Mapping the Social Across Lived Experiences: Relational Geographies and After-School Time

This article is divided into two sections. The first offers a theoretical frame that enables key concepts to be defined and discussed. The second reviews current approaches to methodology that enable researchers to study the movement of youth over time and across space in an effort to examine the learning that is occasioned by different relationships. Here, we offer ways to begin thinking about mapping social relationships across lived experiences. The article ends with a brief conclusion, in which we note the significance of documenting the developing experiences of children and youth, mediated by social relationships, and the necessity of research and methodologies that attend to these relationships

Experimental Overlay of Glazon over Two Bridge Decks

In accordance with a Personal Service Agreement entered into with the Glazon Industries, Inc., on July 2, 1971, the two subject decks were patched and overlayed with Glazon. On July 27, 1971, work started on RP 106-286-HG3, KY 395 bridge over I 64 in Shelby County. Work consisted of routing old concrete and sandblasting the surface (Figures 1 and 2). State personnel and equipment were used for all cleaning operations. The same procedures were followed to clean HM 99-1324A-MB3 in Powell County near Clay City. On July 28, 1971, Glazon personnel and equipment arrived at the work site in Shelby County. Glazon representatives judged the cleaning adequate and proceeded with patching the southbound lane (Figure 3). No accurate information is available as to the exact formulation of the Glazon used or proportions in the mix. Glazon Industries declined disclosure of such information since their material was not patented. Before patching, the holes were thoroughly dried. Shrinkage and cracking were noticed in the patches shortly after drying (Figure 4). Later, on other lanes, patch holes were primed with a Glazon liquid before patching (Figures 5 and 6). After a short drying period, the deck was sprayed with a Glazon mix similar to that for patching but more fluid (Figures 7 and 8). Some problems were encountered due to weak air supply, but were shortly overcome. The sprayed deck looked satisfactory to Glazon personnel who did most of the work in patching and overlaying the deck. The operation was moved to the Clay City bridge and the same procedures were followed in working the northbound lane. Two wingwalls on the Shelby County bridge were sprayed with a Glazon mix made with white cement. On August 3, 1971, both bridges were completed though work was interrupted by rain several times. On August 5, 1971, both bridges were reopened to two-lane traffic. This Division closely observed these operations from the beginning. It was later learned from the Division of Maintenance that the northbound lane of the Shelby County deck, which was badly deteriorating, had been repaired on September 15, 1971

Relative contributions of solid skeleton visco-plasticity and water viscosity to the poro-mechanics behavior of callovo-oxfordian claystone

The Callovo-Oxfordian claystone is a saturated porous medium. Its transfer properties, including its low permeability [16] make it an interesting candidate for underground radioactive waste disposal. The drained tests performed on the claystone, collected by ANDRA1 from samples at 500 meters depth [16, 9], exhibits a damageable visco-elasto-plastic behavior. This viscous behavior includes both the viscosity of the skeleton and the water. In existing models [5, 6, 11, 1], the creep phenomena are attributed either to the water permeability, to the skeleton visco-plasticity or sometimes both [13]. In a first step, a simplified analysis is proposed to understand the contribution of each phenomenon with respect to the consolidation time. This study indicates that the apparent characteristic time is the sum of those related to the skeleton and water permeability. To handle both non-linear and viscous phenomena, the damage law [15], coupled with the basic creep model [14] is used to characterize the solid skeleton of the claystone. The fluid behavior is integrated with the poro-mechanical model [7] implemented in the finite element code CAST3M [4]. The proposed model (visco-elastic damageable skeleton + saturating fluid) is used to simulate an excavation from the ANDRA underground laboratory (located in Bure–France). This application allows the understanding of how both viscous phenomena combine at each step of the calculation. Just after the excavation, water overpressure decreases near the gallery approaching zero due to the damage and then increases the permeability. The viscosity is then controlled by the solid skeleton creep rates. Later, the redistribution of hydraulic pressure is of more importance and permeability again plays a major role

