2,915 research outputs found
Role of Air in Granular Jet Formation
A steel ball impacting on a bed of very loose, fine sand results in a surprisingly vigorous jet which shoots up from the surface of the sand [D. Lohse et al., Phys. Rev. Lett. 93, 198003 (2004)]. When the ambient pressure p is reduced, the jet is found to be less vigorous [R. Royer et al., Nature Phys. 1, 164 (2005)]. In this Letter we show that p also affects the rate of penetration of the ball: Higher pressure increases the rate of penetration, which makes the cavity created by the ball close deeper into the sand bed, where the hydrostatic pressure is stronger, thereby producing a more energetic collapse and jetting. The origin of the deeper penetration under normal ambient pressure is found to lie in the extra sand fluidization caused by the air flow induced by the falling ball
Bubble Pinch-Off in a Rotating Flow
We create air bubbles at the tip of a âbathtub vortexâ which reaches to a finite depth. The bathtub vortex is formed by letting water drain through a small hole at the bottom of a rotating cylindrical container. The tip of the needlelike surface dip is unstable at high rotation rates and releases bubbles which are carried down by the flow. Using high-speed imaging we find that the minimal neck radius of the unstable tip decreases in time as a power law with an exponent close to 1/3. This exponent was found by Gordillo et al. [Phys. Rev. Lett. 95, 194501 (2005)] to govern gas flow driven pinch-off, and indeed we find that the volume oscillations of the tip creates a considerable air flow through the neck. We argue that the Bernoulli pressure reduction caused by this air flow can become sufficient to overcome the centrifugal forces and cause the final pinch-off
Controlled impact of a disk on a water surface: Cavity dynamics
In this paper we study the transient surface cavity which is created by the
controlled impact of a disk of radius h0 on a water surface at Froude numbers
below 200. The dynamics of the transient free surface is recorded by high speed
imaging and compared to boundary integral simulations. An excellent agreement
is found between both. The flow surrounding the cavity is measured with high
speed particle image velocimetry and is found to also agree perfectly with the
flow field obtained from the simulations. We present a simple model for the
radial dynamics of the cavity based on the collapse of an infinite cylinder.
This model accounts for the observed asymmetry of the radial dynamics between
the expansion and contraction phase of the cavity. It reproduces the scaling of
the closure depth and total depth of the cavity which are both found to scale
roughly proportional to Fr^{1/2} with a weakly Froude number dependent
prefactor. In addition, the model accurately captures the dynamics of the
minimal radius of the cavity, the scaling of the volume Vbubble of air
entrained by the process, namely Vbubble/h0^3 proportional (1 +
0.26Fr^{1/2})Fr^{1/2}, and gives insight into the axial asymmetry of the
pinch-off process.Comment: 34 pages, 17 figures, submitted to the Journal of Fluid Mechanics.
Figure quality was reduced considerably and converted to greyscale to
decrease file siz
Mapping Seyfert and LINER Excitation Modes in the Inner kpc of NGC 3393
We have mapped the extended narrow line region (ENLR) of NGC 3393 on scales
of (kpc) from the nucleus using emission
line images of H, [O III], and [S
II] taken with HST as part of the CHandra survey of
Extended Emission line Regions in nearby Seyfert galaxies (CHEERS). By mapping
these lines onto a spatially resolved Baldwin-Phillips-Terlevich (BPT) diagram,
we investigate the impact of feedback from a Compton-thick AGN on its
circumnuclear ISM. We find the expected Seyfert-like emission within the
ionization bicone (; 770 pc). We also find a new,
figure 8 shaped LINER cocoon enveloping the bicone and defining a sharp
(pc) transition between higher and lower ionization zones. These
data illustrate the morphological dependence of ionization states of the ENLR
relative to bicone and host gas geometries.Comment: Accepted by ApJ and published (2016, ApJ, 829, 46). Updated to
reflect the accepted versio
Non-continuous Froude number scaling for the closure depth of a cylindrical cavity
A long, smooth cylinder is dragged through a water surface to create a cavity
with an initially cylindrical shape. This surface void then collapses due to
the hydrostatic pressure, leading to a rapid and axisymmetric pinch-off in a
single point. Surprisingly, the depth at which this pinch-off takes place does
not follow the expected Froude power-law. Instead, it displays two
distinct scaling regimes separated by discrete jumps, both in experiment and in
numerical simulations (employing a boundary integral code). We quantitatively
explain the above behavior as a capillary waves effect. These waves are created
when the top of the cylinder passes the water surface. Our work thus gives
further evidence for the non-universality of the void collapse
Pediatric Kawasaki Disease and Adult Human Immunodeficiency Virus Kawasaki-Like Syndrome Are Likely the Same Malady.
