Innovative use of sweet sorghum juice and syrup in food industry

Sugar is one of the vital ingredients in all types of processed foods. Sugar is also extensively used in the pharmaceutical industry. The price of sugar has been rising during last five years. World trade in sugar is expected to decline by 5%, constrained by reduced export availabilities in several sugar producing countries. As a result, and given a strong global demand, international sugar prices may well remain relatively high and volatile in the coming years1. This is attributed to low cane availability and increased sugar intake in several emerging and developing countries. Hence, the need for suitable sugar alternatives. Sweet sorghum juice, obtained from low water consuming, drought resistant, short duration and seed propagated sweet sorghum, is thus a suitable source to obtain syrup. This syrup can replace sugar in food and pharmaceutical industry applications, thereby reducing its dependence on sugar

Associations between purine metabolites and clinical symptoms in schizophrenia

Background: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology of schizophrenia. Methodology/Principal Findings: Breakdown products in purine pathway were measured using high-pressure liquid chromatography coupled with a coulometric multi-electrode array system for 25 first-episode neuroleptic-naïve patients with schizophrenia at baseline and at 4-weeks following initiation of treatment with antipsychotic medication. Associations between these metabolites and clinical and neurological symptoms were examined at both time points. The ratio of uric acid and guanine measured at baseline predicted clinical improvement following four weeks of treatment with antipsychotic medication. Baseline levels of purine metabolites also predicted clinical and neurological symtpoms recorded at baseline; level of guanosine was associated with degree of clinical thought disturbance, and the ratio of xanthosine to guanosine at baseline predicted degree of impairment in the repetition and sequencing of actions. Conclusions/Significance: Findings suggest an association between optimal levels of purine byproducts and dynamics in clinical symptoms and adjustment, as well as in the integrity of sensory and motor processing. Taken together, alterations in purine catabolism may have clinical relevance in schizophrenia pathology

Presence of Panagrolaimus sp. (Nematoda: Panagrolaimidae) in seeds of pearl millet (Pennisetum americanum (L.) Leeke)

During routine phytosanitary examination of pearl millet seeds at the Plant Quarantine Unit of the International Crops Research Institute for the Semi- Arid Tropics (ICRISAT), Patancheru, Andhra Pradesh, India, we discovered a common soil nematode belonging to the genus Panagrolaimus inside seeds of some of the breeding lines. To date Panagrolaimus spp. have been reported as free living microphagous nematodes, occurring in soil and fresh water (Goodey, 1963), as dyssaprobes (Paramonov, 1962) occurring in roots, stems and leaves also in spikelets (Baranovskaya, 1958) and in rice grains (Panwar & Rao, 1977). Some are endoparasites of insects (Poinar, 1972; Poinar & . Geetha Bai, 1979). This is the first record of a seedborne nematode in pearl millet seeds which is significant in plant quarantine terms

Associations between purine metabolites and monoamine neurotransmitters in first-episode psychosis

Schizophrenia (SZ) is a biochemically complex disorder characterized by widespread defects in multiple metabolic pathways whose dynamic interactions, until recently, have been difficult to examine. Rather, evidence for these alterations has been collected piecemeal, limiting the potential to inform our understanding of the interactions amongst relevant biochemical pathways. We herein review perturbations in purine and neurotransmitter metabolism observed in early SZ using a metabolomic approach. Purine catabolism is an underappreciated, but important component of the homeostatic response of mitochondria to oxidant stress. We have observed a homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with SZ (FENNS). Precursor and product relationships within purine pathways are tightly correlated. Although some of these correlations persist across disease or medication status, others appear to be lost among FENNS suggesting that steady formation of the antioxidant uric acid (UA) via purine catabolism is altered early in the course of illness. As is the case for within-pathway correlations, there are also significant cross-pathway correlations between respective purine and tryptophan (TRP) pathway metabolites. By contrast, purine metabolites show significant cross-pathway correlation only with tyrosine, and not with its metabolites. Furthermore, several purine metabolites (UA, guanosine, or xanthine) are each significantly correlated with 5-hydroxyindoleacetic acid (5-HIAA) in healthy controls, but not in FENNS at baseline or 4-week after antipsychotic treatment. Taken together, the above findings suggest that purine catabolism strongly associates with the TRP pathways leading to serotonin (5-hydroxytryptamine, 5-HT) and kynurenine metabolites. The lack of a significant correlation between purine metabolites and 5-HIAA, suggests alterations in key 5-HT pathways that may both be modified by and contribute to oxidative stress via purine catabolism in FENNS

Seed Systems for Rainfed Agriculture: Village Based Seed Enterprise for Seed Production and Dissemination of Improved Varieties of Chickpea and Pigeonpea in India; Information Bulletin No. 96

The crops grown under rainfed agriculture are described as farming practices that rely on rainfall for crop production and their seed systems describe, how farmers in these regions are sourcing seeds for cultivating these crops. The objective of this publication is to share information and experiences of some success stories of seed value chain models developed for production and supply of improved varieties of seed of rainfed crops to resource poor farmers in the semi-arid tropical regions to enhance productivity. Majority of legume crop varieties grown under rainfed agriculture system are open pollinated varieties or self-pollinated crops especially, cereals and legumes grown in semi-arid tropics of the globe. The importance of rainfed agriculture varies regionally but produces high percentage of food for poor communities in the developing countries. In sub-Saharan Africa more than 95% of the farmed land is rainfed, while the corresponding figure for Latin America is almost 90%, for South Asia it is about 60%, 65% for East Asia and 75% for the Near East and North Africa..

