Oral Cysticercosis

Human Oral cysticercosis is an usual presentation following parasitic infestation by Taenia Solit,im, in this report, we present a case of oral cysticercosis in a nine year old boy who reported to Ragas Dental College and Hospital, Chennai for treatment of a nodule in his left cheek

Oral lichen planus: An update on pathogenesis and treatment

Oral lichen planus (OLP) is a chronic inflammatory disease that affects the mucus membrane of the oral cavity. It is a T-cell mediated autoimmune disease in which the cytotoxic CD8+ T cells trigger apoptosis of the basal cells of the oral epithelium. Several antigen-specific and nonspecific inflammatory mechanisms have been put forward to explain the accumulation and homing of CD8+ T cells subepithelially and the subsequent keratinocyte apoptosis. A wide spectrum of treatment modalities is available, from topical corticosteroids to laser ablation of the lesion. In this review, we discuss the various concepts in the pathogenesis and current treatment modalities of OLP

Co-existing Dental Anomalies - Talon Cusp and Supernumerary Tooth - A Case Report

Supernumerary tooth is a common dental anomaly present in both maxilla and mandible. It may manifest as an isolated dental anomaly or as a feature of a syndrome. Talon cusp is another dental anomaly and presents as an accessory cusp in both deciduous and permanent dentition. Talon cusp is usually asymptomatic; however, it may present with numerous clinical problems. Talon cusp is clinically manifested in three forms; Talon, Semi-taIon and Trace Talon. Talon cusp, present in a supernumerary tooth is an uncommon dental anomaly. In this article, we present a case report of bifid talon cusp present in a supernumerary tooth along with an overview of classification of talon cusp, different clinical variants, etiopathogenesis, associated syndromes, clinical problems and treatment modalities

Perioral Molluscum Contagiosum in a HIV Seropositive Patient - A Case Report

Molluscum Contagiosum (MC) is a skin and mucous membrane disease of viral origin seen in both children and adults. Molluscum Contagiosum Virus (MCV) is transmitted by person-to-person contact, sexual contact or by fomites. MC is seen in immunocompromised and HIV infected patients. In this article, we report a case of perioral molluscum contagiosum in a HIV seropositive patient along with the pathogenesis of the disease and various treatment modalities

Immunohistochemical study of polycystin-1 in dentigerous cysts

Background: The alterations involved in step-wise transformation of a dental follicle to dentigerous cyst (DC) is not clearly known. Primary cilium and its protein have been hypothesized to be associated with DC. Mutation of a ciliary protein, polycystin-1 (PC1) is associated with autosomal dominant polycystic kidney disease. This study was performed to assess the immunohistochemical expression of PC1 between DC and postfunctional follicular tissue (PFFT). Materials and Methods: Thirty-one consecutive PFFT and 15 DC formed the study group. The PFFT and DC tissues were stained with antibody against PC1. Statistical Package for Social Service was used to analyze data. Descriptive statistics and Student′s Chi-square test were appropriately used. P ≤0.05 was taken as significant. Results: Fifteen DC (100%) and 7 (22.58%) PFFT were positive for PC1. The difference was statistically significant (P = 0.000). PC1 expression was observed in the cytoplasm with varying intensity. Discussion and Conclusion: All PC1 positive epithelial cells′ cytoplasm stained diffusely. Abnormal cytoplasmic expression of PC1 in all positive epithelial lining indicates that the PC1 probably is associated with cystic transformation