A study of concentration of sugar mill effluents on properties of soil and types of micro-organisms present in the soil

 The work was undertaken to assess the effect of various concentrations like 0%, 25%, 50% and 100% of sugar mill effluents (SME) on soil properties and types of micro-oranisms present were also studied. With increased concentration of SME causes increase in Total Organic Carbon (TOC), pH, Electrical Conductivity (EC), Ca+2, Mg+2 etc. of the soil.Keywords: Sugar mill effluents, micro-organisms, Total Organic Carbon (TOC), Electrical Conductivity (EC)

Pengaruh Implementasi Special Economic Zone Batam Bintan Karimun terhadap Peningkatan Industri Pariwisata di Kabupaten Bintan pada Tahun 2012-2014

The research present describe the influence of implementation Special Economic Zone in Batam Bintan Karimun towards increase of tourism industry in Bintan Regency in 2012-2014. Special economic zone are dealed in 2007, before implementation special economic zone, Batam are the teritory that implemented of free trade zone. Implementation of special economic zone have purpose to increase a economic growth in teritory border especially for Batam Bintan Karimun.The research use the methode are qualitative methodes that analyze problem research by describe the subject and object conditions based on real fact. This research use location in Bintan Regency and researcher collect data from books, government regulation, journal, mass media, website. This research use neo liberalism perspective with the concept of tourism.The conclusion of this research are influence of implementation Special Economic Zone in Batam Bintan Karimun towards tourism in Bintan Regency are increase of transprotation in Bintan such as road, bridge and airport, and increase of investations value and international tourism event in integrated tourism Lagoi area likes Bintan Triathlon, Tour de Bintan, Fishing Festival and Bintan Mountain Trecking and Durian Party.Keywords: influence, implementation, special economic and tourism

Correlaction of Protein Intake, Consumption of Fruit and Vegetables, Sodium Intake in Packaged Food with the Incidence of Anemia

Anemia among adolescents is still an important health problem due to adolescent growth. Anemia in adolescent girls is caused by irregular eating patterns, abstinence from eating eggs/meat/fish, a dislike of consuming vegetables, and eating habits of fast food and junk food. Objective: This study aims to determine the relationship between protein, vegetable, and fruit intake, and sodium intake in packaged foods with the incidence of anemia in adolescent girls at MA Darussa'adah Jakarta. Methods: The design of this research is a cross-sectional study with a purposive sampling technique according to the inclusion and exclusion criteria, totaling 37 respondents. This research was conducted in February 2022. The research instrument is a food recall form 2x24 hours to determine protein intake and sodium intake in packaged foods, SQ-FFQ form to determine the consumption of vegetables and fruits by interviewing respondents. Results: The statistical results of the Pearson correlation test (p 0.825) and a positive pattern of r (0.38), vegetables and fruit (p 0.333) with a positive pattern of r (0.164), sodium intake (p 0.724) with a positive pattern of r (0.60). Conclusion: there is no relationship between protein, vegetable, and fruit intake, sodium intake in packaged foods, and anemia in adolescent girls

Analisis Pengaruh Indeks Pembangunan Manusia dan Tingkat Pengangguran Terbuka Terhadap Kemiskinan di Kota Serang Tahun 2010-2023

Penelitian ini bertujuan untuk menganalisis pengaruh Indeks Pembangunan Manusia (IPM) dan Tingkat Pengangguran Terbuka (TPT) terhadap kemiskinan di Kota Serang selama periode 2010-2023. Data sekunder yang digunakan dalam penelitian ini dikumpulkan dari berbagai sumber resmi, yang kemudian dianalisis menggunakan metode data time series. Metode analisis regresi berganda diterapkan untuk mengidentifikasi dan mengukur hubungan antara variabel IPM dan TPT dengan tingkat kemiskinan. Hasil penelitian menunjukkan bahwa IPM dan TPT memiliki pengaruh signifikan terhadap kemiskinan di Kota Serang. Temuan ini memberikan wawasan penting bagi pembuat kebijakan dalam upaya mengurangi kemiskinan melalui peningkatan kualitas pembangunan manusia dan penurunan tingkat pengangguran. Penelitian ini menyarankan perlunya strategi yang lebih terpadu dan berfokus pada peningkatan IPM serta penurunan TPT untuk mencapai pengurangan kemiskinan yang lebih efektif di masa depan

Integrating The Network Pharmacology and Molecular Docking to Uncover The Potential Mechanism Of Rutin In Fighting Diabetes Mellitus

