9 research outputs found
Fishery potential of bullseyes along the west coast of India
Fishery of bullseyes (Family:Priacanthidae), an emerging non-conventional demersal finfish resource, and the stock assessment of the dominant species Priacanthus Camrur(Forsskal) along the west coast of India are presented. The resource constituted on an average 16,8701 during 2000-2004, and the production showed wide interannual fluctuations. Caught mainly by trawl, the group is represented mainly by Pkamrur followed by Prruentatus and Ptayenus. The growth parameters of Pharnrur along the west coast are L_= 410 mm and K = 0.59lyr. This fish was found to attain 182.7 mm, 284 mm, 340.2 mm and 371.3 mm during the
I-IV th years of its life span. The total mortality coefficient (2) off northwest and southwest coasts during the period ranged between 4.46 to 6.14 and 3.99 to 5.45 respectively. The natural mortality (M) was 1.14 for
the west coast while the fishing mortality (F) ranged between 5 and 3.32 off northwest coast and between
4.31 and 1.13 off southwest coast. The annual average yield from northwest region was 6,293 t while the
estimated annual stock, average standing stock and MSY were 8,173 t, 2,069 t, and 6.356 t. respectively. Off
southwest coast, it was 10,578 t, 14,692 t, 3,401 t and 10,620 t respectively. The exploitation ratio (E)
indicated that the resource is optimally exploited
Incision site metastasis: Adding insult to injury
Incision site metastasis is a rare yet well-recognized complication of oncologic operations. We describe the case of a 60-year-old man with a large mass at the site of abdominal incision for a nephrectomy. The operation was performed for infection in an obstructed kidney, which in retrospect harbored malignancy. Percutaneous core biopsy of the mass revealed metastatic conventional renal cell carcinoma (RCC). Surgical resection was obviated by the presence of nodal disease on imaging. Palliative targeted therapy with tyrosine kinase inhibitor was initiated. RCC can not only mimic an inflammatory renal mass radiologically but also coexist with infective renal conditions. Diligent histopathological examination as a routine following nephrectomy for complicated diagnoses is imperative
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Not AvailableFishery of bullseyes (Family:Priacanthidae), an emerging non-conventional demersal finfish resource, and the stock assessment of the dominant species Priacanthus Camrur(Forsskal) along the west coast of India are presented. The resource constituted on an average 16,8701 during 2000-2004, and the production showed wide interannual fluctuations. Caught mainly by trawl, the group is represented mainly by Pkamrur followed by Prruentatus and Ptayenus. The growth parameters of Pharnrur along the west coast are L_= 410 mm and K = 0.59lyr. This fish was found to attain 182.7 mm, 284 mm, 340.2 mm and 371.3 mm during the
I-IV th years of its life span. The total mortality coefficient (2) off northwest and southwest coasts during the period ranged between 4.46 to 6.14 and 3.99 to 5.45 respectively. The natural mortality (M) was 1.14 for
the west coast while the fishing mortality (F) ranged between 5 and 3.32 off northwest coast and between
4.31 and 1.13 off southwest coast. The annual average yield from northwest region was 6,293 t while the
estimated annual stock, average standing stock and MSY were 8,173 t, 2,069 t, and 6.356 t. respectively. Off
southwest coast, it was 10,578 t, 14,692 t, 3,401 t and 10,620 t respectively. The exploitation ratio (E)
indicated that the resource is optimally exploited.Not Availabl
Not Available
Not AvailableFishery of bullseyes (Family:Priacanthidae), an emerging non-conventional demersal finfish resource, and the stock assessment of the dominant species Priacanthus Camrur(Forsskal) along the west coast of India are presented. The resource constituted on an average 16,8701 during 2000-2004, and the production showed wide interannual fluctuations. Caught mainly by trawl, the group is represented mainly by Pkamrur followed by Prruentatus and Ptayenus. The growth parameters of Pharnrur along the west coast are L_= 410 mm and K = 0.59lyr. This fish was found to attain 182.7 mm, 284 mm, 340.2 mm and 371.3 mm during the
I-IV th years of its life span. The total mortality coefficient (2) off northwest and southwest coasts during the period ranged between 4.46 to 6.14 and 3.99 to 5.45 respectively. The natural mortality (M) was 1.14 for
the west coast while the fishing mortality (F) ranged between 5 and 3.32 off northwest coast and between
4.31 and 1.13 off southwest coast. The annual average yield from northwest region was 6,293 t while the
estimated annual stock, average standing stock and MSY were 8,173 t, 2,069 t, and 6.356 t. respectively. Off
southwest coast, it was 10,578 t, 14,692 t, 3,401 t and 10,620 t respectively. The exploitation ratio (E)
indicated that the resource is optimally exploited.Not Availabl
Histopathological analysis of the non - tumour parenchyma following radical nephrectomy: can it predict renal functional outcome?
