63 research outputs found

    The Cosmic Ray ^3He/^4He Ratio from 200 MeV per Nucleon^(-1) to 3.7 GeV per Nucleon^(-1)

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    The abundances of cosmic-ray helium isotopes between 0.2 and 3.7 GeV nucleon^(-1) were measured by the Isotope Matter Antimatter Experiment (IMAX) during a flight from Lynn Lake, Manitoba, Canada on 1992 July 16-17. The IMAX balloon-borne magnetic spectrometer realized a direct measurement of the charge, the velocity, and the rigidity of cosmic rays using plastic scintillators, a high-resolution time-of-flight system, and two silica-aerogel Cerenkov counters in conjunction with a drift chamber/multiwire proportional chamber tracking system. About 75,000 helium isotopes are identified by their mass using the velocity versus magnetic rigidity technique. The measured ^3He/^4He ratios are corrected to the top of the atmosphere, and a comparison with previous data is given. The observed isotopic composition is found to be generally consistent with the predictions of a standard leaky box model of cosmic-ray transport in the Galaxy

    The Cosmic Ray ^3He/^4He Ratio from 200 MeV/nucleon^(-1) to 3.7 GeV/nucleon^(-1)

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    The abundances of cosmic-ray helium isotopes between 0.2 and 3.7 GeV nucleon^(-1) were measured by the Isotope Matter Antimatter Experiment (IMAX) during a flight from Lynn Lake, Manitoba, Canada on 1992 July 16-17. The IMAX balloon-borne magnetic spectrometer realized a direct measurement of the charge, the velocity, and the rigidity of cosmic rays using plastic scintillators, a high-resolution time-of-flight system, and two silica-aerogel Cerenkov counters in conjunction with a drift chamber/multiwire proportional chamber tracking system. About 75,000 helium isotopes are identified by their mass using the velocity versus magnetic rigidity technique. The measured ^3He/^4He ratios are corrected to the top of the atmosphere, and a comparison with previous data is given. The observed isotopic composition is found to be generally consistent with the predictions of a standard leaky box model of cosmic-ray transport in the Galaxy

    Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models

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    Test-retest reliability and practice effects of a rapid screen of mild traumatic brain injury

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    Test-retest reliabilities and practice affects of measures from the Rapid Screen of Concussion (RSC), in addition to the Digit Symbol Substitution Test (Digit Symbol), were examined. Twenty five male participants were tested three times; each testing session scheduled a week apart. The test-retest reliability estimates for most measures were reasonably good, ranging from .79 to .97. An exception was the delayed word recall test, which has had a reliability estimate of .66 for the first retest, and .59 for the second retest. Practice effects were evident from Times 1 to 2 on the sentence comprehension and delayed recall subtests of the RSC, Digit Symbol and a composite score. There was also a practice effect of the same magnitude found from Time 2 to Time 3 on Digit Symbol, delayed recall and the composite score. Statistics on measures for both the first and second retest intervals, with associated practice affects, are presented to enable the calculation of reliable change indices (RCI). The RCI may be used to assess any improvement in cognitive functioning after mild Traumatic Brain Injury

    Characterization of Human Cytomegalovirus Strains by Analysis of Short Tandem Repeat Polymorphisms

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    Human cytomegalovirus (HCMV) strains display genetic polymorphisms, and these polymorphisms can be analyzed to study viral transmission and pathogenesis. Recently, short tandem repeat (STR) length polymorphisms have been identified in the HCMV genome. We assessed the utility of STRs in characterizing HCMV strains and found that a multiplexed PCR assay using primers based upon these STRs accurately maps HCMV strains. Using primers for 10 microsatellite regions, the STR profiles of 44 wild-type and 2 laboratory strains of HCMV were characterized. The results of STR analysis were compared with those for strain characterization using nucleotide sequencing and restriction fragment length polymorphism analysis. In each instance, STR analysis accurately and specifically identified strains that were indistinguishable or distinct by conventional molecular analysis. Analysis of short tandem repeats also detected polymorphisms that supported simultaneous excretion of two HCMV strains. These results indicate that STR analysis allows rapid, precise molecular characterization of HCMV strains
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