Background.âPediatric Kawasaki disease (KD) and human immunodeficiency virus (HIV)+ adult Kawasaki-like syndrome (KLS) are dramatic vasculitides with similar physical findings. Both syndromes include unusual arterial histopathology with immunoglobulin (Ig)A+ plasma cells, and both impressively respond to pooled Ig therapy. Their distinctive presentations, histopathology, and therapeutic response suggest a common etiology. Because blood is in immediate contact with inflamed arteries, we investigated whether KD and KLS share an inflammatory signature in serum.Methods.âA custom multiplex enzyme-linked immunosorbent assay (ELISA) defined the serum cytokine milieu in 2 adults with KLS during acute and convalescent phases, with asymptomatic HIV+ subjects not taking antiretroviral therapy serving as controls. We then prospectively collected serum and plasma samples from children hospitalized with KD, unrelated febrile illnesses, and noninfectious conditions, analyzing them with a custom multiplex ELISA based on the KLS data.Results.âPatients with KLS and KD subjects shared an inflammatory signature including acute-phase reactants reflecting tumor necrosis factor (TNF)-α biologic activity (soluble TNF receptor I/II) and endothelial/smooth muscle chemokines Ccl1 (Th2), Ccl2 (vascular inflammation), and Cxcl11 (plasma cell recruitment). Ccl1 was specifically elevated in KD versus febrile controls, suggesting a unique relationship between Ccl1 and KD/KLS pathogenesis.Conclusions.âThis study defines a KD/KLS inflammatory signature mirroring a dysfunctional response likely to a common etiologic agent. The KD/KLS inflammatory signature based on elevated acute-phase reactants and specific endothelial/smooth muscle chemokines was able to identify KD subjects versus febrile controls, and it may serve as a practicable diagnostic test for KD
Autism screening at 18Â months of age: a comparison of the Q-CHAT-10 and M-CHAT screeners.
Funder: Peterborough NHS Foundation TrustFunder: Collaboration for Leadership in Applied Health Research and Care - Greater ManchesterFunder: NIHR Cambridge Biomedical Research CentreBACKGROUND: Autism screening is recommended at 18- and 24-month pediatric well visits. The Modified Checklist for Autism in Toddlers-Revised (M-CHAT-R) authors recommend a follow-up interview (M-CHAT-R/F) when positive. M-CHAT-R/F may be less accurate for 18-month-olds than 24-month-olds and accuracy for identification prior to two years is not known in samples that include children screening negative. Since autism symptoms may emerge gradually, ordinally scoring items based on the full range of response options, such as in the 10-item version of the Quantitative Checklist for Autism in Toddlers (Q-CHAT-10), might better capture autism signs than the dichotomous (i.e., yes/no) items in M-CHAT-R or the pass/fail scoring of Q-CHAT-10 items. The aims of this study were to determine and compare the accuracy of the M-CHAT-R/F and the Q-CHAT-10 and to describe the accuracy of the ordinally scored Q-CHAT-10 (Q-CHAT-10-O) for predicting autism in a sample of children who were screened at 18 months. METHODS: This is a community pediatrics validation study with screen positive (nâ=â167) and age- and practice-matched screen negative children (nâ=â241) recruited for diagnostic evaluations completed prior to 2 years old. Clinical diagnosis of autism was based on results of in-person diagnostic autism evaluations by research reliable testers blind to screening results and using the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2) Toddler Module and Mullen Scales of Early Learning (MSEL) per standard guidelines. RESULTS: While the M-CHAT-R/F had higher specificity and PPV compared to M-CHAT-R, Q-CHAT-10-O showed higher sensitivity than M-CHAT-R/F and Q-CHAT-10. LIMITATIONS: Many parents declined participation and the sample is over-represented by higher educated parents. Results cannot be extended to older ages. CONCLUSIONS: Limitations of the currently recommended two-stage M-CHAT-R/F at the 18-month visit include low sensitivity with minimal balancing benefit of improved PPV from the follow-up interview. Ordinal, rather than dichotomous, scoring of autism screening items appears to be beneficial at this age. The Q-CHAT-10-O with ordinal scoring shows advantages to M-CHAT-R/F with half the number of items, no requirement for a follow-up interview, and improved sensitivity. Yet, Q-CHAT-10-O sensitivity is less than M-CHAT-R (without follow-up) and specificity is less than the two-stage procedure. Such limitations are consistent with recognition that screening needs to recur beyond this age
Mapping Seyfert and LINER excitation modes in the inner kpc of NGC 3393
We mapped the extended narrowline region (ENLR) of NGC 3393 on scales of r 4 (~1 kpc) from the nucleus using emission line images of Hα λ6563, [O III]l5007, and [S II]ll6717, 6731, taken with the Hubble Space Telescope as part of the CHandra survey of Extended Emission line Regions in nearby Seyfert galaxies (CHEERS). By mapping these lines onto a spatially resolved BaldwinâPhillipsâTerlevich diagram, we investigate the impact of feedback from a Compton-thick active galactic nucleus on its circumnuclear ISM. We find that the expected Seyfert-like emission within the ionization bicone (3; 770 pc). We also find a new, figure-8-shaped low ionization emission line region (LINER) cocoon enveloping the bicone and defining a sharp (100 pc) transition between higher and lower-ionization zones. These data illustrate the morphological dependence of ionization states of the ENLR relative to bicone and host gas geometries
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