7 research outputs found

    The Effect of Parents’ Stress on Child Academic Functioning

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    Stress helps to elicit goal-oriented action and activate fight or flight responses. However, too much stress can have harmful and impairing effects for the individual experiencing stress (e.g., parents), and those around them (e.g., their children). The research literature suggests an overall positive relation between parents’ stress and their child’s academic achievement, and that this relation is mediated by parent and children’s emotional functioning, and aspects of the overall family environment. However, these relations were examined independently across multiple studies and samples. We examined the relationship between the parents’ stress and their children’s academic performance, along with the mediational roles of parent emotional functioning, child emotional functioning, and the family environment. The sample included 316 caregiver- child dyads who completed clinical assessments of anxiety and depression. Children also completed the Family Environment Scale, which includes the following subscales: Cohesion, Expressiveness, Conflict, Independence, Achievement Orientation, Intellectual-Cultural Orientation, Active-Recreational Orientation, Moral-Religious Emphasis, Organization, and Control. Results indicated that parents’ stress predicted poorer academic achievement in their children, and that this relation was mediated by parent and children’s emotional functioning. However, this relation was not mediated by aspects of the family environment. These findings were inconsistent with the limited existing research in this area and, thus, warrant further study

    The Effect of Parents’ Stress on Child Academic Functioning

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    Stress helps to elicit goal-oriented action and activate fight or flight responses. However, too much stress can have harmful and impairing effects for the individual experiencing stress (e.g., parents), and those around them (e.g., their children). The research literature suggests an overall positive relation between parents’ stress and their child’s academic achievement, and that this relation is mediated by parent and children’s emotional functioning, and aspects of the overall family environment. However, these relations were examined independently across multiple studies and samples. We examined the relationship between the parents’ stress and their children’s academic performance, along with the mediational roles of parent emotional functioning, child emotional functioning, and the family environment. The sample included 316 caregiver- child dyads who completed clinical assessments of anxiety and depression. Children also completed the Family Environment Scale, which includes the following subscales: Cohesion, Expressiveness, Conflict, Independence, Achievement Orientation, Intellectual-Cultural Orientation, Active-Recreational Orientation, Moral-Religious Emphasis, Organization, and Control. Results indicated that parents’ stress predicted poorer academic achievement in their children, and that this relation was mediated by parent and children’s emotional functioning. However, this relation was not mediated by aspects of the family environment. These findings were inconsistent with the limited existing research in this area and, thus, warrant further study

    Characterizing Consumer Smartphone Apps for Virtual Reality–Based Exposure Therapy: Content Analysis

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    BackgroundIn vivo exposure therapy is the most effective treatment for phobias but is often impractical. Virtual reality exposure therapy (VRET) can help overcome critical barriers to in vivo exposure therapy. However, accessible mobile software related to VRET is not well understood. ObjectiveThe purpose of our study is to describe the landscape of accessible smartphone apps with potential utility for clinical VRET. MethodsWe conducted a content analysis of publicly available smartphone apps related to virtual reality on the Google Play Store and the Apple App Store as of March 2020. ResultsThe initial search yielded 525 apps, with 84 apps (52 on the Google Play Store and 32 on the Apple App Store) included for analysis. The most common phobic stimulus depicted was bodies of water or weather events (25/84, 29.8%), followed by heights (24/84, 28.6%), and animals (23/84, 27.4%). More than half of the apps were visually abstract (39/84, 53.5%). Most apps were free to use (48/84, 57.1%), while the rest were free to try (22/84, 26.2%) or required payment for use (14/84, 16.7%), with the highest cost for use being US $6. The average overall app rating was 2.9 stars out of 5, but the number of ratings ranged from 0 to 49,233. None of the 84 apps advertised compliance with the Health Insurance Portability and Accountability Act, offered the ability to monitor data, provided clinician control over variables in the app experiences, or explicitly stated use by or development with clinicians. ConclusionsNone of the smartphone apps reviewed were explicitly developed for phobia therapy. However, 16 of the 84 included apps were considered ideal candidates to investigate further as part of treatment due to their accessibility, depiction of phobia-relevant stimuli, low or no cost, and high user scores. Most of these apps were visually abstract and free to use, making them accessible and potentially flexible as part of clinical exposure hierarchies. However, none of the apps were designed for clinical use, nor did they provide tools for clinician workflows. Formal evaluation of these accessible smartphone apps is needed to understand the clinical potential of accessible VRET solutions

