A new anti-feedant clerodane diterpenoid from tinospora cordifolia

Phytochemical investigation of the chloroform extract of Tinospora cordifolia yielded a new clerodane diterpenoid tincordin (1) along with tinosporide (2), 8-hydroxytinosporide (3), columbin (4), 8-hydroxycolumbin (5) and 10-hydroxycolumbin (6). The structure of the new compound was elucidated comprehensively using 1D and 2D NMR methods. All major clerodane diterpenoids isolated were tested for their efficacy as insect antifeedants against Earias vitella, Plutella xylostella and Spodoptera litura.Department of Science and Technology, Government of Indi