden countries in sub-Saharan Africa (ie, Swaziland, Lesotho, and Zimbabwe) up to a fifth of all pneumonia cases and 60% of pneumonia deaths occur in HIV-infected children. In these countries, major reductions in child pneumonia mortality can be achieved only if the systemic challenges plaguing the health system (poor coverage of early infant testing for HIV, of antiretroviral drugs in pregnant women and young children, of co-trimoxazole prophylaxis, and of pneumococcal vaccination) can be overcome