Enhanced surface acoustic wave cell sorting by 3D microfluidic chip design

We demonstrate an acoustic wave driven microfluidic cell sorter that combines advantages of multilayer device fabrication with planar surface acoustic wave excitation. We harness the strong vertical component of the refracted acoustic wave to enhance cell actuation by using an asymmetric flow field to increase cell deflection. Precise control of the 3-dimensional flow is realized by topographical structures implemented on the top of the microchannel. We experimentally quantify the effect of the structure dimensions and acoustic parameter. The design attains cell sorting rates and purities approaching those of state of the art fluorescence-activated cell sorters with all the advantages of microfluidic cell sorting

Projektierung von statistischen Erhebungen mit oertlich und zeitlich differenzierter Aussage ueber die Taetigkeiten der Feuerwehren, Leitstellen und Brandschutzdienststellen

Available from TIB Hannover: RA 2039(125) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekSIGLEDEGerman