6 research outputs found
Play in the language class
Play is an indispensable part of our physical, mental,
and social development. While including play in
my teaching, I have found that play enhances
the abilities to listen, respect rules decided upon
and have control over one’s emotions. To make
my language class lively, I took the support of
language games that can increase the comfort
and confidence of learners in the acquisition
of the English language and give them ample
opportunities to make mistakes, experience, learn
and apply when and where needed. The advantage
of playing a language game is that learners do not
feel disappointed about losing because everyone
is in the same phase of learning. Also, as most
children cannot help correcting each other,
learners get quick peer feedback. As a teacher, it
is my responsibility to provide my students with
the best possible resources. I am sharing a few of
my experiences of using language games in the
classroom
Walking an unknown path : online learning
We are undergoing a crisis in the present times. The
pandemic has totally upended the lives of people –
the lockdown and its restrictions, social distancing
and the closing of schools! The question that arose
for us, teachers was: how we can connect with
our students from afar, that too in a situation of
uncertainty, mistrust and fear generated due to this
mysterious virus? Learning had to continue and at
first thought, the engagement over a distance mode
came out to us as an instant possibility. At the same
time, we had to anticipate the possible structure
of the classroom in distance mode, something that
was unknown terrain for all of us in the school
EGFR scoring in head and neck squamous cell carcinoma and its association with clinicopathological variables
Background: Head and Neck squamous cell carcinoma (HNSCC) is the seventh most common cancer in the world with poor overall survival rate which is unchanged during the last two decades.
Aim: Aim of our study is to measure the level of Epidermal Growth Factor Receptor (EGFR) expression in HNSCC by immunohistochemistry (IHC) and to correlate EGFR with clinicopathological variables.
Settings and Design: Cross sectional study from 1st October 2012 to 31st of March 2014 was performed.
Materials and Methods: After taking detailed history and a thorough examination, biopsy/ specimen of HNSCC region were evaluated to confirm the diagnosis of HNSCC. Paraffin blocks of such tumors were processed for EGFR staining. Staining intensity was evaluated by using scale from 1 to 4.
Statistical Analysis: Chi-square test was used as appropriate for data analysis.
Results: In the present study 38/50 (78%) patients were diagnosed as well differentiated, 12/50(24%) were diagnosed as moderately differentiated. For EGFR staining, 24/50 (48%) scored as +2, 16/50(32%) as +3, 8/50(16%) as +1 and 2/50(4%) scored as 0. 23/38(60.5%) well differentiated SCC cases presented as +2, 5/38(13.2%) as +3, 8/38(21.1%) as +1 and 2/38(5.3%) as 0. 11/12(91.6%) moderately differentiated SCC cases were scored as +3, 1/12(8.3%) as +2. p value 0.001, which is highly significant. However, correlation of EGFR scoring with patients age, sex, addiction history, site of the tumor was insignificant.
Conclusion: EGFR was highly expressed in HNSCC. The result of our study showed that, high EGFR scoring was associated with high grade of the tumor. There was no significant relationship between EGFR scoring and clinicopathological variables