    Leukodystrophy Imaging: Insights for Diagnostic Dilemmas

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    Leukodystrophies, a group of rare demyelinating disorders, mainly affect the CNS. Clinical presentation of different types of leukodystrophies can be nonspecific, and thus, imaging techniques like MRI can be used for a more definitive diagnosis. These diseases are characterized as cerebral lesions with characteristic demyelinating patterns which can be used as differentiating tools. In this review, we talk about these MRI study findings for each leukodystrophy, associated genetics, blood work that can help in differentiation, emerging diagnostics, and a follow-up imaging strategy. The leukodystrophies discussed in this paper include X-linked adrenoleukodystrophy, metachromatic leukodystrophy, Krabbe’s disease, Pelizaeus–Merzbacher disease, Alexander’s disease, Canavan disease, and Aicardi–Goutières Syndrome

    Mapping the Glymphatic Pathway Using Imaging Advances

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    The glymphatic system is a newly discovered waste-clearing system that is analogous to the lymphatic system in our central nervous system. Furthermore, disruption in the glymphatic system has also been associated with many neurodegenerative disorders (e.g., Alzheimer’s disease), traumatic brain injury, and subarachnoid hemorrhage. Thus, understanding the function and structure of this system can play a key role in researching the progression and prognoses of these diseases. In this review article, we discuss the current ways to map the glymphatic system and address the advances being made in preclinical mapping. As mentioned, the concept of the glymphatic system is relatively new, and thus, more research needs to be conducted in order to therapeutically intervene via this system

    Comparison of diagnoses of early-onset sepsis associated with use of Sepsis Risk Calculator versus NICE CG149: a prospective, population-wide cohort study in London, UK, 2020–2021

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    Objective We sought to compare the incidence of early-onset sepsis (EOS) in infants ≥34 weeks’ gestation identified >24 hours after birth, in hospitals using the Kaiser Permanente Sepsis Risk Calculator (SRC) with hospitals using the National Institute for Health and Care Excellence (NICE) guidance.Design and setting Prospective observational population-wide cohort study involving all 26 hospitals with neonatal units colocated with maternity services across London (10 using SRC, 16 using NICE).Participants All live births ≥34 weeks’ gestation between September 2020 and August 2021.Outcome measures EOS was defined as isolation of a bacterial pathogen in the blood or cerebrospinal fluid (CSF) culture from birth to 7 days of age. We evaluated the incidence of EOS identified by culture obtained >24 hours to 7 days after birth. We also evaluated the rate empiric antibiotics were commenced >24 hours to 7 days after birth, for a duration of ≥5 days, with negative blood or CSF cultures.Results Of 99 683 live births, 42 952 (43%) were born in SRC hospitals and 56 731 (57%) in NICE hospitals. The overall incidence of EOS (<72 hours) was 0.64/1000 live births. The incidence of EOS identified >24 hours was 2.3/100 000 (n=1) for SRC vs 7.1/100 000 (n=4) for NICE (OR 0.5, 95% CI (0.1 to 2.7)). This corresponded to (1/20) 5% (SRC) vs (4/45) 8.9% (NICE) of EOS cases (χ=0.3, p=0.59). Empiric antibiotics were commenced >24 hours to 7 days after birth in 4.4/1000 (n=187) for SRC vs 2.9/1000 (n=158) for NICE (OR 1.5, 95% CI (1.2 to 1.9)). 3111 (7%) infants received antibiotics in the first 24 hours in SRC hospitals vs 8428 (15%) in NICE hospitals.Conclusion There was no significant difference in the incidence of EOS identified >24 hours after birth between SRC and NICE hospitals. SRC use was associated with 50% fewer infants receiving antibiotics in the first 24 hours of life
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