Introduction: Rutin is a flavonol glycoside that is known to have blood sugar reducing activity. However, its molecular mechanism in reducing blood sugar level remains unclear. This study was employed to elucidate the pharmacological mechanism of rutin as antidiabetic agent. Methods: Potential target of rutin was screened in relevant databases to construct a compound-target network. Network pharmacology was utilized to identify targets associated with disease, gene ontology and KEGG pathways and confirmed its potential binding affinity using Autodock 4.2 assisted by ADT interface. Result: The result highlighted mTor, PIK3R1, and NFKB1R as a potential target of Rutin through network pharmacology. This target involved in the insulin signaling pathways, insulin resistance, type 2 diabetes mellitus, B receptor signaling pathways, AGE-RAGE signaling pathway in diabetic complications and pancreatic cancer. All docking protocols were valid with RMSD value for TNF-a, NF-KB, PI3K were 0.72 Å, 0.67 Å, ​​and 0.54 Å, respectively. The molecular docking has confirmed the potential mechanism of rutin as antidiabetic agent by stably bound with these proteins with estimated free binding energy values of -8.54 kcal/mol (NF-KB), -8.01 kcal/mol (PI3K), and -6.22 kcal/mol (TNF-a). Conclusion: The study has given insight into the molecular mechanism of rutin in the management of DM by stably bound with NF-KB, TNF-a, and PI3K. However, further laboratory experimental research is needed, particularly in vitro and in vivo assa

PRODUCTION OF INDIAN CITRUS RINGSPOT VIRUS FREE PLANTS OF KINNOW EMPLOYING CHEMOTHERAPY COUPLED WITH SHOOT TIP GRAFTING

Indian citrus ringspot virus (ICRSV) is known to cause serious problem in Kinnow (Citrus nobilis Lour × C. deliciosa Tenora). This paper reports the elimination of ICRSV from Kinnow by chemotherapy coupled with shoot tip grafting under in vitro conditions. Nodal segments from infected mother plant (indexed by indirect ELISA and RT-PCR) were cultured on MS medium containing 2-iP (1mg/l) and malt extract (800 mg/l) along with different concentrations of five antiviral chemicals acycloguanosine, azidothymidine, 2,4-dioxohexahydro-1, 2,5-triazine (DHT), ribavirin and 2- thiouracil. Shoot tips of size 0.7 mm were excised from the sprouts of these nodal segments and grafted on to rough lemon (Citrus jambhiri) under aseptic conditions. The plantlets obtained from chemotherapy coupled with in vitro micrografting were indexed by indirect ELISA and RT-PCR after acclimatization. Maximum effect (37% virus elimination) was seen for ribavirin at 25 mg/l followed by 2-thiouracil at 25 mg/l (21.4%) and acyclguanosine at 25 mg/l (20.8%). Azidothymidine and DHT at the tested doses could not eliminate ICRSV. In the present study only those plants/plantlets were considered virus free, which showed negative reaction both with indirect ELISA and RT-PCR

Highlights From the Annual Meeting of the American Epilepsy Society 2022

With more than 6000 attendees between in-person and virtual offerings, the American Epilepsy Society Meeting 2022 in Nashville, felt as busy as in prepandemic times. An ever-growing number of physicians, scientists, and allied health professionals gathered to learn a variety of topics about epilepsy. The program was carefully tailored to meet the needs of professionals with different interests and career stages. This article summarizes the different symposia presented at the meeting. Basic science lectures addressed the primary elements of seizure generation and pathophysiology of epilepsy in different disease states. Scientists congregated to learn about anti-seizure medications, mechanisms of action, and new tools to treat epilepsy including surgery and neurostimulation. Some symposia were also dedicated to discuss epilepsy comorbidities and practical issues regarding epilepsy care. An increasing number of patient advocates discussing their stories were intertwined within scientific activities. Many smaller group sessions targeted more specific topics to encourage member participation, including Special Interest Groups, Investigator, and Skills Workshops. Special lectures included the renown Hoyer and Lombroso, an ILAE/IBE joint session, a spotlight on the impact of Dobbs v. Jackson on reproductive health in epilepsy, and a joint session with the NAEC on coding and reimbursement policies. The hot topics symposium was focused on traumatic brain injury and post-traumatic epilepsy. A balanced collaboration with the industry allowed presentations of the latest pharmaceutical and engineering advances in satellite symposia

Change in Electrical Conductivity of Polymers: Study showing Effect of Dopant Concentration and Temperature

Abstract-Here, in this article, an effect on electrical conductivity of Polyaniline (PANI) and Poly (metatoluidine) (PMT) has been studied by formation of nanocomposites with some doping agents like magnesium perchlorate, TiN, copper (Ι) salt and its complex. The polymers are synthesized by usual method of oxidative polymerization using ammonium persulfate as an oxidizing agent. Increase in conductivity is noticed to a large extent and it is also verified by noting change in band gap with increase in concentration of dopant and temperature as well. Such approach can be used to develop composite structures using some suitable dopant aiming at various electrical applications. Index Terms: nanocomposites, conductivity, band gap, doping, polymerization. 1