22 research outputs found

    Next generation sequencing (NGS) database for tandem repeats with multiple pattern 2°-shaft multicore string matching

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    Next generation sequencing (NGS) technologies have been rapidly applied in biomedical and biological research in recent years. To provide the comprehensive NGS resource for the research, in this paper , we have considered 10 loci/codi/repeats TAGA, TCAT, GAAT, AGAT, AGAA, GATA, TATC, CTTT, TCTG and TCTA. Then we developed the NGS Tandem Repeat Database (TandemRepeatDB) for all the chromosomes of Homo sapiens, Callithrix jacchus, Chlorocebus sabaeus, Gorilla gorilla, Macaca fascicularis, Macaca mulatta, Nomascus leucogenys, Pan troglodytes, Papio anubis and Pongo abelii genome data sets for all those locis. We find the successive occurence frequency for all the above 10 SSR (simple sequence repeats) in the above genome data sets on a chromosome-by-chromosome basis with multiple pattern 2° shaft multicore string matching. Keywords: NGS, SSR, TandemRepeatDB, Genome, String matching, chromosome

    Similarity analysis between chromosomes of Homo sapiens and monkeys with correlation coefficient, rank correlation coefficient and cosine similarity measures

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    In this paper, we consider correlation coefficient, rank correlation coefficient and cosine similarity measures for evaluating similarity between Homo sapiens and monkeys. We used DNA chromosomes of genome wide genes to determine the correlation between the chromosomal content and evolutionary relationship. The similarity among the H. sapiens and monkeys is measured for a total of 210 chromosomes related to 10 species. The similarity measures of these different species show the relationship between the H. sapiens and monkey. This similarity will be helpful at theft identification, maternity identification, disease identification, etc. Keywords: Correlation coefficient, Rank correlation coefficient, Cosine similarity, DNA, Chromosome

    Mass spectral study of substituted methyl (E)-and (Z)-cinnamates under 1,2-dibromoethane chemical ionization

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    Dibromoethane chemical ionization mass spectra of ten pairs of methyl (E)- and (Z)-cinnamates were studied. C2H4Br+ ion forms stable adducts with E-isomers and the adducts of Z-isomers show preferential loss of methanol. The observed results suggest that the probability of ring alkylation is greater than with the carbonyl group

    Extragonadal endodermal sinus tumour of teilum report of two cases and review of literature

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    A 2-year perineal swelling of a 4-year-old girl and a 2-month swelling in the abdomen of a 1 year-old boy were found to be endodermal sinus tumours of Teilum. The gonads were normal in both. The histological appearance was typical with epithelial and stromal combinations and glomerulus-like structures called Schiller-Duval bodies. A brief review of the literature on the origin of these tumours is given. The girl is still alive but the boy died 2 days after laparotomy

    Negative ion chemical ionization (Cl<SUP>-</SUP>) mass spectra of amino acids

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    Negative ion chemical ionization (Cl-) mass spectra of the commonly occurring amino acids are simple and give information regarding molecular weight by the presence of [M + Cl]- adduct in the case of simple amino acids and [M - H]- in the case of amino acids containing additional polar groups. tert-Butyloxycarbonyl (BOC)-protected di-, tri- and tetrapeptides also given abundant [M + Cl]- ions
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