Innovative use of Sweet sorghum juice in the beverage industry

Sweet sorghum juice, obtained from low water consuming, drought resistant, short duration and seed-propagated sweet sorghum crop, was explored as a source to obtain syrup which can be used as sugar alternative for meeting certain requirements of the beverage industry. Value addition, through conversion of the juice to syrup and beverages, offers farmers an excellent opportunity to improve farm income and productivity in semi arid regions. In this study a new method to produce clarified sweet sorghum juice is demonstrated. The sweet sorghum juice was clarified using pre heating followed by vacuum filtration using a filter aid. The clarified juice was concentrated to syrup with acceptable sensory qualities. Flavoured beverage formulations were optimised using the clarified juice and syrup. Nutritional and sensory properties of the developed beverages showed that the samples were acceptable to the consumers and rated at par with a commercially available beverage. This work has immense industrial and social significance

Observations on food and fodder traits in a wide range of cultivars of groundnut.

Dual-purpose usage of gr6undnut in mixed crop livestock systems has prompted collaborative work between groundnut breeders and livestock nutritionists t.o explore opportunities for increasing the fodder value from groundnut haulms without detriment to pod yield: About 800 diverse cultivars of groundnut from ICR1SAT groundnut improvement program groyvn i

Homeostatic Imbalance of Purine Catabolism in First-Episode Neuroleptic-Naïve Patients with Schizophrenia

Background: Purine catabolism may be an unappreciated, but important component of the homeostatic response of mitochondria to oxidant stress. Accumulating evidence suggests a pivotal role of oxidative stress in schizophrenia pathology. Methodology/Principal Findings:Using high-pressure liquid chromatography coupled with a coulometric multi-electrode array system, we compared 6 purine metabolites simultaneously in plasma between first-episode neuroleptic-naïve patients with schizophrenia (FENNS, n = 25) and healthy controls (HC, n = 30), as well as between FENNS at baseline (BL) and 4 weeks (4w) after antipsychotic treatment. Significantly higher levels of xanthosine (Xant) and lower levels of guanine (G) were seen in both patient groups compared to HC subjects. Moreover, the ratios of G/guanosine (Gr), uric acid (UA)/Gr, and UA/Xant were significantly lower, whereas the ratio of Xant/G was significantly higher in FENNS-BL than in HC. Such changes remained in FENNS-4w with exception that the ratio of UA/Gr was normalized. All 3 groups had significant correlations between G and UA, and Xan and hypoxanthine (Hx). By contrast, correlations of UA with each of Xan and Hx, and the correlation of Xan with Gr were all quite significant for the HC but not for the FENNS. Finally, correlations of Gr with each of UA and G were significant for both HC and FENNS-BL but not for the FENNS-4w. Conclusions/Significance: During purine catabolism, both conversions of Gr to G and of Xant to Xan are reversible. Decreased ratios of product to precursor suggested a shift favorable to Xant production from Xan, resulting in decreased UA levels in the FENNS. Specifically, the reduced UA/Gr ratio was nearly normalized after 4 weeks of antipsychotic treatment. In addition, there are tightly correlated precursor and product relationships within purine pathways; although some of these correlations persist across disease or medication status, others appear to be lost among FENNS. Taken together, these results suggest that the potential for steady formation of antioxidant UA from purine catabolism is altered early in the course of illness

Sweet Sorghum: A Smart Crop to Meet the Demands of Food, Fodder, Fuel and Feed

At present, energy demand for transport in India is primarily met through non-renewable energy sources like fossil fuels. Being short in domestic production, India mainly depends on crude oil imports. In the near future oil imports are slated to rise further with no major breakthrough in domestic oil production. A compounding factor is the rise in the number of vehicles on the road, which has grown by 10 % each year between 2001 and 2006, and is expected to rise further. Against this backdrop, there is a renewed interest in energy augmentation through biofuel crops to meet the energy demand in the country. One such promising biofuel crop is sweet sorghum, whose sugar-rich stocks can be crushed to produce juice, then fermented into bio-ethanol, and used to make a blended fuel replacing conventional gasoline (Reddy et al. 2005). Sweet sorghum is a C4 plant with high photosynthetic efficiency. It produces a high biomass (up to 40-50 t ha-1) in a short time (4 months) under rain-fed conditions (Reddy, et al., 2005). One advantage of sweet sorghum compared to other crops is that using sweet sorghum for fuel does not reduce its contribution as food because the grain can be harvested for food, and the bagasse (the fiber left over after extraction of juice from sweet sorghum) that remains after the extraction of juice used for biofuel may be used for fodder (Nalini Kumari et al. 2011). Hence, sweet sorghum is a “smart” crop, which meets the triple requirements of food, fuel and fodde

Sorghum improvement (1980–2010): Status and way forward

Sorghum (Sorghum bicolor) is the fifth most important cereal crop globally and is the dietary staple of more than 500 million people in over 90 countries, primarily in the developing world (Reddy et al. 2010). With its C4 photosynthetic pathway, it is adapted to a wide range of environmental conditions. It has multiple uses as a food, feed, fodder, fuel and fiber crop (Paterson et al. 2009). More than 35 percent of world sorghum production is going for food consumption (Awika and Rooney 2004) by the poorest of the poor in the largely low-income deficit countries. Worldwide, it is grown on about 40 million ha, of which about 9 million ha are cultivated in Asia; of this the largest area is in India (7.53 milion ha) which has a production of 7.25 million t (FAOSTAT 2011)