13 research outputs found

    THE ROLE OF KNOWLEDGE MANAGEMENT IN THE ORGANIZATIONS

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    KEY KNOWLEDGE MANAGEMENT TECHNOLOGIES IN THE INTELLIGENCE ENTERPRISE

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    Abstract In this rapidly changing world, the future intelligence competitions will be for rapid knowledge discovery and delivery. How to manage this knowledge has become an important issue in the past few decades, and the knowledge management (KM) community has developed a wide range of technologies and applications for both academic research and practical applications. As a part of KM research, this paper surveys and classifies KM technologies using the different categories. Some discussion is presented, indicating future development for knowledge management technologies and its applications. Also, the key enabling and emerging KM technologies that will enable future generations of intelligence enterprises are introduced in this paper. Keywords: knowledge management, technology, intelligence enterprise, knowledge JEL classification: D80, M10, M15, O30 Introduction In this rapidly changing world, the future intelligence competitions will be for rapid knowledge discovery and delivery. The power of knowledge is a very important resource for preserving valuable heritage, creating core competences, learning new things, solving problems, and initiating new situations for both individual and organizations now and in the future (Shu-Hsien Liao, 2003). How to manage this knowledge has become an important issue in the past few decades, and the knowledge management (KM) community has developed a wide range of technologies and applications for both academic research and practical applications. In addition, KM has attracted much effort to explore its nature, concepts, frameworks, architectures, methodologies, tools, functions, real world implementations in terms of demonstrating KM technologies and their applications. In such context, information technology (IT) represent the predominant influence on the progress in creating knowledge and foreknowledge within intelligence organizations. Advances in information technologies and the growth of a knowledge-based economy are transforming the basis of technological innovation and corporate competition. The critical technologies for the intelligence organization will be those that support deep and rapid analysis-synthesis. KM technologies will continue to expand human thinking, collaboration, and problem solving in the intelligence enterpris

    Creating competitive poles – the sustainable model for obtaining the competitive advantage

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    In a global economy that has as its own competitive advantage the transfer of information and goods around the world in real time, the annexes that surround the ecosystem are the centers for innovation founded on hedge & mutual funds, investment scenarios and the development of biotechnology (for developed countries) or for the development of aircrafts or equipment used for the manufacturing of tangible goods (in emergent countries). For these to create synergy there is the idea of clusters, because they offer to the companies the possibility to change and to add dynamism to the microeconomic open system. Although globalization offers the power of global trading, clusters are found in developed countries with economies that can support multidisciplinary interactions, and their creation must be followed by the emergent countries that want to progress in this area. This paper represents a review and a research in progress on creating competitive poles (or clusters) as a sustainable model for obtaining the competitive advantage

    Potential Effects of Romanian Propolis Extracts against Pathogen Strains

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    The impact of globalization on beekeeping brings new economic, scientific, ecological and social dimensions to this field The present study aimed to evaluate the chemical compositions of eight propolis extracts from Romania, and their antioxidant action and antimicrobial activity against seven species of bacteria, including pathogenic ones: Staphylococcus aureus, Bacillus cereus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, Listeria monocytogenes and Salmonella enterica serovar Typhimurium. The phenolic compounds, flavonoids and antioxidant activity of propolis extracts were quantified; the presence of flavones and aromatic acids was determined. Quercetin and rutin were identified by HPLC analysis and characterized using molecular descriptors. All propolis samples exhibited antibacterial effects, especially against P. aeruginosa and L. monocytogenes. A two-way analysis of variance was used to evaluate correlations among the diameters of the inhibition zones, the bacteria used and propolis extracts used. Statistical analysis demonstrated that the diameter of the inhibition zone was influenced by the strain type, but no association between the propolis origin and the microbial activity was found

    Polyphenolic Extract from Sambucus ebulus L. Leaves Free and Loaded into Lipid Vesicles

