Signalling C-Type Lectins in Antimicrobial Immunity

Funding: This work was funded by the Wellcome Trust, Medical Research Council and the University of Aberdeen. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublisher PD

The response of tropospheric circulation to perturbations in lower-stratospheric temperature

A multiple regression analysis of the NCEP-NCAR reanalysis dataset shows a response to increased solar activity of a weakening and poleward shift of the subtropical jets. This signal is separable from other influences, such as those of El Nino-Southern Oscillation (ENSO) and the North Atlantic Oscillation (NAO), and is very similar to that seen in previous studies using global circulation models (GCMs) of the effects of an increase in solar spectral irradiance. The response to increased stratospheric (volcanic) aerosol is found in the data to be a weakening and equatorward shift of the jets. The GCM studies of the solar influence also showed an impact on tropospheric mean meridional circulation with a weakening and expansion of the tropical Hadley cells and a poleward shift of the Ferrel cells. To understand the mechanisms whereby the changes in solar irradiance affect tropospheric winds and circulation, experiments have been carried out with a simplified global circulation model. The results show that generic heating of the lower stratosphere tends to weaken the subtropical jets and the tropospheric mean meridional circulations. The positions of the jets, and the extent of the Hadley cells, respond to the distribution of the stratospheric heating, with low-latitude heating forcing them to move poleward, and high-latitude or latitudinally uniform heating forcing them equatorward. The patterns of response are similar to those that are found to be a result of the solar or volcanic influences, respectively, in the data analysis. This demonstrates that perturbations to the heat balance of the lower stratosphere, such as those brought about by solar or volcanic activity, can produce changes in the mean tropospheric circulation, even without any direct forcing below the tropopause

Distributed Computing with Adaptive Heuristics

We use ideas from distributed computing to study dynamic environments in which computational nodes, or decision makers, follow adaptive heuristics (Hart 2005), i.e., simple and unsophisticated rules of behavior, e.g., repeatedly "best replying" to others' actions, and minimizing "regret", that have been extensively studied in game theory and economics. We explore when convergence of such simple dynamics to an equilibrium is guaranteed in asynchronous computational environments, where nodes can act at any time. Our research agenda, distributed computing with adaptive heuristics, lies on the borderline of computer science (including distributed computing and learning) and game theory (including game dynamics and adaptive heuristics). We exhibit a general non-termination result for a broad class of heuristics with bounded recall---that is, simple rules of behavior that depend only on recent history of interaction between nodes. We consider implications of our result across a wide variety of interesting and timely applications: game theory, circuit design, social networks, routing and congestion control. We also study the computational and communication complexity of asynchronous dynamics and present some basic observations regarding the effects of asynchrony on no-regret dynamics. We believe that our work opens a new avenue for research in both distributed computing and game theory.Comment: 36 pages, four figures. Expands both technical results and discussion of v1. Revised version will appear in the proceedings of Innovations in Computer Science 201

Environmental effects of the Manganui ski field, Mt Taranaki/Egmont

During May 2012, the environmental effects of the Manganui ski field were examined. Permanent quadrats first established in 1974 to monitor vegetation changes were re-measured, vegetation mapping was conducted, modifications to ground form and drainage were identified, soil compaction was examined, and stream water from the ski field catchment was tested for nutrient enrichment. This report focusses primarily on the lower Manganui ski field, as the upper Manganui ski field consists mostly of unmodified herbfield or gravelfield, protected by a sufficient snow base over the winter months. The lower Manganui ski field has a long history of modification spanning from the early 1900s. Vegetation types mapped on the lower field included unmown tussockfield, mown tussock-herbfield, shrubland and exotics. The re-measurement of vegetation in permanent quadrats on the lower field suggests that since the last re-measurement in 1994, several exotic species have increased in cover, including Carex ovalis, Poa annua, and Agrostis capillaris (percentage cover increases of up to 46.6%, 42.0% and 20.7% respectively). Vegetation mapping and historic photographs indicate that the lower ski field sits within the elevational belt of shrubland vegetation, little of which remains due to regular mowing conducted on the field since 1947. Shrubs which have been largely excluded from the field through mowing include Brachyglottis elaeagnifolius, Hebe odora, Ozothamnus vauvilliersii, Dracophyllum filifolium, Pseudopanax colensoi, Raukaua simplex and Hebe stricta var. egmontiana. Areas of the ski field dominated by exotic vegetation were predominantly associated with historic culvert construction and rock dynamiting. Compaction by machinery was confined to the sensitive mossfield area at the base of the lower field

Impacts of harmonic distortion from charging electric vehicles on low voltage networks

Paper focusing on the impacts of harmonic distortion from charging electric vehicles on low voltage networks