ABSTRACT Introduction Radical nephrectomy (RN), a recommended treatment option for patients with Renal cell carcinoma (RCC) leads to an inevitable decline in global renal function. Pathological changes in the non-tumour parenchyma of the kidney may help predict the function of the remaining kidney. Materials and Methods Aim of this prospective, observational study was to find histopathological factors in the non-tumor renal parenchyma that could predict the decline in global renal function postoperatively and its association with co-morbidities like diabetes (DM). Data of consecutive patients undergoing RN from December-2013 to January-2015 was collected. Non-tumor parenchyma of the specimen was reported by a dedicated histopathologist. eGFR was calculated using Cockcroft-Gault formula before the surgery and at last follow up of at least 12 months. Results 73 RN specimens were analyzed. Mean follow up was 12.3 months. The mean decrease in eGFR was 22% (p=.0001). Percent decrease in eGFR did not show association with any of the histopathological parameters studied. DM was significantly associated with decrease in percent eGFR (p<0.05) and increase in arteriolar hyalinosis (p=0.004), Glomerulosclerosis (p=0.03) and Interstitial fibrosis/ Tubular atrophy (p=.0001). Maximum size of the tumor showed a negative correlation with percentage change in eGFR (p=.028). Conclusion Histological parameters in the non-tumour portion of the RN specimen may not be able to predict renal function outcome over a short follow up. However, presence of DM was associated with adverse pathological changes and significant decrease in renal function postoperatively
Histopathological analysis of the non - tumour parenchyma following radical nephrectomy: can it predict renal functional outcome?
<div><p>ABSTRACT Introduction Radical nephrectomy (RN), a recommended treatment option for patients with Renal cell carcinoma (RCC) leads to an inevitable decline in global renal function. Pathological changes in the non-tumour parenchyma of the kidney may help predict the function of the remaining kidney. Materials and Methods Aim of this prospective, observational study was to find histopathological factors in the non-tumor renal parenchyma that could predict the decline in global renal function postoperatively and its association with co-morbidities like diabetes (DM). Data of consecutive patients undergoing RN from December-2013 to January-2015 was collected. Non-tumor parenchyma of the specimen was reported by a dedicated histopathologist. eGFR was calculated using Cockcroft-Gault formula before the surgery and at last follow up of at least 12 months. Results 73 RN specimens were analyzed. Mean follow up was 12.3 months. The mean decrease in eGFR was 22% (p=.0001). Percent decrease in eGFR did not show association with any of the histopathological parameters studied. DM was significantly associated with decrease in percent eGFR (p<0.05) and increase in arteriolar hyalinosis (p=0.004), Glomerulosclerosis (p=0.03) and Interstitial fibrosis/ Tubular atrophy (p=.0001). Maximum size of the tumor showed a negative correlation with percentage change in eGFR (p=.028). Conclusion Histological parameters in the non-tumour portion of the RN specimen may not be able to predict renal function outcome over a short follow up. However, presence of DM was associated with adverse pathological changes and significant decrease in renal function postoperatively.</p></div
Clinicopathological Features of Primary Renal Mesenchymal Neoplasms in Adults: A Cross-sectional Study
Introduction: Renal mesenchymal tumours are a subset of primary renal tumours arising from the mesenchymal tissue in the kidney. They are a heterogeneous group of mostly benign tumours that exhibit varied behaviours and molecular characteristics.
Aim: To analyse the wide spectrum of histological subtypes, their unique clinical presentation, and pathological features of primary renal mesenchymal neoplasms.
Materials and Methods: This was a retrospective cross- sectional observational clinicopathological study conducted in Department of General Pathology, Christian Medical College, tertiary care hospital, Vellore, Tamil Nadu, India, looking at data of adult Primary Renal Mesenchymal Tumours (PRMT) for a 15-year period between January 2006 and March 2021. Clinical details such as age, presenting symptoms, and tumour size were obtained from the hospital information system. Histopathology and immunohistochemical slides were reviewed for all the cases. Additional Immunohistochemistry (IHC) and molecular studies were performed for the undifferentiated sarcomas. The tumours were categorised into three groups as recommended by the World Health Organisation (WHO) 2020 classification of soft-tissue tumours based on biological behaviour: benign, intermediate, and malignant. Continuous variables are expressed as mean and Standard Deviation (SD). Comparison of categorical variables between groups was performed using the Chi-squared test. Continuous variables between groups were compared using the Student’s t-test for significance. A p-value of less than 0.05 was considered statistically significant.
Results: Of the 2164 nephrectomies performed for neoplastic conditions, 97 (4.5%) were diagnosed as renal mesenchymal tumours. There were 59 (60.8%) benign, 10 (10.3%) with intermediate biologic behaviour and 28 (28.9%) malignant tumours. The mean ages at presentation were 40.5 years for benign, 43.4 years for intermediate, and 41 years for malignant tumours, respectively. Haematuria was seen in 11 of 38 (29%) intermediate grade and malignant tumours and in only 6 of 59 (10%) benign tumours, a difference that was statistically significant (p-value=0.017). Malignant tumours 24 of 28 (86%) were more likely to be larger (>7 cm) when compared to benign tumours 28 of 59 (47%) at the time of presentation (p-value=0.027). Classical angiomyolipomas constituted 53/59 (90%) of the benign tumours. Of the 10 intermediate grade tumours, epithelioid angiomyolipomas and solitary fibrous tumours were the most common, accounting for 50% and 30% of the intermediate group, respectively. Undifferentiated small round cell sarcoma was the most common malignant neoplasm, making up 12/28 (43%) of the malignant tumours.
Conclusion: The present study found that renal mesenchymal tumours constitute a small but unique group of renal tumours. They are predominantly benign, but up to a quarter are malignant. Malignant tumours tend to be larger and more often present with haematuria. The present study highlights the importance of IHC in the diagnosis of intermediate and malignant mesenchymal tumours and the requirement of exhaustive molecular studies individually tailored to the immuno-profile of malignant tumours