Metal-organic framework functionalized poly-cyclodextrin membranes confining polyaniline for charge storage

Crystals of a metal-organic framework, UiO-66, are grown on electrospun crosslinked poly-cyclodextrin (poly-CD) fibrous membranes with an ultrahigh coverage, and polyaniline (PANI) is further confined within the MOF pores. The obtained PANI@UiO-66/poly-CD membranes are used as free-standing electrodes towards use in wearable energy-storage devices. © 2022 The Royal Society of Chemistr

Electrocatalytic Studies of Coral-Shaped Samarium Stannate Nanoparticles for Selective Detection of Azathioprine in Biological Samples

An electrochemical sensor was developed based on the pyrochlore-type binary metal oxide samarium stannate nanoparticles (Sm2Sn2O7 NPs). The Sm2Sn2O7 NPs were prepared using the co-precipitation technique, and they were subjected to physiochemical characterizations such as X-ray diffraction (XRD), Raman spectroscopy, and X-ray photoelectron spectroscopy (XPS). The morphological and elemental information was interpreted by field-emission scanning electron microscopy (FESEM) and high-resolution transmission electron microscopy (HRTEM) analysis. The electrocatalytic sensing of the pharmaceutical drug azathioprine (AZN) was exhibited using cyclic voltammetry (CV) and differential pulse voltammetry (DPV) over the Sm2Sn2O7/GCE (GCE - glassy carbon electrode). The Sm2Sn2O7/GCE had high electrocatalytic behavior for AZN determination with a limit of detection of 4 nM and superior sensitivity of 0.27 μA μM–1 cm–2, and it has a linear range from 0.01 to 948 μM. Furthermore, the Sm2Sn2O7/GCE exhibited excellent selectivity, long-term storage stability, good repeatability, and reproducibility for AZN detection. Additionally, the Sm2Sn2O7/GCE sensor possessed considerable importance for the sensing of AZN in biological fluids for practical applications. We believe that this pyrochlore-based Sm2Sn2O7 NP electrocatalyst can act as a prospective electrode material for the electrochemical determination of AZN in clinical biological applications

Synthesis and Characterization of Pyrochlore-Type Praseodymium Stannate Nanoparticles: An Effective Electrocatalyst for Detection of Nitrofurazone Drug in Biological Samples

Apart from perovskites, the development of different types of pyrochlore oxides is highly focused on various electrochemical applications in recent times. Based on this, we have synthesized pyrochlore-type praseodymium stannate nanoparticles (Pr2Sn2O7 NPs) by using a coprecipitation method and further investigated by different analytical and spectroscopic techniques such as X-ray diffraction, Raman spectroscopy, field emission-scanning electron microscopy, high resolution-transmission electron microscopy, and X-ray photoelectron spectroscopy analysis. Followed by this, we have designed a unique and novel electrochemical sensor for nitrofurazone detection, by modifying the glassy carbon electrode (GCE) with the prepared Pr2Sn2O7 NPs. For that, the electrochemical experiments were performed by using cyclic voltammetry and differential pulse voltammetry techniques. The Pr2Sn2O7 NPs modified GCE exhibits high sensitivity (2.11 μA μM−1 cm−2 ), selectivity, dynamic linear ranges (0.01−24 μM and 32−332 μM), and lower detection limit (4 nM). Furthermore, the Pr2Sn2O7 NPs demonstrated promising real sample analysis with good recovery results in biological samples (human urine and blood serum) which showed better results than the noble metal catalysts. Based on these results, the present work gives clear evidence that the pyrochlore oxides are highly suitable electrode materials for performing outstanding catalytic activity toward electrochemical sensors

SrMnO₃/Functionalized h-BN Composite Modified Disposable Sensor for the Voltammetric Determination of Furaltadone Antibiotic Drug

Improper disposal of pharmaceutical drugs, including antibiotics, can affect the ecological system and generate serious health problems for living organisms. In this work, we have developed an electrochemical sensor based on a strontium manganese oxide/functionalized hexagonal boron nitride (SrMnO3/f-BN) electrocatalyst for the detection of the antibiotic drug furaltadone (FLD). Various analytical techniques were used to characterize the physicochemical properties of the as-prepared SrMnO3/f-BN composite. The as-fabricated SrMnO3/f-BN composite electrode showed excellent sensing activity towards FLD, with a wide linear range (0.01–152.11 µM) and low detection limit (2.0 nM). The sensor exhibited good selectivity towards FLD for detection in the presence of various interfering species (nitro compounds, metal ions, and biological compounds). Interestingly, real-time analysis using the proposed SrMnO3/f-BN composite was able to determine the FLD content in human urine and wastewater samples with good recovery. Hence, the as-developed SrMnO3/f-BN modified sensor could be viable in practical applications to target the antibiotic drug FLD in both human fluids and environmental samples

SrMnO3/Functionalized h-BN Composite Modified Disposable Sensor for the Voltammetric Determination of Furaltadone Antibiotic Drug

Improper disposal of pharmaceutical drugs, including antibiotics, can affect the ecological system and generate serious health problems for living organisms. In this work, we have developed an electrochemical sensor based on a strontium manganese oxide/functionalized hexagonal boron nitride (SrMnO3/f-BN) electrocatalyst for the detection of the antibiotic drug furaltadone (FLD). Various analytical techniques were used to characterize the physicochemical properties of the as-prepared SrMnO3/f-BN composite. The as-fabricated SrMnO3/f-BN composite electrode showed excellent sensing activity towards FLD, with a wide linear range (0.01–152.11 µM) and low detection limit (2.0 nM). The sensor exhibited good selectivity towards FLD for detection in the presence of various interfering species (nitro compounds, metal ions, and biological compounds). Interestingly, real-time analysis using the proposed SrMnO3/f-BN composite was able to determine the FLD content in human urine and wastewater samples with good recovery. Hence, the as-developed SrMnO3/f-BN modified sensor could be viable in practical applications to target the antibiotic drug FLD in both human fluids and environmental samples