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    The paper deals with the preparation and characterisation of hydroalcoholic polyphenolic extract from Sambucus ebulus (SE) leaves that was further loaded into three-types of lipid vesicles: liposomes, transfersomes, and ethosomes, to improve its bioavailability and achieve an optimum pharmacological effect. For Sambucus ebulus L.-loaded lipid vesicles, the entrapment efficiency, particle size, polydispersity index and stability were determined. All prepared lipid vesicles showed a good entrapment efficiency, in the range of 75–85%, nanometric size, low polydispersity indexes, and good stability over three months at 4 °C. The in vitro polyphenols released from lipid vehicles demonstrated slower kinetics when compared to the free extract dissolution in phosphate buffer solution at pH 7.4. Either free SE extract or SE extract loaded into lipid vesicles demonstrated a cytoprotective effect, even at low concentration, 5 ug/mL, against hydrogen peroxide-induced toxicity on L-929 mouse fibroblasts’ cell lines. However, the cytoprotective effect depended on the time of the cells pre-treatment with SE extract before exposure to a hydrogen peroxide solution of 50 mM concentration, requiring at least 12 h of pre-treatment with polyphenols with radical scavenging capacity

    Assessment of Behavioral Risk Factors in Chronic Obstructive Airway Diseases of the Lung Associated with Metabolic Syndrome

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    Background: Diet and lifestyle play important roles in preventing and improving chronic diseases, and evaluating behavioral risk factors in these pathologies allows for efficient management. Methods: A clinical study by screening biochemical parameters and pulmonary function was carried out to evaluate behavioral risk factors in obstructive pulmonary disease associated with metabolic syndrome. Results: Of the total of 70 patients included in the clinical study, 46 were men and 24 were women (χ2 = 3.9, p = 0.168). Forty-eight patients presented at least three met risk criteria associated with the metabolic syndrome (19 women and 29 men). Regarding the assessment of lung function, only 7 of the patients presented normal spirometry values (χ2 = 75.28, p 2 = 5.185, p = 0.075). In terms of body weight, 45 of the patients are overweight or obese, most of them declaring that they do not consume enough vegetable products, they consume large amounts of foods of animal origin (meat, milk, eggs) but also super processed foods (food products type of junk food), do not hydrate properly, and are predominantly sedentary people (54 of the patients do no physical activity at all; χ2 = 2.12, p = 0.713). Conclusion: From the statistical processing of the data, it is noted that insufficient hydration, low consumption of vegetables, increased consumption of hyper-caloric food products rich in additives, sedentary lifestyle, and smoking are the main disruptive behavioral factors that worsen the health status in lung disease associated with the metabolic syndrome. An important conclusion emerging from the study is that the imbalances that aggravate obstructive lung diseases are generated by unhealthy food and an unbalanced lifestyle

    Biological Activities and Chemical Profile of Gentiana asclepiadea and Inula helenium Ethanolic Extracts

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    This study aimed to investigate the antioxidant, antimicrobial, and cytotoxic potential of ethanolic extracts obtained from Gentiana asclepiadea L. and Inula helenium L. roots, in relation to their chemical composition. The total polyphenols, flavonoids, and phenolic acids were determined by spectrophotometric methods, while LC-MS analysis was used to evaluate the individual constituents. The antioxidant properties were tested using the FRAP and DPPH methods. The standard well diffusion and broth microdilution assays were carried out to establish in vitro antimicrobial efficacy and minimum inhibitory and bactericidal concentrations. The cytotoxicity was tested on rat intestinal epithelial cells using the MTT assay. The results pointed out important constituents such as secoiridoid glycoside (amarogentin), phenolic acids (caffeic acid, chlorogenic acid, trans-p-coumaric acid, salicylic acid), and flavonoids (apigenin, chrysin, luteolin, luteolin-7-O-glucoside, quercetin, rutoside, and naringenin) and promising antioxidant properties. The in vitro antimicrobial effect was noticed towards several pathogens (Bacillus cereus > Staphylococcus aureus > Enterococcus faecalis > Salmonella typhimurium and Salmonella enteritidis > Escherichia coli), with a pronounced bactericidal activity. Rat intestinal epithelial cell viability was not affected by the selected concentrations of these two extracts. These data support the ethnomedicinal recommendations of these species and highlight them as valuable sources of bioactive compounds
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