Distributed utterances

I propose an apparatus for handling intrasentential change in context. The standard approach has problems with sentences with multiple occurrences of the same demonstrative or indexical. My proposal involves the idea that contexts can be complex. Complex contexts are built out of (“simple”) Kaplanian contexts by ordered n-tupling. With these we can revise the clauses of Kaplan’s Logic of Demonstratives so that each part of a sentence is taken in a different component of a complex context. I consider other applications of the framework: to agentially distributed utterances (ones made partly by one speaker and partly by another); to an account of scare-quoting; and to an account of a binding-like phenomenon that avoids what Kit Fine calls “the antinomy of the variable.

Team Reasoning and Collective Intentionality

Different versions of the idea that individualism about agency is the root of standard game theoretical puzzles have been defended by Regan 1980, Bacharach (Research in Economics 53: 117–147, 1999), Hurley (Behavioral and Brain Sciences 26: 264–265, 2003), Sugden (Philosophical Explorations 6(3):165–181, 2003), and Tuomela 2013, among others. While collectivistic game theorists like Michael Bacharach provide formal frameworks designed to avert some of the standard dilemmas, philosophers of collective action like Raimo Tuomela aim at substantive accounts of collective action that may explain how agents overcoming such social dilemmas would be motivated. This paper focuses on the conditions on collective action and intention that need to be fulfilled for Bacharach’s “team reasoning” to occur. Two influential approaches to collective action are related to the idea of team reasoning: Michael Bratman’s theory of shared intention and Raimo Tuomela’s theory of a we-mode of intending. I argue that neither captures the “agency transformation” that team reasoning requires. That might be an acceptable conclusion for Bratman but more problematic for Tuomela, who claims that Bacharach’s results support his theory. I sketch an alternative framework in which the perspectival element that is required for team reasoning - the ‘we-perspective’ - can be understood and functionally characterized in relation to the traditional distinction between mode and content of intentional states. I claim that the latter understanding of a collective perspective provides the right kind of philosophical background for team reasoning, and I discuss some implications in relation to Tuomela’s assumption that switching between individual and collective perspectives can be a matter of rational choice

Descripción Sensorial Cuantitativa de la Miel de Acacia

En este trabajo se describen las características sensoriales de la miel de acacia. La descripción sensorial cuantitativa fue realizada por un panel, previamente seleccionado y entrenado de acuerdo al procedimiento establecido en IRAM 20005, constituido por cinco hombres y cuatro mujeres de edades comprendidas entre 20 y 30 años, pertenecientes a la comunidad académica de la UTN FRRo. Una vez garantizado el desempeño de los miembros del panel, se realizó el análisis descriptivo de dicha miel, en condiciones controladas de laboratorio. Los atributos analizados fueron intensidad del olor y del color, aroma, fluidez, dulzor, granulosidad, persistencia, cantidad y tamaño de cristales. Las mieles de acacia presentaron dulzor entre moderado e intenso, color ámbar claro sin notas características, olor moderado con notas vegetales, cálidas y florales, mientras que la persistencia resultó entre baja y media. El perfil obtenido contribuye a caracterizar la miel en relación a su origen floral, constituyendo una herramienta de diferenciación, que aumenta su valor agregado a la hora de comercializarl

Rich Situated Attitudes

We outline a novel theory of natural language meaning, Rich Situated Semantics [RSS], on which the content of sentential utterances is semantically rich and informationally situated. In virtue of its situatedness, an utterance’s rich situated content varies with the informational situation of the cognitive agent interpreting the utterance. In virtue of its richness, this content contains information beyond the utterance’s lexically encoded information. The agent-dependence of rich situated content solves a number of problems in semantics and the philosophy of language (cf. [14, 20, 25]). In particular, since RSS varies the granularity of utterance contents with the interpreting agent’s informational situation, it solves the problem of finding suitably fine- or coarse-grained objects for the content of propositional attitudes. In virtue of this variation, a layman will reason with more propositions than an expert

Relevance theory, pragmatic inference and cognitive architecture

Relevance Theory (RT: Sperber & Wilson, 1986) argues that human language comprehension processes tend to maximize “relevance”, and postulates that there is a relevance-based procedure that a hearer follows when trying to understand an utterance. Despite being highly influential, RT has been criticized for its failure to explain how speaker-related information, either the speaker’s abilities or her/his preferences, is incorporated into the hearer’s inferential, pragmatic process. An alternative proposal is that speaker-related information gains prominence due to representation of the speaker within higher-level goal-directed schemata. Yet the goal-based account is still unable to explain clearly how cross-domain information, for example linguistic meaning and speaker-related knowledge, is integrated within a modular system. On the basis of RT’s cognitive requirements, together with contemporary cognitive theory, we argue that this integration is realized by utilizing working memory and that there exist conversational constraints with which the constructed utterance interpretation should be consistent. We illustrate our arguments with a computational implementation of the proposed processes within a general cognitive architecture

The metaphysics of mental files

There is much to be said for a diachronic or interpersonal individuation of singular modes of presentation (MOPs) in terms of a criterion of epistemic transparency between thought tokens. This way of individuating MOPs has been discussed recently within the mental files framework, though the issues discussed here arise for all theories that individuate MOPs in terms of relations among tokens. All such theories face objections concerning apparent failures of the transitivity of the ‘same MOP’ relation. For mental files, these transitivity failures most obviously occur because mental files can merge or undergo fission. In this paper I argue that this problem is easily resolved once mental files are properly construed as continuants, whose metaphysics is analogous to that of persons or physical objects. All continuants can undergo fission or fusion, leading to similar transitivity problems, but there are well-established theories of persistence that accommodate this. I suggest that, in particular, the stage theory best suits the purposes of a continuant theory of MOPs.PostprintPeer reviewe

Regulation of Respiration and Apoptosis by Cytochrome c Threonine 58 Phosphorylation

Cytochrome c (cytc) is a multifunctional protein, acting as an electron carrier in the electron transport chain (ETC), where it shuttles electrons from bc1 complex to cytochrome c oxidase (COX), and as a trigger of type II apoptosis when released from the mitochondria. We previously showed that cytc is regulated in a highly tissue-specific manner: Cytc isolated from heart, liver, and kidney is phosphorylated on Y97, Y48, and T28, respectively. Here, we have analyzed the effect of a new Cytc phosphorylation site, threonine 58, which we mapped in rat kidney Cytc by mass spectrometry. We generated and overexpressed wild-type, phosphomimetic T58E, and two controls, T58A and T58I cytc; the latter replacement is found in human and testis-specific Cytc. In vitro, COX activity, caspase-3 activity, and heme degradation in the presence of H2o2 were decreased with phosphomimetic Cytc compared to wild-type. Cytc-knockout cells expressing T58E or T58I Cytc showed a reduction in intact cell respiration, mitochondrial membrane potential (∆Ψm), ROS production, and apoptotic activity compared to wild-type. We propose that, under physiological conditions, Cytc is phosphorylated, which controls mitochondrial respiration and apoptosis. Under conditions of stress Cytc phosphorylations are lost leading to maximal respiration rates, ∆Ψm hyperpolarization, ROS production, and apoptosis