A light-responsive liposomal agent for MRI contrast enhancement and monitoring of cargo delivery

Medical magnetic resonance imaging (MRI) produces high-resolution anatomical images of the human body, but has limited capacity to provide useful molecular information. The light-responsive, liposomal MRI contrast agent described herein could be used to provide an intrinsic theranostic aspect to MRI and enable tracking the distribution and cargo release of drug delivery systems upon light-triggered activation

Insight into the complete substrate-binding pocket of ThiT by chemical and genetic mutations

Exploring binding opportunities in the pocket of ThiT, a S-component for the transport of thiamine.</p