Development of a biosensor for fast point-of-care blood analysis of Troponin

We present the development of novel tetrapolar EIS biosensor for the detect of troponin. Troponin has considerable diagnostic power and provide invaluable prognostic information for risk stratification. of acute coronary syndromes. Clinical Relevance— A feasibility study was undertaken to assess the diagnostic performance of serial cardiac troponin measurements which is excellent as these structural proteins are unique to the heart and thus sensitive and specific of damage to the myocardium. clinical molecular diagnostics and home healthcare. Troponin’s biosensors would provide point-of-care and rapid decision making for the early detection of CS. Clinically relevant window of cTnI testing, concentrations from 10pM to 0.1μM were achieved

A low-power recursive I/Q signal generator and current driver for bioimpedance applications

This brief presents a power-efficient quadrature signal generator and current driver application-specific integrated circuit (ASIC) for bioimpedance measurements in an electrical impedance tomography system for monitoring lung function. The signal generator is realized by a digital recursive signal oscillator with the ability of generating quadrature signals over a wide frequency range. The generated in-phase signal is applied to a current driver. It uses a balanced current-mode feedback architecture that monitors the output current through a feedback loop to minimize common-mode voltage build-up at the injection site. The quadrature signals can be used for I/Q demodulation of the measured bioimpedance. The ASIC was designed in TSMC 65 nm technology occupying an area of 0.21 mm2. The current driver can generate up to 0.7 mA current up to 200 kHz and consumes 2.7 mW power using ±0.8 V supplies

Prevention of early stage Kras-mutant lung adenocarcinoma via targeted KrasG12D inhibition

https://openworks.mdanderson.org/sumexp22/1118/thumbnail.jp

Spontaneous appearance of de novo intracranial arteriovenous malformation in hepatic cirrhosis

BACKGROUND Intracranial arteriovenous malformations (AVMs) are rare lesions that can be congenital or acquired in early childhood, with fatal outcome in approximately 30% of cases. De novo formation during adulthood without established predisposing vascular pathology or previous brain insult is even less frequent. CASE DESCRIPTION We present a case of de novo brain AVM in an alcoholic Child-B cirrhosis setting. Thirty previously reported cases presented de novo AVM in patients of all ages that had another previous brain pathology or insult, such as AVM resection. Seventeen of those cases occurred in adult patients, with only 2 showing no significant predisposing factor. The present pathophysiological review covers and completes Mullan's hemodynamic "two-hit" model, associating probable thrombotic predisposition to AVM with brain insult triggering a later stage based on angiogenic stimuli. CONCLUSIONS This case report and literature review renews previously discussed hemodynamic theories and contributes to a fuller understanding of the pathogenesis and progression of AVM. We postulate a causal link between hepatopathy and de novo AVM, which should be strengthened and interpreted based on recent genetic data and future prospective studies

Monolithic large-signal transimpedance amplifier for use in multi-gigabit, short-range optoelectronic interconnect applications

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Properties Study of ZnS Thin Films Prepared by Spray Pyrolysis Method

Zinc sulfide (ZnS) is important II-VI semiconductors material for the development of various modern technologies and photovoltaic applications. ZnS thin film was prepared by using chemical spray pyrolysis technique. The starting solution is a mixture of 0.1 M zinc chloride as source of Zn and 0.05 M thiourea as source of S. The glass substrate temperature was varied in the range of 300 °C-400 °C to investigate the influence of substrate temperature on the structure, chemical composition, morphological and optical properties of ZnS films. The DRX analyses indicated that ZnS films have polycrystalline cubic structure with (111) preferential orientation and grain size varied from 25 to 60 nm, increasing with substrate temperature. The optical properties of these films have been studied in the wavelength range 300-2500 nm using UV-VIS spectro-photometer. The ZnS films has a band gap of 3.89 eV-3.96 eV